T Cell News and Research

Latest T Cell News and Research

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

By looking into zinc-finger antiviral proteins (ZAP), a new study from Germany and the United Kingdom (UK) and available on the preprint server bioRxiv suggests that zoonotic transmission of a coronavirus with a specific genetic make-up facilitated the pandemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also its sensitivity to interferons.

7 Jun 2020

Using microorganisms and their enzymes to produce minor ginsenosides

In this review article the author Almando Geraldi from the Universitas Airlangga, Indonesia considers the advances in the production of minor ginsenosides using microorganisms and their enzymes.

5 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

This spring marked a seismic shift for digestive and liver disease research at the Medical University of South Carolina with the award of more than $16.5 million in National Institutes of Health funding to open two new tightly integrated centers.

5 Jun 2020

Discovery of new killing mechanism could help design improved teixobactin-based drugs

Scientists at the University of Liverpool and University of Utrecht have taken another step forward on their quest to develop a viable drug based on teixobactin - a new class of potent natural antibiotic capable of killing superbugs.

5 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

Perchlorate in drinking water may be more dangerous than previously thought

Sometimes toxins, such as hazardous wastes and industrial byproducts, seep into groundwater, the source of our drinking water.

5 Jun 2020

Study reveals outcomes of radiosurgery for patients with brain metastases from small cell lung cancer

The international First-line Radiosurgery for Small-Cell Lung Cancer analysis led by University of Colorado Cancer Center researchers and published today in JAMA Oncology details clinical outcomes for 710 patients with brain metastases from small cell lung cancer treated with first-line stereotactic radiosurgery, without prior treatment with whole-brain radiation or prophylactic cranial irradiation.

5 Jun 2020

T cells can counteract dangerous phenomenon of mosquito-borne viruses

Every year, more than 68,000 people end up with a clinical case of Japanese encephalitis. One in four of these patients will die. The mosquito-borne virus, which is most common in Southeast Asia, also causes severe neurological damage and psychiatric disorders.

5 Jun 2020

Study offers a deeper understanding of T cell immunity in the elderly

A study by Monash Biomedicine Discovery Institute (BDI) expands the understanding of the molecular pathways that control T cell function and survival and how it relates to declining T cell immunity in the elderly.

5 Jun 2020

Researchers use single-cell-resolution technologies to map brain genes in humans

A group of scientists led by Philipp Khaitovich, a professor at Skoltech, conducted a large-scale study of gene expression in 33 different brain regions of humans, chimpanzees, macaques and bonobos using the single-cell-resolution transcriptomics technologies and made a map of the different brain regions with their specific cell structures.

5 Jun 2020

Newly identified mechanism regulates activity of nitric oxide-producing enzyme

The liver filters blood, detoxifies chemicals and metabolizes drugs. Hepatitis, alcohol and primary liver diseases are common sources of damage in the liver and can result in scarring, known as fibrosis.

5 Jun 2020

New images of LSD1 enzyme in action shed light on gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells--including cancer cells--regulate their genes.

5 Jun 2020

Antiviral effects for COVID-19: Early is better

A new study by an international team of researchers and published on the preprint server medRxiv* in June 2020 describes the possible reasons for inconsistent or null findings in clinical studies of antiviral drugs to date. It proposes a new approach to decide the sample size in light of its findings.

5 Jun 2020

New leukemia immune profiles predict drug resistance, positive responses to immunotherapy

By analyzing 442 samples from three groups of children and adults with acute myeloid leukemia (AML), researchers have identified new immune classes of the disease that predict the likelihood of drug resistance and positive responses to immunotherapy.

5 Jun 2020

Experts debate over future Parkinson’s disease trial involving growth factors

Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing.

5 Jun 2020

T Cell News and Research

Latest T Cell News and Research

Tocilizumab in COVID-19 patients on mechanical ventilation

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

Kidney enzyme renalase a potential therapy for severe COVID-19

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

Using microorganisms and their enzymes to produce minor ginsenosides

Approved drug could help dampen massive immune response associated with severe COVID-19

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

Discovery of new killing mechanism could help design improved teixobactin-based drugs

Creating hair-bearing human skin becomes a reality

GMU researchers studying effect of cannabidiol on exosome release

Perchlorate in drinking water may be more dangerous than previously thought

Study reveals outcomes of radiosurgery for patients with brain metastases from small cell lung cancer

T cells can counteract dangerous phenomenon of mosquito-borne viruses

Study offers a deeper understanding of T cell immunity in the elderly

Researchers use single-cell-resolution technologies to map brain genes in humans

Newly identified mechanism regulates activity of nitric oxide-producing enzyme

New images of LSD1 enzyme in action shed light on gene regulation

Antiviral effects for COVID-19: Early is better

New leukemia immune profiles predict drug resistance, positive responses to immunotherapy

Experts debate over future Parkinson’s disease trial involving growth factors

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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