T Cell News and Research

Latest T Cell News and Research

SIRT1 takes down tumors

Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1.

13 Apr 2009

Scientists uncover mimicry at the molecular level that protects genome integrity

The new study, which was published on April 12, 2009, in an advanced online edition of the journal Nature Structural & Molecular Biology, draws new parallels between the Rad60 DNA repair factor and SUMO, a small ubiquitin-like modifier, which are both essential for maintaining genome stability during replication.

13 Apr 2009

Screening to help prevent stroke in kids increases, but limited access a problem

The number of children with a certain blood disorder undergoing an ultrasound to help prevent stroke is up significantly in the past 10 years since the publication of a major study showing its benefits.

13 Apr 2009

Researchers show how PCBs may alter in utero, neonatal brain development

In three new studies - including one appearing online in the Public Library of Science - Biology (PLoS - Biology) - UC Davis researchers provide compelling evidence of how low levels of polychlorinated biphenyls (PCBs) alter the way brain cells develop.

13 Apr 2009

$Pharmacyclics starts clinical trial of novel oral Btk inhibitor for refractory B-cell non-Hodgkin's lymphoma$

Pharmacyclics starts clinical trial of novel oral Btk inhibitor for refractory B-cell non-Hodgkin's lymphoma

Pharmacyclics, Inc. has announced that it has begun treating patients in a Phase 1 dose-escalation study to evaluate the safety and tolerability of PCI-32765, an orally available, selective inhibitor of Bruton's tyrosine kinase, or Btk, as a potential treatment for patients with relapsed or refractory B-cell non-Hodgkin's lymphoma (NHL).

13 Apr 2009

Racial disparities persist in the treatment of lung cancer

Black patients suffering from lung cancer are less likely to receive recommended chemotherapy and surgery than white lung cancer patients, a disparity that shows no signs of lessening.

13 Apr 2009

Mutations that help HIV hide undermine the virus's ability to replicate

When HIV infects a cell, a complex of human immune proteins called HLA (short for human leukocyte antigen) alert killer T cells by displaying bits of the virus on the surface of the cell. The T cells recognize these HIV fragments and mobilize an attack.

13 Apr 2009

Enhancing the effects of imatinib mesylate used to treat chronic myeloid leukemia

Individuals with chronic myeloid leukemia (CML) are first treated with a drug known as imatinib mesylate.

13 Apr 2009

Gene targeting discovery opens door for vaccines and drugs

In a genetic leap that could help fast track vaccine and drug development to prevent or tame serious global diseases, DMS researchers have discovered how to destroy a key DNA pathway in a wily and widespread human parasite.

13 Apr 2009

Creating ideal neural cells for clinical use

Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation.

13 Apr 2009

Colon cancer shuts down receptor that could shut it down

Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential.

13 Apr 2009

Gene mutation the trigger for deadly melanoma

According to British researchers as many as 70% of melanoma skin cancers may be triggered by a gene mutation.

13 Apr 2009

Chinese scientists use mouse stem cells to grow new eggs

Scientists in China say by using stem cells from the ovaries of young and adult female mice they have been able to generate new eggs.

13 Apr 2009

Transplant program tops in expected one-year survival rate

Fred Hutchinson Cancer Research Center's stem-cell transplant program at the Seattle Cancer Care Alliance (SCCA) was one of only two transplant programs nationwide that consistently outperformed the expected one-year survival rate for unrelated donor transplants, according to an independent report that assessed 122 transplant centers over a five-year period.

12 Apr 2009

microRNAs manipulate cells to one day create safe embryonic-like stem cells

A team of UCSF researchers has for the first time used tiny molecules called microRNAs to help turn adult mouse cells back to their embryonic state.

12 Apr 2009

Natural heart pacemakers?

Artificial heart pacemakers have saved and extended the lives of thousands of people, but they have their shortcomings - such as a fixed pulse rate and a limited life.

12 Apr 2009

Stem cell therapy used to restore transparency in corneas

Stem cells collected from human corneas restore transparency and don't trigger a rejection response when injected into eyes that are scarred and hazy, according to experiments conducted in mice by researchers at the University of Pittsburgh School of Medicine.

12 Apr 2009

Small RNAs can play critical roles in male infertility/contraception

University of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant implications for male infertility and contraception.

12 Apr 2009

Research sheds new light on inflammatory disease

Scientists at the University of Liverpool have found that understanding the precise timing of communication between cells that coordinate the body's response to disease could be key to new drug developments.

12 Apr 2009

Synthetic green-glowing genes show how 'silent' mutations influence protein production

Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones.

12 Apr 2009