T Cell News and Research

Latest T Cell News and Research

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

A research group from Slovenia, Switzerland, and Germany shows how nanoscaffolded assemblies may neutralize interaction between the SARS-CoV-2 spike protein and cell receptor, providing adequate protection in a surrogate infection assay and warranting the advance of such platforms in the pursuit for the effective vaccine.

31 Aug 2020

People with genetic risk for Alzheimer's have spatial navigation problems

An international research team headed by Anne Bierbrauer, Dr. Lukas Kunz, Dr. Carlos Gomez and Professor Nikolai Axmacher from Ruhr-Universität Bochum and Universitätsklinikum Freiburg now reports that problems in spatial navigation can also be detected in people with a genetic risk for Alzheimer's.

31 Aug 2020

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection.

31 Aug 2020

FEFU scientists to design genetically modified models for understanding malignant gliomas

Scientists of Far Eastern Federal University get started studying the formation and survival mechanisms of the brain malignant tumors cells, i.e. glioma, to reveal new ways for diagnosis and therapy for this fatal disease.

31 Aug 2020

COVID-19 patients may experience long-term cardiovascular complications

Researchers at the University of Washington in Seattle have conducted a study suggesting that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect heart tissue and contribute to whole-organ cardiac dysfunction.

31 Aug 2020

Study identifies a gene's previously unknown role in fertility

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility.

31 Aug 2020

Brain protein associated with seizures and abnormal social behaviors

A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors.

31 Aug 2020

Newly designed hydrogels allow the culture of T-cells for use in cancer immunotherapy

A team with the participation of researchers from the Spanish National Research Council has designed new hydrogels that allow the culture of T-cells or T-lymphocytes, cells of the immune system that are used in cancer immunotherapy since they have the capacity to destroy tumor cells.

31 Aug 2020

Triple therapy increases response rates in patients with Severe Aplastic Anemia

The European Society for Blood and Marrow Transplantation (EBMT), Europe's collaborative peer network of professionals working in the field of stem cell transplantation and cellular therapy, announced today the results of the phase III RACE trial during EBMTs virtual 46th Annual Meeting. Preliminary data show that adding Eltrombopag to standard immunosuppressive treatment is safe and increases response rates in patients with Severe Aplastic Anaemia.

31 Aug 2020

Alzheimer's risk and navigation problems go hand in hand

Animals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other sensory information.

31 Aug 2020

T cell epitopes from recovered COVID-19 patients identified for vaccine

A new study by researchers at The Hong Kong University of Science and Technology and published on the preprint server bioRxiv in August 2020 collates the available database of SARS-CoV-2 T cell epitopes gathered from 8 studies of COVID-19 patients who recovered. This could serve as a launchpad to fill in knowledge gaps regarding the immunological aspects of this disease, and drive towards an effective T cell vaccine.

31 Aug 2020

DeNovix launches 21 CFR Part 11 Compliance Ready software for CellDrop Automated Cell Counters

DeNovix Inc. announces the launch of EasyApps Secure, a 21 CFR Part 11 Compliance Ready software option for CellDrop Automated Cell Counters.

From DeNovix Inc. 31 Aug 2020

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

A new study by scientists in the Netherlands and published on the preprint server bioRxiv* in August 2020 shows that the severe acute respiratory coronavirus-2 (SARS-CoV-2) can infect rabbits, which opens the door for possible circulation in rabbit farms and another potential source of animal to human SARS-CoV-2 infection. This finding calls for urgent research on the prevalence of the virus in farmed rabbits.

30 Aug 2020

Using SARS-CoV-2 epitope to construct a vaccine

A new study published on the preprint server bioRxiv* in August 2020 reports the use of prediction and advanced simulation techniques to identify a novel T cell epitope on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as the basis for a customized vaccine with broad-based efficacy.

30 Aug 2020

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

However, the nucleocapsid (N) protein is also extremely abundant and, therefore, a useful target for both vaccine and diagnostic test development. A new study published on the preprint server bioRxiv in August 2020 reveals the structure of this protein, a valuable step in using it for these purposes.

30 Aug 2020

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection.

29 Aug 2020

T Cell News and Research

Latest T Cell News and Research

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

People with genetic risk for Alzheimer's have spatial navigation problems

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

FEFU scientists to design genetically modified models for understanding malignant gliomas

COVID-19 patients may experience long-term cardiovascular complications

Study identifies a gene's previously unknown role in fertility

Brain protein associated with seizures and abnormal social behaviors

Newly designed hydrogels allow the culture of T-cells for use in cancer immunotherapy

Triple therapy increases response rates in patients with Severe Aplastic Anemia

Alzheimer's risk and navigation problems go hand in hand

T cell epitopes from recovered COVID-19 patients identified for vaccine

DeNovix launches 21 CFR Part 11 Compliance Ready software for CellDrop Automated Cell Counters

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

Using SARS-CoV-2 epitope to construct a vaccine

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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