T Cell News and Research

Latest T Cell News and Research

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Exercise helps recovery after chemotherapy for breast cancer

Exercise after chemotherapy for breast cancer boosted the activity of infection-fighting T cells in women who worked out regularly, according to data from a study conducted at Penn State University under the direction of Andrea Mastro, professor of microbiology and cell biology.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Researchers explain how ubiquitin function is determined

University of Maryland researchers have explained, for the first time, why the linkage between the cell-regulating protein molecules called ubiquitins determines their function.

10 Jun 2005

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

The finding, reported in the June 9 issue of Science Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world.

9 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Molecule called Smad7 may open doors to future treatments in pancreatic and other forms of cancer

Making new strides in their ongoing effort to understand mechanisms behind the relentless growth of cancer cells, researchers at Dartmouth Medical School have found a promising key that may open doors to future treatments in pancreatic and other forms of cancer.

9 Jun 2005

Patients with cancer of the esophagus benefit from new technique developed by OHSU surgeons

Surgeons at the Oregon Health & Science University Digestive Health Center have developed a new technique that makes feasible and safe a potentially lifesaving and noninvasive surgical procedure known as laparoscopic esophagectomy.

9 Jun 2005

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June issue of Developmental Cell, Shai Shaham, Ph.D., and graduate student Elliot Perens use the roundworm, C. elegans, to investigate the mysterious glial cell, which makes up 90 percent of the human brain and, when it malfunctions, can contribute to diseases like Parkinson's disease and schizophrenia.

9 Jun 2005

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

MDA grantee Christian Lorson at the University of Missouri was on a team that found that exposing cells carrying a mutation that causes spinal muscular atrophy (SMA) to drugs in the aminoglycoside family helps them produce more of the needed SMN protein, a lack of which leads to SMA.

9 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

Lorus Therapeutics receives patent allowance to protect novel anticancer drug

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc. (GeneSense), has received notice from the European Patent Office of its intention to grant GeneSense's application for a patent of its novel antisense drug, GTI-2501.

9 Jun 2005

MabThera highly effective in treating rheumatoid arthritis

Results from the DANCER study presented today revealed that MabThera significantly improves symptoms in heavily treated patients who are affected by moderate-to-severe rheumatoid arthritis (RA), a painful and debilitating disease of the joints.

9 Jun 2005

Rituximab, used to treat rheumatoid arthritis (RA) is safe and effective

Professor Paul Emery from the University of Leeds in the UK led the DANCER study (Double blind placebo controlled dose ranging study), designed to confirm the efficacy of rituximab for the treatment of patients with active RA who have failed to improve on one or more disease modifying anti-rheumatic drugs (DMARDs).

9 Jun 2005

MicroRNAs play an important role in human cancer

Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer. The findings are published in today's issue of the journal Nature (June 9).

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

Researchers link aberrant 'microRNA' expression to human cancer

8 Jun 2005

Canada's first two human embryonic stem cell lines

A senior scientist at Mount Sinai Hospital has developed Canada's first two human embryonic stem cell lines, giving researchers across the country new potential and hope for eventually discovering treatments and cures for many chronic and fatal diseases.

8 Jun 2005

Several minute intermediate stage in virus-cell fusion may represent a window of opportunity for drug development

To ignite a life-threatening infection in the body, a virus such as HIV invades body cells by first merging, or fusing, with the cell's outer membrane. Once inside the cell, the invading microbe's genetic material takes over, turning the 'host' cell into a factory to produce more copies of the virus, which then spill out to invade other cells in the body.

8 Jun 2005

T Cell News and Research

Latest T Cell News and Research

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

DNA discovery may help explain disorders such as autism

Exercise helps recovery after chemotherapy for breast cancer

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers explain how ubiquitin function is determined

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

Molecule called Smad7 may open doors to future treatments in pancreatic and other forms of cancer

Patients with cancer of the esophagus benefit from new technique developed by OHSU surgeons

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

Research opens up new directions for studying prion diseases in humans

Lorus Therapeutics receives patent allowance to protect novel anticancer drug

MabThera highly effective in treating rheumatoid arthritis

Rituximab, used to treat rheumatoid arthritis (RA) is safe and effective

MicroRNAs play an important role in human cancer

New study shows tiny RNAs intimately associated with cancer

Researchers link aberrant 'microRNA' expression to human cancer

Canada's first two human embryonic stem cell lines

Several minute intermediate stage in virus-cell fusion may represent a window of opportunity for drug development

Immunology eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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