T Cell News and Research

Latest T Cell News and Research

Discovery of key protein regulator of inflammation and cell death

Reporting in the journal Nature , researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

Gene provides hope for restoring injured nerves

University of Utah scientists identified a worm gene that is essential for damaged nerve cells to regenerate, and showed they could speed nerve regeneration by over-activating the gene - a step toward new treatments for nerves injured by trauma or disease

23 Jan 2009

First '3D movie' of tumour protein gives new drug hope

First '3D movie' of tumour protein gives new drug hope CANCER RESEARCH UK scientists have created the first complete model of a molecule which captains a key cell signalling network to prevent cancer - and exposed the secret of how a highly selective drug can intervene to control its activity, according to a study published in PLoS Biology.

23 Jan 2009

Lisofylline drug improves type 2 insulin action; reduces harm of fat in preclinical study

Results of a preclinical study involving DiaKine Therapeutics' lead drug candidate Lisofylline (LSF) indicate the compound may reduce two key risk factors for type 2 diabetes.

23 Jan 2009

Topical treatment wipes out herpes with RNAi

Whether condoms or abstinence, most efforts to prevent sexually transmitted diseases have a common logic: keep the pathogen out of your body altogether.

21 Jan 2009

Discovery could lead to novel arrhythmia treatments

Abnormal heart rhythms - arrhythmias - are killers. They strike without warning, causing sudden cardiac death, which accounts for about 10 percent of all deaths in the United States.

21 Jan 2009

Slices of living human brain tissue are helping scientists identify new stroke therapies

Slices of living human brain tissue are helping scientists learn which drugs can block the waves of death that engulf and engorge brain cells following a stroke.

21 Jan 2009

Protease inhibitor found to aid diabetic retinopathy treatment

Researchers from Joslin Diabetes Center, Boston, and ActiveSite Pharmaceuticals, Inc., San Francisco, announced today that they have demonstrated that a specific inhibitor of the protease plasma kallikrein, ASP-440, developed by ActiveSite Pharmaceuticals, may provide a new therapeutic approach for treatment of diabetic retinopathy, the most common eye-related complication of diabetes.

21 Jan 2009

Oral steroids ineffective treatment for wheezing in children

A new study from Barts and The London School of Medicine and Dentistry has found that a common treatment for wheezing in preschool children is no more effective than a placebo.

21 Jan 2009

Magnesium sulphate protects babies against cerebral palsy

Giving pregnant mothers magnesium sulphate when they are at risk of very preterm birth can help protect their babies from cerebral palsy, according to an international review of research involving the University of Adelaide, Australia.

21 Jan 2009

Inflammation contributes to colon cancer

Researchers led by Drs. Lillian Maggio-Price and Brian Iritani at The University of Washington found that mice that lack the immune inhibitory molecule Smad3 are acutely sensitive to both bacterially-induced inflammation and cancer.

21 Jan 2009

Potential new target in the war on HIV/AIDS

The study revealed that a variant of a protein involved in HIV pathogenesis can suppress production of an HIV protein, known as Nef. Nef is required for the human immunodeficiency virus to develop into AIDS through a series of complex events involving viral elements and cellular proteins. Nef has never been a target for drug treatment in HIV patients.

21 Jan 2009

Researchers show how anthracycline class of chemotherapeutics block blood vessel growth, slow cancer spread

Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth.

21 Jan 2009

Topical microbicide protects against genital herpes

A topical microbicide that silences two genes can safely protect against genital herpes infection for as long as one week, according to a joint study by researchers at the Albert Einstein College of Medicine of Yeshiva University and Harvard Medical School.

21 Jan 2009

More scientific evidence supporting Darwinian views of evolution

Studies at the University of Pennsylvania School of Medicine on brain electrical signaling offer a fresh perspective on vertebrate evolution, provide additional evidence supporting Darwinian views of evolution, and may also lead to more effective treatment of epileptic seizures in infants.

21 Jan 2009

Engineered virus targets and kills apparent cancer stem cells in neuroblastoma

After identifying an apparent population of cancer stem cells for neuroblastoma, researchers successfully used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells.

21 Jan 2009

Cell transplantation and diabetes: New sites, new devices

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s.

21 Jan 2009

Cream containing tretinoin associated with death in clinical trial, but relationship does not appear causal

Patients using a cream containing tretinoin, a retinoid commonly used to treat acne and other conditions, appeared more likely to die than those using a placebo in a clinical trial that was halted early as a result, according to a report in the January issue of Archives of Dermatology.

19 Jan 2009

Researchers identify biochemical switch required for nerve cells to respond to DNA damage

The finding, scheduled for advance online publication in Nature Cell Biology, illuminates a connection between proteins involved in neurodegenerative disease and in cells' response to DNA damage.

19 Jan 2009