Toxicology News and Research

Latest Toxicology News and Research

Trial looks at ability of insulin to limit heart-tissue damage during a heart attack

The ability of insulin to limit heart-tissue damage during a heart attack will be tested in a landmark clinical trial led by Paresh Dandona, M.D., Ph.D., University at Buffalo Distinguished Professor in the departments of Medicine and Pharmacology and Toxicology in the UB School of Medicine and Biomedical Sciences.

13 Nov 2007

Modified Curcumin demonstrates even greater tumor suppressive properties

Curcumin, the yellowish component of turmeric that gives curry its flavor, has long been noted for its potential anti-cancer properties.

6 Nov 2007

Blood gene expression signatures predict exposure levels

In a new study, researchers found they could detect toxic levels of acetaminophen in laboratory animals by analyzing gene expression in the blood.

1 Nov 2007

What makes some clays powerful antimicrobial agents?

With funding from the National Institutes of Health-National Center for Complementary and Alternative Medicine, the UB geologists are studying the surface characteristics of a broad range of naturally occurring antimicrobial clays, including some clays from France to determine why they are such effective killers of bacteria.

29 Oct 2007

Decoding effects of toxins on embryo development

Changes in gene expression patterns in zebrafish embryos resulting from exposure to environmental toxins can identify the individual toxins at work, according to research published in the online open access journal Genome Biology.

24 Oct 2007

Ubiquitin builds up an immune response

Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination.

22 Oct 2007

Alcohol is most common 'spiking' drug

Young women in Northern Ireland are leaving themselves vulnerable to rape or serious sexual assault because of their binge drinking, according to research carried out by staff and students within the Forensic and Legal Medicine team at the University of Ulster.

15 Oct 2007

Genomic technologies to identify toxic chemicals should be developed

A new report from the National Research Council recommends that government agencies enhance their efforts to incorporate genomic data into risk assessments of chemicals and medicines, and calls for a concerted effort to fully develop these methods' potential to protect public health.

10 Oct 2007

Antibody repairs myelin in lab study of multiple sclerosis and related disorders

Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.

10 Oct 2007

Fraunhofer pharmaceutical agent speeds drug development

It takes a great deal of time and money to develop a new drug. At Biotechnica in Hanover from October 9 to 11, the Fraunhofer Life Sciences Alliance will demonstrate how a pharmaceutical agent can make its way more quickly from the research laboratory to the pharmacy.

8 Oct 2007

What our genes tell us - Identifying biomarkers for key environmental risk factors

Identifying biomarkers for the key environmental risk factors responsible for two diseases that significantly contribute to death and disease of hundreds of thousands annually will be the initial focus of a new center being established at Pacific Northwest National Laboratory.

4 Oct 2007

Gene that lowers cell stress could protect against Parkinson's disease

The discovery of a relationship between two cell enzymes and their role in keeping the cell's energy generating machinery working smoothly could provide a new target for development of therapies for Parkinson's disease (PD).

2 Oct 2007

Gene that lowers cell stress could protect against Parkinson’s disease

1 Oct 2007

Dietary fatty acids may help prevent diabetes

Omega-3 fatty acids have long been touted for their heart-healthy and brain-boosting benefits. Consider cod liver oil, fortified infant formula and enriched eggs.

27 Sep 2007

Caffeine and acetaminophen don't mix well

Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS' Chemical Research in Toxicology, a monthly journal.

27 Sep 2007

Paracetamol and coffee after a big night not such a good idea

That paracetamol along with the morning coffee after a big night may not be such a good idea after all.

27 Sep 2007

New nanoprobe imaging station helps study the distribution of elements in cells

Scientists suspect that iron accumulation plays a role in neurodegenerative processes such as Parkinson's disease, but its distribution in neurons has never been observed because of the lack of techniques to do so. Until today.

26 Sep 2007

Space flight makes bacteria more infectious

Space flight has been shown to have a profound impact on human physiology as the body adapts to zero gravity environments.

25 Sep 2007

Use of energy drinks in conjunction with alcohol popular among Italian university students

Energy drinks - known for their stimulant effects on the central nervous system - have become more and more popular among young people in recent years.

25 Sep 2007

Restricting pesticides could greatly reduce suicide rates worldwide

National and international policies restricting the pesticides that are most toxic to humans may have a major impact on world suicides, according to new research from the University of Bristol published this week in the International Journal of Epidemiology (IJE).

18 Sep 2007