T Cell News and Research

Latest T Cell News and Research

Research suggests a central role for NMDA receptors in learning and memory

Learning and memory are processes that link experience with behavior and therefore play central roles in our daily experience. That there exists a physical basis for these processes seems at first hard to imagine--except for the fact that physical disruptions in the brain, such as stroke or disease, can make them go wrong.

11 Apr 2005

Ephrins may influence learning

A Burnham Institute study has found that one of the cell's largest families of signaling molecules, called ephrins, which are known to regulate the development of nerve cells, also controls nerve cells' ability to engulf critical chemicals and proteins for learning and memory.

11 Apr 2005

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

A team of scientists from Colombia, the United States and elsewhere has successfully completed a 15-year-plus search for the genetic problems behind the very rare Roberts syndrome, whose physical manifestations often include cleft lip and palate and shortened limbs that resemble those of babies whose mothers took thalidomide during pregnancy.

11 Apr 2005

Novel human kidney protein called renalase that regulates both heart contraction and blood pressure

Researchers at Yale School of Medicine and the VA Connecticut Healthcare System in West Haven identified a novel human kidney protein called renalase that regulates both heart contraction and blood pressure; it is a strong candidate for easily administered treatment of advanced kidney and cardiovascular disease.

10 Apr 2005

Assessing the function of unknown genes is feasible and can be done with a microarray phenotype

Microarrays provide a method of quantifying the expression and order of genes in a particular genome -- acting as a surrogate measure of cell physiology, said researchers at Baylor College of Medicine in a report that appears online today in the journal Nature Genetics.

10 Apr 2005

Findings will stir new research in bacterial evolution

Bacteria acquired up to 90 percent of their genetic material from distantly related bacteria species, according to new research from The University of Arizona in Tucson.

7 Apr 2005

New technology and treatments for heart and lung patients drive revisions

The process for prioritizing heart and lung transplant candidates and determining the treatments they receive while awaiting donor organs is under review by the International Society for Heart and Lung Transplantation (ISHLT) during its Annual Meeting and Scientific Session this week in Philadelphia.

7 Apr 2005

Researchers shed light on the brain cell damage caused by Alzheimer's disease

The researchers hope that by gaining a better understanding of the disease's cellular impacts, progress can be made towards developing a treatment. The research is reported in the current edition of the Journal of Alzheimer's Disease, published by IOS publishers.

7 Apr 2005

Molecular motors cooperate in moving cellular cargo

Researchers using an extremely fast and accurate imaging technique have shed light on the tiny movements of molecular motors that shuttle material within living cells. The motors cooperate in a delicate choreography of steps, rather than engaging in the brute-force tug of war many scientists had imagined.

7 Apr 2005

Research helps understand how the malaria parasite disguises itself to avoid detection by the immune system

Scientists are making strides in understanding how the malaria parasite Plasmodium falciparum disguises itself to avoid detection by the immune system. The findings could lead to the development of new drugs for a disease that causes more than 300 million acute illnesses and at least one million deaths each year, most of them in developing countries.

7 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Fibril shape is the basis of prion strains and cross-species prion infection

New research on prions, the infectious proteins behind "mad cow" disease and Creutzfeld-Jakob disease in humans, suggests that the ability of prions in one species to infect other species depends on the shape of the toxic threadlike fibers produced by the prion. Two studies on the topic appear in the 8 April issue of the journal Cell.

7 Apr 2005

Process called sumoylation regulates key ion channel

Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs.

7 Apr 2005

Epstein-Barr virus may increase risk of lupus

Almost everyone has been infected with Epstein-Barr virus (EBV), a member of the herpes family and one of the most common human viruses.

7 Apr 2005

Potential therapeutic target for treating Huntington's disease

Researchers studying yeast cells have identified a metabolic enzyme as a potential therapeutic target for treating Huntington's disease, a fatal inherited neurodegenerative disorder for which there is currently no effective treatment. The group, whose results appear in the May issue of Nature Genetics, includes researchers from the University of Washington School of Medicine in Seattle and the University of Maryland School of Medicine in Baltimore.

6 Apr 2005

Asthmatics naturally deficient in antiviral immunity

Asthmatics produce lower levels of a type of immune cell protein needed to fight off infection from colds and other viruses, scientists have discovered.

6 Apr 2005

Startling evidence that people can unconsciously learn complex motor behaviors by watching

It's widely accepted that people watching an expert golfer or carpenter can learn the procedural steps to a better golf swing or building a deck. However, researchers Andrew A.G. Mattar at McGill University and Paul L. Gribble of the University of Western Ontario have developed startling evidence that people can unconsciously learn complex motor behaviors by watching such performances.

6 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

Sensory deprivation reduces new cell size in the olfactory system

Sensory deprivation causes changes in new cell size and excitability in the olfactory system, which governs the ability to smell, according to a study in Neuron by a Yale School of Medicine researcher.

6 Apr 2005

Yeast discovery provides new insights into familial dysautonomia

A discovery in yeast that has important implications for finding a cure for a devastating disease of nerve cell failures -- called familial dysautonomia (FD) -- has been made by Cornell University researchers.

6 Apr 2005