T Cell News and Research

Latest T Cell News and Research

The Internet stimulates and possibly improves brain function

UCLA scientists have found that for computer-savvy middle-aged and older adults, searching the Internet triggers key centers in the brain that control decision-making and complex reasoning. The findings demonstrate that Web search activity may help stimulate and possibly improve brain function.

14 Oct 2008

Design of a compound that stabilizes the main natural suppressor of tumours

An interdisciplinary team of researchers, headed by Ernest Giralt at the Institute for Research in Biomedicine (IRB Barcelona) and Javier de Mendoza at the "Institut Catala d'Investigaciió Quimica" (ICIQ, Tarragona), have discovered a substance with the capacity to maintain protein p53 stable even when it presents certain mutations that promote the appearance of cancer.

14 Oct 2008

OncoGenex achieves key regulatory milestone for lead product candidate

OncoGenex Pharmaceuticals Inc. today announced that it concluded a meeting with the U.S. Food and Drug Administration (FDA) on October 7, 2008, and that the FDA agreed that "durable pain palliation is an acceptable and desirable study endpoint" to support a product marketing approval for OGX-011 as a treatment for hormone refractory prostate cancer (HRPC).

13 Oct 2008

Unpicking the complexity of human disease

Impressive advances in our understanding of the genetic basis of disease were outlined at the 3rd ESF Functional Genomics Conference in Innsbruck, Austria.

13 Oct 2008

Study specifies chemical pathway for ions through the cell membrane

Life ultimately depends on the traffic of tiny charged particles through porous proteins studding the membrane surrounding every cell. In research published in Nature, scientists at The Rockefeller University have for the first time mapped a stepping-stone pathway of amino acids that these charged particles, or ions, follow across cell membranes.

13 Oct 2008

New maturation inhibitor drugs may help solve HIV treatment conundrum

Since AIDS was first recognized in 1981, significant advances have been made in developing an effective arsenal of drugs to manage the disease and extend patients' lives.

13 Oct 2008

5 things you should know about stem cell research

In just a few weeks, Michigan voters will have an important decision to make when casting their ballots.

13 Oct 2008

New properties of skin stem cells

Recent research from the Swedish medical university Karolinska Institutet reveals completely new properties of the skin's stem cells - discoveries that contradict previous findings.

13 Oct 2008

Scientists image transfer of antibodies from mother's milk, to baby's gut

The transportation of antibodies from a mother to her newborn child is vital for the development of that child's nascent immune system. Those antibodies, donated by transfer across the placenta before birth or via breast milk after birth, help shape a baby's response to foreign pathogens and may influence the later occurrence of autoimmune diseases.

13 Oct 2008

Kinaxo partners with Boehringer Ingelheim

Kinaxo Biotechnologies GmbH announced today that it has entered into a two-year collaboration with Boehringer Ingelheim. Under the agreement Kinaxo will apply its new platform technologies to studies on drug mode of action and target identification. Financial details of the agreement were not disclosed.

13 Oct 2008

Link found between mitochondria and tumor formation in stem cells

Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors.

12 Oct 2008

Quark Pharmaceuticals' siRNAs examined alone and in xombination with chemotherapy

Quark Pharmaceuticals, Inc. has announced that the journal Cancer Research published results on efficacy of siRNA targeting its proprietary target gene against non-small cell lung cancer (NSCLC) in the edition dated October 1, 2008.

12 Oct 2008

Landmark study unlocks stem cell, DNA secrets to speed therapies

In a groundbreaking study led by an eminent molecular biologist at Florida State University, researchers have discovered that as embryonic stem cells turn into different cell types, there are dramatic corresponding changes to the order in which DNA is replicated and reorganized.

12 Oct 2008

Statins may prevent miscarriages in antiphospholipid syndrome

Hospital for Special Surgery researchers have found that statins may be able to prevent miscarriages in women who are suffering from pregnancy complications caused by antiphospholipid syndrome (APS), according to a study in mice.

12 Oct 2008

Body's built-in weapon against HIV explained

Humans have a built-in weapon against HIV, but until recently no one knew how to unlock its potential.

12 Oct 2008

Ultra-sensitive nanoprobes help tackle MRSA

This week Nature Nanotechnology journal (October 12th) reveals how scientists from the London Centre for Nanotechnology (LCN) at University College London are using a novel nanomechanical approach to investigate the workings of vancomycin, one of the few antibiotics that can be used to combat increasingly resistant infections such as methicillin-resistant Staphylococcus aureus (MRSA).

12 Oct 2008

FDA approves second-generation TAXUS Liberte Paclitaxel-Eluting Coronary Stent System

Boston Scientific Corporation has announced it has received approval from the U.S. Food and Drug Administration (FDA) to market its second-generation TAXUS Liberte Paclitaxel-Eluting Coronary Stent System.

12 Oct 2008

Reason for body's response to borrelia discovered

Inside a cell it is so crowded that a certain protein from borrelia winds up being crunched. From having been like an oblong rugby football, it gets bent and then collapses into a lump. At this point a previously hidden part appears, known to trigger the formation of antibodies. This explains how Borrelia can be diagnosed, a process that was previously unknown.

12 Oct 2008

Tracking down the cause of Mad Cow disease - first synthetic prion protein with an anchor

The cause of diseases such as BSE in cattle and Creutzfeld-Jakob disease in humans is a prion protein. This protein attaches to cell membranes by way of an anchor made of sugar and lipid components (a glycosylphosphatidylinositol, GPI) anchor. The anchoring of the prions seems to have a strong influence on the transformation of the normal form of the protein into its pathogenic form, which causes scrapie and mad cow disease.

12 Oct 2008

On the trail of a targeted therapy for blood cancer

Investigators from the Herman B Wells Center for Pediatric Research at the Indiana University School of Medicine are focusing on a family of blood proteins that they hope holds a key to decreasing the toxic effects of chemotherapy in children and adults.

12 Oct 2008