T Cell News and Research

Latest T Cell News and Research

Toxoplasma gondii discovery may help fight against malaria

University of North Carolina at Chapel Hill scientists have discovered a protein in the cell wall of parasites that’s crucial to the molecular mechanism allowing them to move between cells, survive and cause disease.

25 May 2004

Possible new second-generation multiple sclerosis therapy

Scientists from Genencor International, Inc., have demonstrated in an in vivo model that a new variant of recombinant interferon-beta reduces the immunological response to the protein.

25 May 2004

X-ray beams could kick start genes into fighting cancer

X-ray beams could kick start genes into fighting cancer as an exciting new way of targeting therapy against the disease, according to new research in the Journal of Gene Medicine.

25 May 2004

Antioxidant compound found in green tea leaves does not clear established plaque

Using a technique that enables them to study both early and advanced stages of arterial plaque buildup in the same mice, researchers at Cedars-Sinai Medical Center found that an antioxidant compound found in green tea leaves does not clear established plaque but does inhibit the development of new deposits.

24 May 2004

Researchers to develop a highly sensitive, portable method of detecting bioterror agents like anthrax

Their method uses "Cellular Analysis and Notification of Antigen Risks and Yields" (CANARY) cells, which are immune-system cells engineered to contain a fluorescent protein naturally found in jellyfish. CANARY cells have the immune system's ability to detect specific disease-causing agents, lighting up when they recognize a pathogen.

24 May 2004

Computer program to predict where DNA molecules will pop open when twisted

Biologists are used to thinking about DNA sequences as a string of letters (A, C, G, T) that happens to be arranged in an elegant double helix. But DNA also has mechanical properties that affect how genes are turned on or off, say researchers at the UC Davis Genome Center.

24 May 2004

Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment

In a small study conducted at the U.S. National Institutes of Health (NIH), researchers have shown that it may be feasible to treat HIV-infected patients with a simple, once-daily regimen of anti-HIV drugs given in pre-planned, 7-day-on, 7-day-off cycles.

24 May 2004

Researchers have isolated a protein receptor in chickens responsible for transferring antibodies from mother to offspring

Howard Hughes Medical Institute (HHMI) researchers have isolated a protein receptor in chickens that is responsible for transferring antibodies from mother to offspring - a function critical to bestowing a temporary immunity that protects the young against infection until their own immune systems begin functioning.

24 May 2004

Compound Cilantro found in salsa kills harmful Salmonella bacteria

Researchers have identified a compound in cilantro, a key flavor component of salsa and a variety of other dishes, that kills harmful Salmonella bacteria and shows promise as a safe, natural food additive that could help prevent foodborne illness, according to a joint study by U.S. and Mexican researchers.

24 May 2004

Cultured nanoparticles from filtered homogenates of diseased calcified human cardiovascular tissue

Researchers at the Mayo Clinic found they could isolate and culture nanoparticles from filtered homogenates of diseased calcified human cardiovascular tissue. These cultured nano-sized particles were recognized by a DNA-specific dye, incorporated radiolabeled uridine, and after decalcification, appeared via electron microscopy to contain cell walls.

24 May 2004

Revolutionary self healing bandage that uses the patient's own cells

A revolutionary type of 'self healing' bandage that uses the patient's own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers.

24 May 2004

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

Vertex Pharmaceuticals Incorporated has announced that it has expanded its drug discovery and development collaboration with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation.

24 May 2004

Research shows that treatment with nitric oxide after storage may dramatically improve the viability of transplanted livers

About 5,000 liver transplants are performed annually in the United States, and a key factor ensuring success is maintaining a healthy donor organ that can function effectively in the recipient. However, transplanted livers typically incur substantial damage when blood flow is restored to the organ after the transplant.

24 May 2004

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals. The discovery was made by applying the latest laboratory methods to a strain of mice restored from embryos frozen since the early 70s.

23 May 2004

An antibiotic, Tigecycline produces 74 percent cure rate in cSSSI patients

An antibiotic, currently being tested in clinical trials, produced a 74 percent cure rate for hospitalized patients with possibly life-threatening, complicated skin and skin structure infections (cSSSI).

23 May 2004

Researchers have developed technology to precisely measure the sensitivity of nerve fibers that wire up the brain during development

Through use of this technology, they discovered that these fibers, or axons, possess an incredible sensitivity to molecular guidance cues that direct the axon's route to its desired destination in the brain. Their findings are described in the June issue of Nature Neuroscience.

23 May 2004

Combination therapy may be useful in humans with spinal cord injury

A combination therapy using transplanted cells plus two experimental drugs significantly improves function in paralyzed rats, a new study shows. The results suggest that a similar therapy may be useful in humans with spinal cord injury.

23 May 2004

Using gene therapy to fight rheumatoid arthritis

Guided by a similar principle, arthritis researchers at the University of Florida and Harvard University hope to use gene therapy to help joint cells pump out a harmless protein that parks in receptor sites, leaving a notorious inflammatory agent “circling the lot” and unable to cause pain, swelling and possible joint damage.

21 May 2004

Genome research sheds light on Bardet-Biedl syndrome

By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Biedl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.

21 May 2004

Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004