T Cell News and Research

Latest T Cell News and Research

New understanding of sphingosine kinases called SphK1 and SphK2

Virginia Commonwealth University Massey Cancer Center researchers have found that two enzymes that catalyze the same reaction and produce the same product have opposite effects on cell growth and death.

7 Nov 2005

Gene silencing and microRNA discovery

One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs.

7 Nov 2005

Vaccine that targets nicotine rather than the brain's reaction to it

Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. Today, it is still the leading cause of cancer-related deaths, with totals more than the other five leading cancers combined.

3 Nov 2005

Stem cells appear to play a role in repairing organs

Not least because undifferentiated cells with features typical of stem cells are being increasingly found in organs like the liver, brain, and muscles, scientists are beginning to assume that these cells play a role in repairing organs.

3 Nov 2005

Women show a better response to lung cancer therapy, resulting in better survival rates

However, in untreated patients, women also had a 21 percent decreased risk of death as compared with men, leading researchers to believe lung cancer in women has a different biologic behavior and natural history than in men.

3 Nov 2005

Neurological and neuromuscular diseases raise risk of complications from flu

As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza.

3 Nov 2005

Neuron finding could advance understanding of epilepsy and age-related memory loss

Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin in a new study that highlights the important role that these cell regions may play in the processes of learning and memory.

3 Nov 2005

Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

Fundamental insight about protein evolution

While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.

3 Nov 2005

New method to find deadly malaria parasite

Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms

3 Nov 2005

New insight into the eradication of HIV in infected individuals receiving antiviral therapy

Antiviral therapy has been used to suppress HIV replication and has dramatically improved the clinical course of disease in affected patients. But the existence of viral reservoirs precludes the complete elimination of HIV from treated patients.

3 Nov 2005

Combination of radiotherapy and a drug named S247 as a cure for cancer

Does a combination of radiation therapy and the inhibition of integrins (key molecules in angiogenesis) improve the chance of cure in cancer?

3 Nov 2005

Cancer Vaccine - Synthetically generated glycopeptides from tumor cells can stimulate the formation of specific antibodies

Tumor cells and healthy somatic cells differ in the structures on their surfaces. In principle, it should thus be possible to develop a vaccine that causes a patient’s immune system to form antibodies that attack and destroy tumor cells while sparing healthy cells.

3 Nov 2005

"Screen and treat” cervical cancer programs effective in poorly resourced areas

According to a new study two "screen and treat" cervical cancer prevention programs developed for high-risk women in low-resource settings resulted in a lower prevalence of precancerous cervical lesions and cervical cancer, according to a study in the November 2 issue of JAMA: The Journal of the American Medical Association.

2 Nov 2005

Bush wants $7bn to fight bird flu

U.S. president George Bush has called on Congress to approve $7.1 billion in emergency spending to pay for a strategy to prepare America for the danger of a pandemic bird flu outbreak.

2 Nov 2005

Desperate patients cause stem cell web site to crash

The web site of South Korea's new stem cell bank has crashed even before it began taking applications to take part in research.

2 Nov 2005

Protein called CHIP helps untangle protein misfolding in brain disease

Keeping the body and mind healthy depends on keeping cells healthy and functioning. This means that cells need a very robust quality-control system to repair or remove damaged or misshapen proteins. Protein handling is especially important in neurons because damage or death of brain cells causes neurological disease.

1 Nov 2005

New way to generate genetically altered influenza virus

In the event of an influenza pandemic, the world's vaccine manufacturers will be in a race against time to forestall calamity.

1 Nov 2005

Potential new targets for antibiotics

A new study of genetic changes in bacteria may ultimately help drug makers stay a step ahead of disease-causing bacteria that can become resistant to antibiotics.

1 Nov 2005

Researchers determine how Tsg101 gene controls cellular growth

Researchers at Emory University School of Medicine and their colleagues have discovered a genetic mechanism that controls cellular growth in the fruit fly Drosophila melanogaster, and believe it likely that a similar system may be at work in normal and cancerous human cells.

1 Nov 2005