Thrombosis News and Research

Latest Thrombosis News and Research

Better understanding of clotting dynamics in atherosclerosis could lead to more effective drugs

The disease atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. These clots also grow until they block blood flow; in the case of the coronary artery, this can cause a heart attack.

8 Nov 2012

WU researchers to study blood-clotting disorders

Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

7 Nov 2012

Cause of heart attacks or strokes may be different in some patients treated with anti-platelet drugs

The cause of heart attacks or strokes among some patients treated with anti-platelet drugs may be different than for patients who have undergone surgical procedures to restore blood flow, according to researchers at Duke Medicine.

7 Nov 2012

Scientists identify group of small molecules that interfere with polyphosphate activity

Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are currently on the market.

7 Nov 2012

Caregiver strain link to depression mediated by rumination

Caregiving strain is associated with depressive symptoms among the family members of psychiatric patients, US study results show.

6 Nov 2012

Lupus may carry pregnancy complication risk

US researchers report that women with systemic lupus erythematosus have a twofold higher risk for developing preeclampsia than women without an autoimmune disease.

6 Nov 2012

Traditional CV risk factors linked to peripheral artery disease

Smoking, Type 2 diabetes, hypertension, and hypercholesterolemia are significantly associated with the risk for clinically significant peripheral artery disease in men, with each additional factor doubling the risk, conclude US and Dutch researchers.

6 Nov 2012

Any hospice better than none at end of life

Nursing home residents with advanced dementia who receive any hospice care during the last 90 days of life receive fewer aggressive treatments and are less likely to die in hospital than their counterparts who do not receive such care, show US study results.

6 Nov 2012

Physical exercise may help preserve mobility in Parkinson’s patients

Aerobic and resistance exercise significantly improve fitness, gait speed, and muscle strength in patients with Parkinson’s disease, shows research published in the Archives of Neurology.

6 Nov 2012

Studies shake up Alzheimer’s hypotheses

Two studies in people at genetic risk for Alzheimer’s disease reveal very early changes in brain structure and function that may actually precede amyloid beta deposition.

6 Nov 2012

Workout in the catheter lab gives clues to ‘warm-up angina’

Improved coupling of vascular and ventricular circulation during exercise appears to underlie the phenomenon known as warm-up angina, a UK study shows.

6 Nov 2012

Low-dose aspirin effective at preventing serious blood clots

Low-dose aspirin is a cheap and effective way to prevent potentially deadly blood clots in the leg or the lungs in patients who have had a previous blood clot a new study shows.

6 Nov 2012

Urban outdoor aerobic training may have negative health effects

Training outside in an urban environment may not be as beneficial for a person’s health as they might hope, suggests research.

5 Nov 2012

Overweight, smoking add to rheumatoid arthritis risk

Lifestyle changes could reduce the risk for rheumatoid arthritis in patients predisposed to the condition, Dutch researchers suggest.

5 Nov 2012

Living liver donors have QoL advantage

Living liver donors have a better quality of life than the general population, show the results of a Japanese study.

5 Nov 2012

Scientists encourage genetic data sharing

Incomplete access to private databases containing vital genetic information may hinder the development of personalized medicine, say researchers.

5 Nov 2012

Neonatal TSH screening insensitive for iodine insufficiency

Measuring levels of neonatal thyroid-stimulating hormone may not be sufficiently sensitive for inferring the extent of iodine deficiency in a given population, study results suggest.

5 Nov 2012

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Patients with rheumatoid arthritis exhibit a sub-clinical vasculitis that may underlie their increased risk for cardiovascular disease, shows research.

5 Nov 2012

Cervical cancer risk remains high after CIN treatment

Women who undergo treatment for screening-detected cervical intraepithelial neoplasia are more than four times more likely to develop cervical cancer than women with normal smear tests, research suggests.

5 Nov 2012

Sapacitabine tolerated, efficacious in elderly leukemia patients

The nucleoside analog sapacitabine appears to be “active and tolerable” in elderly patients with acute myeloid leukemia, say authors of a phase II study reported in the Lancet Oncology.

5 Nov 2012