T Cell News and Research

Latest T Cell News and Research

Findings lead to new drugs that block cancers from spreading to bone

When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system.

30 Aug 2013

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

A Cedars-Sinai team of researchers led by principal investigator Dan Gazit, PhD, DMD, has been awarded a $5.18 million grant from California's stem cell research agency to advance stem cell technologies in segmental bone defects, a complex medical problem caused by large portions of bone tissue loss.

30 Aug 2013

Scientists identify enzyme mutation that occurs in castration-resistant prostate cancer

The mutation occurs in the androgen-synthesizing enzyme 3βHSD1 in castration-resistant prostate cancer (CRPC), according to research published online today in Cell. This mutation enables the tumor to make its own supply of androgens, a hormone that fuels the growth of the prostate cancer.

30 Aug 2013

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

A team of researchers led by Janet Stanford, Ph.D., of Fred Hutchinson Cancer Research Center has discovered that mutations in the gene BTNL2, which encodes a protein involved in regulating T-cell proliferation and cytokine production - both of which impact immune function - increase the risk of developing prostate cancer.

30 Aug 2013

Stem cell researchers receive Early Translational research awards from CIRM

Four prominent researchers from UCLA's Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational research awards totaling approximately $13 million from the California Institute for Regenerative Medicine (CIRM) the state stem cell agency. The UCLA researchers received four of the 12 total awards; no other applicant institution received more than one award.

30 Aug 2013

BP and headache drug effectively speeds up treatment of TB

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in four months instead of the usual six.

30 Aug 2013

Diabetic patients could benefit from breakthrough cell study

Diabetic patients could benefit from a breakthrough that enables scientists to take cells from the pancreas and change their function to produce insulin.

30 Aug 2013

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell.

30 Aug 2013

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

A new weakness has been discovered in cancer cells that may make them more susceptible to chemotherapy and other treatments. In a research report appearing in the September 2013 issue of The FASEB Journal, scientists identify the HDAC5 protein as being essential for the maintenance of structures, called telomeres, within cancer cells that promote cancer cells longevity.

30 Aug 2013

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

According to new research published in The FASEB Journal, a drop in blood zinc levels does not directly harm the blood vessel cells. Rather, zinc regulates the production of a small molecular compound, which then circulates in the blood and causes harmful blood vessel cell effects.

30 Aug 2013

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Researchers have identified a novel disease gene in which mutations cause rare but devastating genetic diseases known as mitochondrial disorders.

30 Aug 2013

Albumin-bound paclitaxel has favorable risk–benefit profile in NSCLC

Albumin-bound paclitaxel plus carboplatin is an effective and well-tolerated first-line treatment in patients with advanced non-small-cell lung cancer, irrespective of histology, study results show.

29 Aug 2013

Malignant Hyperthermia Scientific Conference to be held at University of Toronto

The 2013 Malignant Hyperthermia (MH) Scientific Conference is being held at the Chestnut Conference Centre, University of Toronto, Canada on November 1st and 2nd, 2013 and is sponsored by Malignant Hyperthermia Association of the United States (MHAUS) in conjunction with The University of Toronto.

29 Aug 2013

Scientists develop complex human brain tissue in 3D culture system

Complex human brain tissue has been successfully developed in a three-dimensional culture system established in an Austrian laboratory. The method described in the current issue of NATURE allows pluripotent stem cells to develop into cerebral organoids - or "mini brains" - that consist of several discrete brain regions.

29 Aug 2013

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

Researchers at Lund University have unexpectedly discovered that an old cancer drug can be used to prevent rejection of transplanted tissue. The researchers now have high hopes that their discovery could lead to new treatments for both transplant patients and patients with autoimmune diseases.

29 Aug 2013

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Pharmacyclics, Inc. (Nasdaq: PCYC) today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing its New Drug Application (NDA) for the investigational oral Bruton's tyrosine kinase (BTK) inhibitor ibrutinib, for two B-cell malignancy indications: previously treated mantle cell lymphoma (MCL) and previously treated chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

29 Aug 2013

Scientists develop method to generate functioning brain cells that produce myelin

Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue. Findings from a team of UC Davis investigators have brought this dream a step closer by developing a method to generate functioning brain cells that produce myelin - a fatty, insulating sheath essential to normal neural conduction.

29 Aug 2013

T Cell News and Research

Latest T Cell News and Research

Findings lead to new drugs that block cancers from spreading to bone

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

Scientists identify enzyme mutation that occurs in castration-resistant prostate cancer

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

Stem cell researchers receive Early Translational research awards from CIRM

BP and headache drug effectively speeds up treatment of TB

Diabetic patients could benefit from breakthrough cell study

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Albumin-bound paclitaxel has favorable risk–benefit profile in NSCLC

Malignant Hyperthermia Scientific Conference to be held at University of Toronto

Scientists develop complex human brain tissue in 3D culture system

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Scientists develop method to generate functioning brain cells that produce myelin

Researchers identify novel mechanism that particular superbug uses to fend off antibiotic

Problems with key enzymes potentially lead to autism spectrum disorder

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

Immunology eBook

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Newsletters you may be interested in