T Cell News and Research

Latest T Cell News and Research

New model based on dynamic neural code can help humans to localize sounds

One of the enduring puzzles of hearing loss is the decline in a person's ability to determine where a sound originates, a key survival faculty that allows animals - from lizards to humans - to pinpoint the location of danger, prey and group members.

6 Nov 2019

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments.

6 Nov 2019

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

6 Nov 2019

Chiral interactions could be leveraged to improve the performance of drug-delivery nanoparticles

MIT engineers have shown that they can enhance the performance of drug-delivery nanoparticles by controlling a trait of chemical structures known as chirality -- the "handedness" of the structure.

6 Nov 2019

Scientists discover cell protein crucial in preventing viral replication

A research team has discovered a protein without which cells infected by viruses cannot trigger an immune response, leading to 100% mortality with even non-disease-producing strains. The discovery of the new Z-DNA binding protein, or ZBP1, was reported in the journal Frontiers in Microbiology. It could help develop new treatment methods for viruses that target the nervous system such as the Zika or West Nile Encephalitis virus.

6 Nov 2019

Study: Spherical exosomes could help in treating acute kidney injury

Like a swarm of construction workers in the aftermath of a destructive storm, cargo-filled, nanometer-sized spheres arrive on the scene following an acute kidney injury.

5 Nov 2019

New stem cell transplant lowers complications for patients with acute blood cancers

The discovery of the UM171 molecule, by Dr. Guy Sauvageau and Anne Marinier, made headlines in 2014 following an article in Science. Hailed by some as a revolution, even a miracle, in the field of blood stem cell transplantation, the UM171 molecule is delivering on its promise.

5 Nov 2019

Premature babies with bronchopulmonary dysplasia have more stem cells at birth

In the first large-scale clinical study to characterize stem cells from the umbilical cord blood and tissues of premature infants with bronchopulmonary dysplasia – a severe, chronic lung disease – researchers found that these babies had more stem cells at birth.

5 Nov 2019

UM launches CAR-T clinical trial for patients with myasthenia gravis

Neuromuscular experts with the University of Miami Health System and the Miller School of Medicine will launch a Phase 1/2 clinical trial (NCT04146051) using the CAR-T drug, Descartes-08, to treat patients with generalized myasthenia gravis.

5 Nov 2019

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

With CAR T cell therapy, a patient's own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and that they are continuing to fight disease weeks, months, or even years later?

5 Nov 2019

Researchers identify potential drug targets for glioblastoma

Researchers at Karolinska Institutet in Sweden have identified 10 tumor-specific potential drug targets for the brain tumor glioblastoma. The results are presented in the scientific journal Cell Reports.

5 Nov 2019

Tumor cell plasticity counts during cancer metastasis

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality.

5 Nov 2019

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Human Immune Monitoring Center at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo (cemiplimab-rwlc), a PD-1 antibody blockade developed by biotechnology company Regeneron Pharmaceuticals, Inc and Sanofi.

5 Nov 2019

Researchers discover new process of antitumor response of NK cells in myeloma

NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although evidence about their antitumoral capacity, how this activity occurred remained unknown.

5 Nov 2019

Mosaicism of IVF embryos does not pose any health risks to future babies

Compared to the mother's body, the egg fertilized in a test tube has rather different conditions for growing.

5 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

The use of nanoparticles to deliver a drug into specific nerve cells has resulted in significantly improved pain relief.

5 Nov 2019

Researchers find genes from 'fossil' virus in human DNA to be active

Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at the University of Washington School of Medicine and the Laval University School of Medicine in Quebec, Canada.

5 Nov 2019

One-time exposure to cannabinoids during early pregnancy can impair fetal development

A new study published in Scientific Reports, a Nature Research journal, shows how a one-time exposure during early pregnancy to cannabinoids (CBs) – both synthetic and natural – can cause growth issues in a developing embryo.

5 Nov 2019

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

The University of Texas MD Anderson Cancer Center and Takeda Pharmaceutical Company Limited today announced an exclusive license agreement and research agreement to develop cord blood-derived chimeric antigen receptor-directed natural killer (CAR NK)-cell therapies, 'armored' with IL-15, for the treatment of B-cell malignancies and other cancers.

5 Nov 2019

T Cell News and Research

Latest T Cell News and Research

New model based on dynamic neural code can help humans to localize sounds

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Chiral interactions could be leveraged to improve the performance of drug-delivery nanoparticles

Scientists discover cell protein crucial in preventing viral replication

Study: Spherical exosomes could help in treating acute kidney injury

New stem cell transplant lowers complications for patients with acute blood cancers

Premature babies with bronchopulmonary dysplasia have more stem cells at birth

UM launches CAR-T clinical trial for patients with myasthenia gravis

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

Researchers identify potential drug targets for glioblastoma

Tumor cell plasticity counts during cancer metastasis

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

Researchers discover new process of antitumor response of NK cells in myeloma

Mosaicism of IVF embryos does not pose any health risks to future babies

The Achilles heel of APC-mutated colon tumors identified

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

Researchers find genes from 'fossil' virus in human DNA to be active

One-time exposure to cannabinoids during early pregnancy can impair fetal development

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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