Thrombosis News and Research

Latest Thrombosis News and Research

Scientists encourage genetic data sharing

Incomplete access to private databases containing vital genetic information may hinder the development of personalized medicine, say researchers.

5 Nov 2012

Neonatal TSH screening insensitive for iodine insufficiency

Measuring levels of neonatal thyroid-stimulating hormone may not be sufficiently sensitive for inferring the extent of iodine deficiency in a given population, study results suggest.

5 Nov 2012

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Patients with rheumatoid arthritis exhibit a sub-clinical vasculitis that may underlie their increased risk for cardiovascular disease, shows research.

5 Nov 2012

Cervical cancer risk remains high after CIN treatment

Women who undergo treatment for screening-detected cervical intraepithelial neoplasia are more than four times more likely to develop cervical cancer than women with normal smear tests, research suggests.

5 Nov 2012

Sapacitabine tolerated, efficacious in elderly leukemia patients

The nucleoside analog sapacitabine appears to be “active and tolerable” in elderly patients with acute myeloid leukemia, say authors of a phase II study reported in the Lancet Oncology.

5 Nov 2012

Smoke-free laws lead to fewer heart attacks

A recent decline in the incidence of myocardial infarction in Olmsted County, Minnesota, USA, could be due to the implementation of smoke-free laws, researchers suggest.

5 Nov 2012

Imaging-based therapy benefits ‘wake-up stroke’ patients

Undertaking thrombolysis on the basis of magnetic resonance imaging findings in patients with stroke of unknown onset time may double their chances for a good outcome, say researchers.

5 Nov 2012

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Portola Pharmaceuticals, Inc., Bristol-Myers Squibb Company and Pfizer Inc. today announced a clinical collaboration agreement to conduct a proof-of-concept study of PRT4445 and the investigational oral Factor Xa inhibitor ELIQUIS (apixaban).

3 Nov 2012

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

The U.S. Food and Drug Administration today expanded the approved use of Xarelto (rivaroxaban) to include treating deep vein thrombosis (DVT) or pulmonary embolism (PE), and to reduce the risk of recurrent DVT and PE following initial treatment.

3 Nov 2012

Radiosurgery alone can achieve local control of brain metastases

Radiosurgery to the surgical cavity without whole-brain radiotherapy achieves good rates of local control in patients with brain cancer metastases, a study has shown.

2 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

Quick-release plasters show promise for patients with sensitive skin

Scientists have developed a plaster that is strongly adhesive but easily removable, which they hope will prevent skin damage in patients with fragile skin such as neonates and the elderly.

2 Nov 2012

Breast screening saves lives but leads to overdiagnoses

Breast cancer screening leads three women to receive unnecessary treatment for every woman whose life is saved, an independent UK panel has concluded.

2 Nov 2012

$Denosumab gives FREEDOM to heal fractures$

Denosumab gives FREEDOM to heal fractures

Results from the FREEDOM trial indicate that fracture healing is not impaired in women with osteoporosis who use the antiresorptive therapy denosumab.

2 Nov 2012

UK lacks pathways through social and clinical care for eye patients

UK study results reveal that emotional and family support is lacking for individuals with visual impairment.

2 Nov 2012

TD-1211 may relieve opioid-induced constipation

TD-1211 – an inhibitor of the mµ-opioid receptor – alleviates chronic noncancer-related constipation in patients receiving opioid therapy, without affecting pain relief, show the results of a parallel-group study.

2 Nov 2012

Youth cannabis use linked to later-life anxiety disorders

Regular use of cannabis in adolescence is associated with anxiety disorders in young adulthood, shows an Australian study.

2 Nov 2012

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Affymax, Inc. and Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) today announced the presentation of post-hoc sub-group analyses of the EMERALD Phase 3 studies that evaluated OMONTYS (peginesatide) Injection, an erythropoiesis-stimulating agent (ESA), for the treatment of anemia due to chronic kidney disease (CKD) in adult dialysis patients.

2 Nov 2012