T Cell News and Research

Latest T Cell News and Research

New clinical trial to test treatment that targets overactive immune response to COVID-19

For some COVID-19 patients, the body's immune response may be as destructive as the virus that causes the disease.

22 May 2020

Changes in antibodies and RNA shedding during early SARS-CoV-2 infection

As the COVID-19 pandemic and its far-reaching implications continue to unfold globally and disrupt our normal way of life, scientists and researchers are racing to find an appropriate vaccine or therapeutic drug. This process involves understanding how the virus interacts with the host cell, the dynamics of the host immune response, and the eventual outcome.

22 May 2020

Study to examine how stem cell transplant patients react to COVID-19 infection

A new study will look at how patients, who receive stem cell transplants for blood cancers and blood disorders, react to COVID-19 infection during their recovery.

22 May 2020

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the virus. A new study on the preprint server medRxiv* in May 2020 shows that the use of some biologically plausible drugs may be counterproductive, and care should be taken when trying out unproven therapies.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

Preparing to meet SARS-CoV-2 head-on with a panel of neutralizing antibodies

A new study published on the preprint server bioRxiv in May 2020 describes a panel of neutralizing antibodies that bind to multiple attachment sites on the spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the current COVID-19 disease pandemic.

22 May 2020

Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments

Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular "switch".

21 May 2020

A new method to monitor blood damage in real-time

According to the National Kidney Foundation, more than 37 million people are living with kidney disease.

21 May 2020

Study hints a mechanistic link between sex and stress response in microbes

Why is sex so popular? The question of why so many organisms reproduce sexually has mystified evolutionary biologists since before Darwin, who wrote that "The whole subject is as yet hidden in darkness."

21 May 2020

Distribution of human tumor mutations more similar to that of chimpanzees, gorillas

A new study by researchers from the Institute of Evolutionary Biology (IBE), a joint centre of UPF and the Spanish National Research Council (CSIC), shows that, surprisingly, the distribution of mutations in human tumours is more similar to that of chimpanzees and gorillas than that of humans.

21 May 2020

RAAS inhibitors are safe to use in COVID-19 patients, study shows

The coronavirus disease (COVID-19) is a novel illness that has spread across the globe in just five months. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral infection binds to the angiotensin-converting enzyme 2 (ACE2) to enter and invade cells.

21 May 2020

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, and Celonic Group, a premium biopharmaceutical CDMO specialized in the development and production of Advance Therapy Medicinal Products (ATMPs) and mammalian cell line-expressed biotherapeutics, today announced a collaboration to produce the novel human recombinant protein AT-100 (rhSP-D) as a therapeutic candidate against COVID-19.

21 May 2020

Excessive blood clotting and stroke in COVID-19 patients

The coronavirus disease COVID-19 is causing excessive blood clotting and stroke in young and healthy people, a new study has found.

21 May 2020

COVID-19 may damage the central nervous system

Researchers at University Hospital Düsseldorf, Germany, have provided important insights into the potential impact that coronavirus disease 2019 (COVID-19) could have on the central nervous system.

21 May 2020

Scientists create a detailed map of how carcinogens trigger breast cancer development

In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease.

21 May 2020

Study shows selenium-containing compounds inhibit SARS-CoV-2 replication and assembly

A recent paper by researchers from the Netherlands and Poland provides evidence that modified ebselen derivatives may serve as highly promising prospective drugs against coronavirus disease 2019 (COVID-19). The manuscript is freely available on the bioRxiv* preprint server.

21 May 2020

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

Computational immunology paves the way for SARS-CoV-2 peptide cocktail vaccine candidate

By employing an immunoinformatics approach, a new study available on the preprint server bioRxiv* shows how the combination of peptides designed from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid phosphoprotein and spike glycoprotein may trigger an improved immunological response with respectable safety profile, informing, in turn, further vaccine development.

21 May 2020

Cell-culture based in vitro test systems for antitumor drug screening

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

UBC scientists discover gene that plays a role in resisting weight gain

Why can some people eat as much as they want, and still stay thin?

21 May 2020

T Cell News and Research

Latest T Cell News and Research

New clinical trial to test treatment that targets overactive immune response to COVID-19

Changes in antibodies and RNA shedding during early SARS-CoV-2 infection

Study to examine how stem cell transplant patients react to COVID-19 infection

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

Preparing to meet SARS-CoV-2 head-on with a panel of neutralizing antibodies

Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments

A new method to monitor blood damage in real-time

Study hints a mechanistic link between sex and stress response in microbes

Distribution of human tumor mutations more similar to that of chimpanzees, gorillas

RAAS inhibitors are safe to use in COVID-19 patients, study shows

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Excessive blood clotting and stroke in COVID-19 patients

COVID-19 may damage the central nervous system

Scientists create a detailed map of how carcinogens trigger breast cancer development

Study shows selenium-containing compounds inhibit SARS-CoV-2 replication and assembly

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Computational immunology paves the way for SARS-CoV-2 peptide cocktail vaccine candidate

Cell-culture based in vitro test systems for antitumor drug screening

UBC scientists discover gene that plays a role in resisting weight gain

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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