T Cell News and Research

Latest T Cell News and Research

Canopy Biosciences introduces high-plex spatial biology assay for quantitative immune cell profiling

Canopy Biosciences, a Bruker Company, today announced the launch of its Spatial Immune Cell Profiling Assay for formalin-fixed paraffin-embedded (FFPE) tissue samples.

From Bruker Nano Surfaces and Metrology 7 Apr 2021

Antifungal and antidepressant drugs can effectively inhibit COVID-19 virus

New research published in the British Journal of Pharmacology indicates that two currently available medications--an antifungal drug and an antidepressant--can effectively inhibit the virus that causes COVID-19 in laboratory cells.

7 Apr 2021

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

7 Apr 2021

Researchers discover two new ways to treat small cell lung tumors

Using samples of small cell lung tumors, a research team led by biologist Dr Silvia von Karstedt has discovered two new ways to induce tumor cell death. One of two subsets of tumor cells can be targeted by activating ferroptosis: iron-dependent cell death caused by oxidative stress

7 Apr 2021

Cell phone GPS data helps predict energy demand more accurately

Researchers at The University of Texas at San Antonio (UTSA) are surveying households in two San Antonio zip codes, 78230 and 78202, about their energy use, mobility and chronic health conditions. Once the survey is complete, the data will be combined with cell phone GPS data to improve the ability to predict energy demand through time at the neighborhood level.

7 Apr 2021

Researchers determine key protein structure that may lead to effective treatments for schizophrenia

Glycine is the smallest amino acid - one of the building blocks of proteins. It acts also as a neurotransmitter in the brain, enabling neurons to communicate with each other and modulating neuronal activity.

7 Apr 2021

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

7 Apr 2021

High-intensity walking exercise benefits people with peripheral artery disease

No pain means no gain when it comes to reaping exercise benefits for people with peripheral artery disease (PAD), reports a new Northwestern Medicine study.

6 Apr 2021

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

A $10.8 million grant from the National Institutes of Health will enable an interdisciplinary team of researchers at the University of Arkansas and University of Arkansas for Medical Sciences to address the role of cell and tissue metabolism in rare and common diseases such as cancer, diabetes, obesity and mitochondrial disorders.

6 Apr 2021

Tissue architecture impacts the evolutionary course of cancer

Tumors are genetically diverse with different mutations arising at different times throughout growth and development.

6 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Study discovers how microcephaly and blindness may develop in Zika-infected fetuses

A study led by Edward Wojcik, PhD, Associate Professor of Biochemistry & Molecular Biology at LSU Health New Orleans School of Medicine, identified how microcephaly (abnormally small heads) and blindness may develop in Zika-infected fetuses, as well as a new way to potentially prevent these neurodevelopmental defects.

6 Apr 2021

Natural selection and adaptation of SARS-CoV-2 in mammals

Researchers of the Hubei University of Medicine, China, have analyzed several mutations in different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from mammal species that suggest natural selection and host adaptation are occurring in the virus.

6 Apr 2021

Can limiting the priming dose of a SARS-CoV-2 vaccine improve immunity?

Researchers from Northwestern University and the University of Rochester in the U.S. addressed this question in their study. The researchers also explored whether the vaccines administered across the world could confer sterilizing immunity while preventing severe disease and death.

6 Apr 2021

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

To date, little evidence has been documented regarding the immune responses after the onset of the symptoms or virus detection. Further, no cross-sectional studies have been conducted that define the time of infection. Thereby, no report is available that explains the relationship between the earliest immune responses to COVID-19 and temporal kinetics. New research deals with this research gap using blood transcriptomics, multiparameter flow cytometry, and T cell receptor (TCR) sequencing methods.

6 Apr 2021

Study suggests T-cells don't determine survival in severe COVID-19

In the study, which appeared on the pre-print server medRxiv, the team found that when the monkeys were reinfected, the T cell-depleted animals showed anamnestic immune responses, the enhanced reaction of the body's immune system to an antigen that is related to an antigen previously encountered.

6 Apr 2021

Novel hydrogel-based vaccine formulation shows high efficacy against SARS-CoV-2

A fascinating new preprint research paper posted to the bioRxiv* server discusses impressively high neutralizing responses elicited with a single dose of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine formulation, which could help turn the tide of the current pandemic if validated.

6 Apr 2021

Research explores sex differences in placental defenses against SARS-CoV-2 infection

A plethora of earlier studies has reported on the differences between the sexes in susceptibility to the currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as its severity. A new preprint research paper posted to the bioRxiv* server extends this to the placenta in pregnancy.

6 Apr 2021

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

T Cell News and Research

Latest T Cell News and Research

Canopy Biosciences introduces high-plex spatial biology assay for quantitative immune cell profiling

Antifungal and antidepressant drugs can effectively inhibit COVID-19 virus

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Researchers discover two new ways to treat small cell lung tumors

Cell phone GPS data helps predict energy demand more accurately

Researchers determine key protein structure that may lead to effective treatments for schizophrenia

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

High-intensity walking exercise benefits people with peripheral artery disease

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

Tissue architecture impacts the evolutionary course of cancer

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Study discovers how microcephaly and blindness may develop in Zika-infected fetuses

Natural selection and adaptation of SARS-CoV-2 in mammals

Can limiting the priming dose of a SARS-CoV-2 vaccine improve immunity?

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

Study suggests T-cells don't determine survival in severe COVID-19

Novel hydrogel-based vaccine formulation shows high efficacy against SARS-CoV-2

Research explores sex differences in placental defenses against SARS-CoV-2 infection

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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