T Cell News and Research

Latest T Cell News and Research

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Using more than 100,000 virus genome sequences uploaded in the GISAID database, researchers found around 9,000 mutations in the virus spike protein RBD.

26 Jan 2021

Anti-emetic drug offers a promising approach to treat chronic myeloid leukemia

Chronic myeloid leukemia (CML) results from a degeneration of the hematopoietic stem cells (leukemia stem cells), thereby leading to the uncontrolled formation of specific white blood cells, the so-called granulocytes.

26 Jan 2021

New NIH grant supports research on Alzheimer's disease caused by gene mutations

A new grant from the National Institute On Aging at the National Institutes of Health will support ongoing research at Rensselaer Polytechnic Institute to address Alzheimer's disease caused by gene mutations.

26 Jan 2021

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease.

26 Jan 2021

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

A new approach to mapping viral mutations that "escape" leading clinical antibodies has revealed mutations in the SARS-CoV-2 virus that allow it to evade treatments, including a single amino-acid mutation that fully escapes Regeneron's antibody cocktail.

26 Jan 2021

New discovery could lead to faster and more effective treatments for chronic health complications

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

26 Jan 2021

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

The cover for issue 1 of Oncotarget features Figure 2, "Results in clinical trials," published in "Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer" by Blagoev, et al. which reported that most metastatic cancers develop drug resistance during treatment and continue to grow, driven by a subpopulation of cancer cells unresponsive to the therapy being administered.

26 Jan 2021

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized.

26 Jan 2021

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the renowned journal Cell.

26 Jan 2021

Astrocytes might be a potential new target to better treat epilepsy

A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy.

26 Jan 2021

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Researchers have engineered an antibody that neutralizes SARS-CoV-2 with a potency that "rivals" current lead SARS-CoV-2 clinical neutralizing antibodies, and that also broadly neutralizes a range of clade 1 sarbecoviruses.

26 Jan 2021

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

A study conducted by researchers at the University of Kentucky and the Washington University School of Medicine in the USA has revealed that mutations in the proteolytic cleavage site within the S2 subunit can alter the processing of the SARS-CoV-2 spike protein, affecting viral entry into host cells.

26 Jan 2021

Drug intervention may prevent heart damage caused by chemotherapy

There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.

26 Jan 2021

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Researchers at the Erasmus Medical Centre in the Netherlands and the University of Illinois at Urbana-Champaign in the US found that SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation and that this can be prevented by using cell lines with an active serine protease-mediated entry pathway.

26 Jan 2021

T Cell News and Research

Latest T Cell News and Research

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Anti-emetic drug offers a promising approach to treat chronic myeloid leukemia

New NIH grant supports research on Alzheimer's disease caused by gene mutations

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

New discovery could lead to faster and more effective treatments for chronic health complications

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

Astrocytes might be a potential new target to better treat epilepsy

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

Drug intervention may prevent heart damage caused by chemotherapy

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Microglial cells contribute to the negative mood experienced during neurological diseases

Anchor proteins inhibit a key metabolic driver that plays critical role in cancer and neuronal diseases

Study shows several peridomestic mammal species are potential spreaders of SARS-CoV-2

Recombinant SARS-CoV-2 protein vaccine less immunogenic but more antigenic than expected

B.1.1.7 variant and healthcare workers’ travel worry

New study unravels complete sequence of DNA repair mechanism

Immunology eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Newsletters you may be interested in