T Cell News and Research

Latest T Cell News and Research

Epic Sciences presents single cell sequencing data from mCRPC patients at 2015 ASCO

Epic Sciences announced today that the company will present single cell sequencing data, from metastatic castrate resistant prostate cancer patients, at the 2015 annual meeting of the American Society for Clinical Oncology. This application expands the investigational utility of Epic Sciences' no cell left behind™ platform to characterize circulating tumor cell (CTC) genomic alterations.

1 Jun 2015

Additional preclinical data on DelMar’s VAL-083 to treat temozolomide-resistant GBM presented at AACR

DelMar Pharmaceuticals, Inc., a biopharmaceutical company focused on developing and commercializing proven cancer therapies in new orphan drug indications, presented additional preclinical data at the American Association of Cancer Research (AACR) Advances in Brain Cancer Research Conference on the potential for its lead product candidate VAL-083 (dianhydrogalactitol) to treat patients with temozolomide-resistant glioblastoma multiforme (GBM).

1 Jun 2015

Amgen and Merck expand collaboration for Talimogene laherparepvec-KEYTRUDA combination study

Amgen and Merck, known as MSD outside the U.S. and Canada, today announced an expanded collaboration to evaluate the efficacy and safety of talimogene laherparepvec, Amgen's investigational oncolytic immunotherapy, in combination with KEYTRUDA® (pembrolizumab), Merck's anti-PD-1 therapy, in a Phase 1, open-label trial of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN).

1 Jun 2015

Novartis to highlight strength of its expanded oncology portfolio at ASCO 2015

Novartis will highlight the strength of its expanded oncology portfolio in 21 medicines and 11 investigational compounds across more than 185 data presentations at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting, May 29-June 2, and the Congress of the European Hematology Association (EHA), June 11-14.

1 Jun 2015

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL

Pharmacyclics, Inc. today announced the initiation of PCYC-1136-CA, a multi-center study that will investigate the use of ibrutinib (IMBRUVICA®) in combination with MEDI4736, an investigational anti-PD-L1 immune checkpoint inhibitor being developed by AstraZeneca.

1 Jun 2015

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

The rapidly emerging field of precision medicine is a "disruptive innovation" that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week's issue of the New England Journal of Medicine.

1 Jun 2015

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

It's a new weapon in the arsenal of cancer fighting treatments: utilizing genetically modified viruses to invade cancer cells and destroy them from the inside.

1 Jun 2015

New data indicates that most microbes behave similarly on Earth and International Space Station

Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places.

1 Jun 2015

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Prometheus Laboratories, Inc. announced today the presentation of updated data from the PROCLAIM national patient registry in which first-line Proleukin® (aldesleukin for injection) therapy improved survival in patients with metastatic renal cell carcinoma (mRCC), compared to patients previously treated with targeted therapies.

1 Jun 2015

Space Aging study may help identify novel genes linked to longevity

The plot of many a science fiction TV series or movie revolves around the premise that people traveling long distances in space age more slowly than their counterparts on Earth. Now, tiny worms who spent time aboard the International Space Station could help humans understand more about the effects of aging in space for real.

1 Jun 2015

FLI invites scientific elite to EKF Symposium on Adult Stem Cells in Aging, Diseases and Cancer

It's already for the fourth time, that Prof. Dr. K. Lenhard Rudolph, scientific director of the Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI) calls the scientific elite of international stem cell researchers to join at Else Kröner Fresenius (EKF) Symposium on Adult Stem Cells in Aging, Diseases and Cancer.

1 Jun 2015

Astute Medical's NephroCheck Test obtains measurements of two biomarkers that act as alarm for AKI risk

An intervention known as remote ischemic preconditioning (RIPC) significantly reduced the occurrence of acute kidney injury (AKI) in cardiac surgery patients and confirmed that post-operative elevations of two kidney biomarkers act as an alarm for risk of AKI, according to a study published online today in the Journal of the American Medical Association.

30 May 2015

Palbociclib drug shows promise in women with HR+ metastatic breast cancer

Despite advances in managing and curing some forms of breast cancer, women whose disease becomes metastatic have fewer effective options. A new phase 3 study in some of the most difficult-to-treat patients, women with endocrine-resistant disease, showed that the newly approved drug, palbociclib, more than doubled the time to cancer recurrence for women with hormone-receptor (HR+) positive metastatic breast cancer.

30 May 2015

Over 700 Chinese patients with acute myeloid leukemia undergo Microtransplantation treatment

According to Dr. Huisheng Ai's team, founder of Microtransplantation regimen mainly for Acute Myeloid Leukemia, over 700 patients have undergone this therapy since its emergence in 2002. Based at MST International Clinic for Leukemia in the 307th Hospital of Chinese People's Liberation Army in Beijing, about 40 hematology centers covering all main hospitals in 32 provinces of mainland China have adopted Microtransplantation regimen.

30 May 2015

Ibrutinib and chemotherapy reduce risk of death in patients with CLL or SLL

Because of the significant benefit found in combining the targeted drug ibrutinib with standard chemotherapy for relapsed chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), an interim analysis has closed the international HELIOS phase III clinical trial.

30 May 2015

Positive results from pacritinib Phase 3 trial for treatment of myelofibrosis presented at ASCO 2015

CTI BioPharma Corp. and Baxter International's Bioscience business today announced data from PERSIST-1 – a randomized Phase 3 registration-directed trial examining pacritinib for the treatment of myelofibrosis – in a late-breaking oral session at the 51st Annual Meeting of the American Society of Clinical Oncology, May 29-June 2, 2015 in Chicago, Ill.

30 May 2015

Researchers identify 763 proteins in human aqueous humor that nourish the cornea and the lens

Researchers conducting a comprehensive proteomics analysis of human aqueous humor samples identified 763 proteins - including 386 proteins detected for the first time - in this clear fluid that helps maintain pressure in the eye and nourishes the cornea and the lens.

30 May 2015

PEPRR intervention successfully reduces stress of cancer caregivers

Stem cell transplant is essential in the care of many blood cancers, but leaves patients requiring in-home care for months after.

30 May 2015

KeyGenes platform could be useful for testing quality of stem cell transplants

A snapshot of gene activity is now all that's necessary to determine what organ or tissue type that a cluster of fetal stem cells will ultimately become. An algorithm developed by a team of Dutch scientists makes it possible to match what's happening inside of an immature stem cell to known human fetal cell gene expression, thus identifying what the stem cell has the potential to be.

30 May 2015

RPCI-led research team to share clinical results of entolimod drug at ASCO 2015

A collaborative team of researchers led by Alex A. Adjei, MD, PhD, FACP, of Roswell Park Cancer Institute (RPCI) will share results from the first clinical study of the anticancer effects of the novel agent entolimod at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

30 May 2015

T Cell News and Research

Latest T Cell News and Research

Epic Sciences presents single cell sequencing data from mCRPC patients at 2015 ASCO

Additional preclinical data on DelMar’s VAL-083 to treat temozolomide-resistant GBM presented at AACR

Amgen and Merck expand collaboration for Talimogene laherparepvec-KEYTRUDA combination study

Novartis to highlight strength of its expanded oncology portfolio at ASCO 2015

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

New data indicates that most microbes behave similarly on Earth and International Space Station

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Space Aging study may help identify novel genes linked to longevity

FLI invites scientific elite to EKF Symposium on Adult Stem Cells in Aging, Diseases and Cancer

Astute Medical's NephroCheck Test obtains measurements of two biomarkers that act as alarm for AKI risk

Palbociclib drug shows promise in women with HR+ metastatic breast cancer

Over 700 Chinese patients with acute myeloid leukemia undergo Microtransplantation treatment

Ibrutinib and chemotherapy reduce risk of death in patients with CLL or SLL

Positive results from pacritinib Phase 3 trial for treatment of myelofibrosis presented at ASCO 2015

Researchers identify 763 proteins in human aqueous humor that nourish the cornea and the lens

PEPRR intervention successfully reduces stress of cancer caregivers

KeyGenes platform could be useful for testing quality of stem cell transplants

RPCI-led research team to share clinical results of entolimod drug at ASCO 2015

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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