T Cell News and Research

Latest T Cell News and Research

Fasting every other day, while cutting few calories, may reduce cancer risk

New research at the University of California, Berkeley, raises such a possibility. It shows that healthy mice given only 5 percent fewer calories than mice allowed to eat freely experienced a significant reduction in cell proliferation in several tissues, considered an indicator for cancer risk.

15 Mar 2005

Link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein

Researchers at the University of Pennsylvania School of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers.

15 Mar 2005

New immunotherapeutic approach against anthrax

The anthrax attacks in the aftermath of September 11, 2001 in the USA have illustrated the high potential of anthrax for misuse in bio-terrorism. Dissemination of anthrax by letters led to the death of 5 people and chemotherapeutic treatment of 30,000 individuals.

15 Mar 2005

Timing is everything when it comes to killing prostate cancer cells

"The window of opportunity is narrow for vaccination, designed to reinvigorate the immune system's attack on cancer cells, and it occurs right after hormonal therapy begins to wipe out the tumor and immune cells outnumber cancerous ones," according to Charles Drake, M.D., Ph.D.

15 Mar 2005

ViaCell and Genzyme announce collaboration - ViaCell announces patent issuance

ViaCell and Genzyme Corporation announced today that the two companies entered into a collaboration related to diabetes.

15 Mar 2005

Neuronal death and processing of Tau protein in Alzheimer’s Disease (AD)

In a research report recently published in the Journal of Alzheimer's Disease, published by IOS Press, a research group from the International School for Advanced Studies (ISAS\SISSA) in Trieste (Luisa Fasulo, Gabriele Ugolini e Antonino Cattaneo) showed that a processed form of tau protein induces neuronal death by apoptosis (programmed cell death) when expressed in cultured rat hippocampal neurons.

15 Mar 2005

Process behind cellular export of iron may help to explain human hemochromatosis

The first direct evidence that a single protein is critical in the cellular export of iron may help to explain human hemochromatosis, researchers report in the March issue of Cell Metabolism.

15 Mar 2005

Most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date

A team of scientists led by Dr. Kuniya Abe from the RIKEN BioResource Center in Japan has performed one of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their findings are published in the April issue of the journal Genome Research.

15 Mar 2005

Bevacizumab (Avastin) in combination with standard chemotherapy helps advanced lung cancer sufferers

Preliminary results from a large, randomized clinical trial for patients with previously untreated advanced non-squamous, non-small cell lung cancer show that those patients who received bevacizumab (AvastinTM) in combination with standard chemotherapy lived longer than patients who received the same chemotherapy without bevacizumab.

15 Mar 2005

New insight into key mechanism by which cells limit cholesterol

The finding suggests a novel approach to the development of cholesterol-lowering drugs that may boost the effect of statins, one of the most prescribed cholesterol inhibitors, according to researchers at the University of Texas Southwestern Medical Center.

15 Mar 2005

Novel Australian anti-cancer therapy has begun safety testing in human subjects

An international medical conference here heard that an Australian developed anti-cancer therapy based on the use of a common cold virus to control cancer cell growth has begun safety testing in human subjects.

15 Mar 2005

Heart disease risk in older women identified by simple blood test

Postmenopausal women who are not identified by traditional cardiovascular risk factors, could benefit from a simple blood test to show their white blood cell (WBC) count which may predict cardiovascular events and risk of death.

15 Mar 2005

Good results in new lung cancer treatment

Interim analysis of a Phase III study of Avastin (bevacizumab) with paclitaxel and carboplatin chemotherapies in first-line non-squamous, non-small cell lung cancer (NSCLC) met its primary goal of improving overall survival, or a reduction in the risk of death, compared to chemotherapy alone.

15 Mar 2005

New cancer drug looks promising

Dr. E. Premkumar Reddy from Temple University School of Medicine and colleagues, in a study examining the effects of Plk1 inhibitor ON01910 on tumor growth in several animal models have found that a small molecule inhibitor of polo-like kinase1 (Plk1) could lead to a new avenue for targeted cancer therapy.

14 Mar 2005

$1.5 million for adult stem cell research in Australia

Australian adult stem cell company, Mesoblast Limited, today announced that its chief scientific advisor and founder, Professor Silviu Itescu, has been awarded a $1.5 million grant for pre-clinical and clinical development of mesenchymal lineage adult stem cells.

14 Mar 2005

DNA sabotage may alleviate need for chemotherapeutic medication

Johns Hopkins chemists have discovered a new way to sabotage DNA's ability to reproduce, a finding that could eventually lead to the development of new anti-cancer drugs and therapies.

14 Mar 2005

£800,000 to boost research into fighting viruses

A team of University of Glasgow scientists have received a grant of £800,000 from the Wellcome Trust to research a mechanism that blocks a critical step in the replication cycle of retroviruses. In the long term, the research could lead to the design of new therapeutic strategies or drugs against retroviruses, which cause diseases such as AIDS and certain leukemias.

14 Mar 2005

Molecule called DJ-1 is likely to be involved in the generation of human tumors

Scientists have discovered that a molecule called DJ-1 is likely to be involved in the generation of human tumors through negative regulation of the well-known tumor suppressor, PTEN. The research, published in the March issue of Cancer Cell, has important implications for determining the prognosis of some human cancers, and may prove to be a suitable target for cancer therapy.

14 Mar 2005

Seniors with giant cell arteritis are twice as likely to have a heart attack or stroke

Seniors with giant cell arteritis – a chronic inflammatory condition of medium and large arteries – are twice as likely to have a heart attack or stroke compared to adults without this condition, says new University of Toronto research.

14 Mar 2005

Simple blood test may help to predict cardiovascular risk in older women

White blood cell (WBC) count may predict cardiovascular events and risk of death in postmenopausal women who are not currently identified by traditional cardiovascular risk factors, according to an article in the March 14 issue of Archives of Internal Medicine.

14 Mar 2005