T Cell News and Research

Latest T Cell News and Research

Transplanting mesenchymal stromal cells derived from amniotic membranes can benefit eye diseases

A team of researchers in South Korea has successfully transplanted mesenchymal stromal cells (MSCs) derived from human amniotic membranes of the placenta (AMSCs) into laboratory mice modeled with oxygen-induced retinopathy (a murine model used to mimic eye disease).

20 Aug 2015

Amherst neurobiologists awarded grant to study how neurons regulate locomotion

Neurobiologist Gerald Downes, with chemist James Chambers at the University of Massachusetts Amherst and Amherst College neurobiologist Josef Trapani, have been awarded a three-year $824,025 collaborative research grant from the National Science Foundation to study the zebrafish brain to better understand how neurons regulate locomotion.

20 Aug 2015

Researchers reveal new pathway that governs proper sorting of essential synaptic proteins in neurons

Genetic analysis of human patients has shown that mutations in genes involved in synaptic communication can drive neuropsychiatric and neurological diseases such as autism spectrum disorder and Alzheimer's disease.

20 Aug 2015

Researchers uncover genetic circuit involved in obesity

Like many other conditions, obesity is caused by an interplay between genetic and environmental factors. While efforts to combat the obesity epidemic will need to include changes in diet and exercise, insights into the genes involved may also help with prevention and treatment.

20 Aug 2015

Boston Scientific receives FDA approval for Innova Vascular Self-Expanding Stent System

Boston Scientific Corporation has received Food and Drug Administration approval for the Innova Vascular Self-Expanding Stent System, an advanced treatment option for patients with narrowing or blockages in the superficial femoral artery (SFA) or proximal popliteal artery (PPA).

20 Aug 2015

MCRI announces winners of cancer crowdsourcing initiative

The Myeloma Crowd Research Initiative (MCRI), an unprecedented collaboration of cancer researchers and patient advocates, today announced the two winners of its first-ever crowdsourcing and patient-led initiative to fund research in high-risk multiple myeloma, a rare malignancy of plasma cells.

19 Aug 2015

PHD1 inhibition may have therapeutic potential for colorectal cancer

Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy. Chemotherapy resistance remains a major clinical issue in the treatment of CRC. These findings indicate that PHD1 inhibition may have valuable therapeutic potential. The study was published in the leading medical journal EMBO Molecular Medicine, which features molecular biology-driven research.

19 Aug 2015

EnGeneIC begins Phase 1 Tailored-EDV trial for advanced solid tumor

EnGeneIC Ltd., an emerging biopharmaceutical company focused on developing its proprietary EDV™ nanocell platform for the targeted delivery of cancer therapeutics, today announced that the first patient has been dosed in its Phase 1 Tailored-EDV trial. The trial is being conducted at the Northern Cancer Institute in Sydney, Australia.

19 Aug 2015

Further understanding of genetic influence in ALS to be explored in new partnership

Biogen, the ALS Association and Columbia University Medical Center (CUMC) today announced a new collaboration to better understand the differences and commonalities in the ALS disease process and how genes influence the clinical features of the disease.

19 Aug 2015

Discovery allows study of naturally occurring forms of HCV in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective treatments.

19 Aug 2015

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Dr. Badiavas’ research demonstrates how mesenchymal stem cell (MSC) exosomes, cell-derived vesicles that exist in biological fluids, function to repair non-healing wounds.

19 Aug 2015

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Doctor Scott Mueller and colleagues from the University of Melbourne's Department of Microbiology and Immunology at the Doherty Institute used state-of-the-art microscopy to painstakingly capture images of the interactions of three crucial types of immune cells rallying to destroy herpes simplex virus.

19 Aug 2015

Early exposure to inflammatory cytokines can paralyze CD4 T cells

In a discovery that is likely to rewrite immunology text books, researchers at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can "paralyze" CD4 T cells, immune components that help orchestrate the body's response to pathogens and other invaders.

19 Aug 2015

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

In experiments with 500,000 genetically engineered zebrafish embryos, Johns Hopkins scientists report they have developed a potentially better and more accurate way to screen for useful drugs, and they have used it to identify 24 drug candidates that increase the number of insulin-producing cells in the pancreas.

19 Aug 2015

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.

19 Aug 2015

Scientists identify new pathway that may protect brain from Alzheimer's disease

It is a hallmark of Alzheimer's disease: Toxic protein fragments known as amyloid-β clumped together between neurons in a person's brain.

19 Aug 2015

Researchers at Forsyth Institute enhance pipetting efficiency using VIAFLO Assist

INTEGRA reports on how researchers at the renowned Forsyth Institute (Cambridge, MA) are using a VIAFLO Assist to enhance the efficiency while maintaining the accuracy of pipetting protocols related to the discovery, measurement, and validation of new biomarkers of disease that can be found in saliva.

From INTEGRA Biosciences 18 Aug 2015

Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Omeros Corporation today announced additional positive data in the company's Phase 2 clinical trial of OMS721 for the treatment of thrombotic microangiopathies (TMAs). TMAs are a family of rare, debilitating and life-threatening disorders characterized by excessive thrombi (clots) – aggregations of platelets – in the microcirculation of the body's organs, most commonly the kidney and brain.

18 Aug 2015

Researchers describe central role of mTOR in ageing and age-related diseases

For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it's a cellular pathway that's found in everything from yeast to mammals.

18 Aug 2015

CMU BrainHub scientists use non-invasive brain-imaging tool to detect basal ganglia pathways

Certain diseases, like Parkinson's and Huntingdon's disease, are associated with damage to the pathways between the brain's basal ganglia regions. The basal ganglia sits at the base of the brain and is responsible for, among other things, coordinating movement. It is made up of four interconnected, deep brain structures that imaging techniques have previously been unable to visualize.

18 Aug 2015

T Cell News and Research

Latest T Cell News and Research

Transplanting mesenchymal stromal cells derived from amniotic membranes can benefit eye diseases

Amherst neurobiologists awarded grant to study how neurons regulate locomotion

Researchers reveal new pathway that governs proper sorting of essential synaptic proteins in neurons

Researchers uncover genetic circuit involved in obesity

Boston Scientific receives FDA approval for Innova Vascular Self-Expanding Stent System

MCRI announces winners of cancer crowdsourcing initiative

PHD1 inhibition may have therapeutic potential for colorectal cancer

EnGeneIC begins Phase 1 Tailored-EDV trial for advanced solid tumor

Further understanding of genetic influence in ALS to be explored in new partnership

Discovery allows study of naturally occurring forms of HCV in the lab

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Early exposure to inflammatory cytokines can paralyze CD4 T cells

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Scientists identify new pathway that may protect brain from Alzheimer's disease

Researchers at Forsyth Institute enhance pipetting efficiency using VIAFLO Assist

Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Researchers describe central role of mTOR in ageing and age-related diseases

CMU BrainHub scientists use non-invasive brain-imaging tool to detect basal ganglia pathways

Immunology eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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