2. What should I know before treatment with DBL Cisplatin Injection?
DBL Cisplatin Injection should not be used if you have ever had an allergic reaction
to cisplatin or any of the ingredients listed at the end of the CMI.
Talk to your doctor if you have kidney disease, hearing difficulties, an infection,
low blood cell production or any other medical conditions, take any other medicines,
or are pregnant or plan to become pregnant or are breastfeeding.
3. What if I am taking other medicines?
Some medicines may interfere with DBL Cisplatin Injection and affect how it works.
Examples include some medicines to treat bacterial or fungal infections, cancer, and
gout; medicine to prevent fits or to reduce the amount of water in the body; and blood
thinners, including aspirin.
4. How is DBL Cisplatin Injection given?
Your doctor will give you DBL Cisplatin Injection as a slow injection (drip) into
a vein and decide how much you will be given and for how long.
5. What should I know during treatment with DBL Cisplatin Injection?
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Things you should do
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Inform your doctor immediately if you are pregnant or experience certain side effects.
Remind any doctor, nurse, dentist, surgeon, anaesthetist or pharmacist you visit that
you are being treated with DBL Cisplatin Injection.
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Driving or using machines
|
Be careful until you know how DBL Cisplatin Injection affects you.
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Drinking alcohol
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Alcohol should be avoided because of the increased risk of bleeding in the mouth,
throat, stomach and gut.
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Looking after your medicine
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The hospital will store and dispose of the medicine.
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6. Are there any side effects?
Side effects include sudden life-threatening allergic reactions (shortness of breath,
wheezing or difficulty breathing, flushing, swelling of the face, lips, tongue or
other parts of the body, rash, itching or hives on the skin); infection (fever, fatigue,
chills, a sore throat, aches and pains, or coughing); severe nausea and vomiting;
reduced urination, joint pain, swelling of feet or lower legs, pain in the lower back
or side; headache, seizures, slurred speech and loss of memory, confusion; eye pain,
blurring or other changes in your vision; problems with movement or reduced reflexes,
and leg weakness; paralysis or numbness of the face, arm or leg, tingling or a loss
of sensation in the hands or feet; unusual bleeding such as bleeding gums, blood in
urine/wee or bowel motions/poo, unusual bruising or pinpoint red spots on the skin;
changes in the rhythm or rate of the heartbeat, tightness or pain of the chest, neck,
back or arms; shortness of breath, chest pain or coughing, yellowing of the skin,
eyes or mouth, dark urine.
Active ingredient(s): cisplatin
Full Consumer Medicine Information (CMI)
This leaflet provides important information about using DBL Cisplatin Injection. You should also speak to your doctor, nurse or pharmacist if you would like further
information or if you have any concerns or questions about using DBL Cisplatin Injection.
Where to find information in this leaflet:
1. Why am I being treated with DBL Cisplatin Injection?
DBL Cisplatin Injection contains the active ingredient cisplatin. DBL Cisplatin Injection is a type of medicine called an anti-neoplastic or cytotoxic
agent. You may also hear it referred to as chemotherapy. Cisplatin blocks DNA production
in cancer cells which helps to weaken and destroy them. It may be used alone or in
combination with other anti-cancer therapies.
DBL Cisplatin Injection is used to treat testicular cancer, ovarian cancer, bladder
cancer and cancers of the head and neck.
2. What should I know before treatment with DBL Cisplatin Injection?
Warnings
DBL Cisplatin Injection should not be used if you have:
an allergy to cisplatin, other platinum containing compounds, or any of the ingredients
listed at the end of this leaflet
kidney problems
hearing problems
reduced amounts of red or white blood cells or platelets
any infection
if you are pregnant or breast feeding.
Check with your doctor if you:
have or have had low iron levels
have heart problems
will require dental work or an invasive medical procedure
have low magnesium or calcium levels
are going to be given a vaccine
have been exposed to an infection recently, especially chicken pox or shingles
have muscle numbness or weakness, or seizures
have liver problems.
During treatment, you may be at risk of developing certain side effects. It is important
you understand these risks and how to monitor for them. See additional information
under Section
6. Are there any side effects?
Pregnancy and breastfeeding
Check with your doctor if you or are pregnant or you or your partner intend to become
pregnant.
DBL Cisplatin Injection is potentially harmful to the fetus.
Women should use effective contraception during treatment with DBL Cisplatin Injection
and for at least 7 months after treatment.
Men should use effective contraception during treatment with DBL Cisplatin Injection
and for at least 4 months after treatment.
DBL Cisplatin Injection may affect male and female fertility. Check with your doctor
for advice on fertility preservation before you begin treatment.
Talk to your doctor if you are breastfeeding or intend to breastfeed.
DBL Cisplatin injection has been shown to pass into breast milk.
Women should not breastfeed during treatment with DBL Cisplatin Injection and for
at last 1 month after treatment.
3. What if I am taking other medicines?
Tell your doctor or pharmacist if you are taking any other medicines, including any
medicines, vitamins or supplements that you buy without a prescription from your pharmacy,
supermarket or health food shop.
Some medicines may affect or be affected by DBL Cisplatin Injection. These include:
some medicines to treat bacterial infections, e.g. gentamicin
some medicine to treat fungal infections e.g. amphotericin B
some medicine to treat cancer, e.g. ifosfamide, etoposide, paclitaxel, bleomycin
methotrexate, a medicine used to treat some forms of arthritis, psoriasis and cancer
medicine to reduce the amount of water in the body e.g. loop diuretics like furosemide
medicine to treat gout e.g. allopurinol, colchine, probenecid, sulfinpyrazone
medicine to prevent seizures/fits e.g. phenytoin
blood thinners e.g. coumarins, warfarin
lithium, used to treat bipolar disorder or schizophrenia.
Check with your doctor, nurse or pharmacist if you are not sure about what medicines,
vitamins or supplements you are taking and if these affect DBL Cisplatin Injection.
4. How is DBL Cisplatin Injection given?
How is DBL Cisplatin Injection given
You will be given DBL Cisplatin Injection as a slow injection (drip) into a vein.
How much will be given
Your doctor will decide how much DBL Cisplatin Injection you will be given and how
long you will be given it.
If you are given too much too much DBL Cisplatin Injection
As DBL Cisplatin Injection doses are carefully worked out and given by a doctor experienced
in its use and who will monitor you during treatment, it is extremely unlikely that
you will be given too much.
5. What should I know during treatment with DBL Cisplatin Injection?
Things you should do
Drink plenty of water prior to and after your treatment with DBL Cisplatin injection
to ensure you are well hydrated as this may help to protect the kidneys.
Keep all of your doctor’s appointments and attend any tests as directed, as treatment
with DBL Cisplatin Injection requires your doctor to monitor your kidneys, liver,
naturally occurring chemicals in your blood and blood cells.
During treatment with DBL Cisplatin Injection you may be at increased risk of bleeding,
bruising and infection. Care should be taken to minimise cuts, impacts or exposure
to infection.
Inform your doctor immediately if you experience:
problems with your hearing or a buzzing/ringing or other noise in your ears
abnormal bruising or bleeding, including in your urine/wee, bowel motion/poo, or vomit
signs of infection such as fever or chills
signs of anaemia such as shortness of breath and dizziness
severe vomiting that will not stop
swelling of the face, wheezing, shortness of breath, skin rash or itchiness
chest pain
muscle spasms/cramps, which may also have numbness/tingling
problems with your vision
fits/seizures.
Discuss any dental work you feel may be required with your doctor before visiting
your dentist.
Remind any doctor, nurse, dentist, surgeon, anaesthetist, or pharmacist you visit
that you are being treated with DBL Cisplatin Injection.
Things you should not do
Avoid taking aspirin as it may increase the risk of bleeding in the mouth, throat,
stomach and gut.
Driving or using machines
Be careful before you drive or use any machines or tools until you know how DBL Cisplatin
Injection affects you.
Drinking alcohol
Alcohol should be avoided as it may increase the risk of bleeding in the mouth, throat,
stomach and gut.
Looking after the medicine
DBL Cisplatin Injection will be stored appropriately at the hospital.
Getting rid of any unwanted medicine
The hospital staff will dispose of any leftover DBL Cisplatin Injection.
6. Are there any side effects?
All medicines can have side effects. If you do experience any side effects, most of
them are minor and temporary. However, some side effects may need medical attention.
See the information below and, if you need to, ask your doctor or pharmacist if you
have any further questions about side effects.
Side effects
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Side effects
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What to do
|
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hiccups
diarrhoea
loss of appetite, weight loss
hair loss, especially of the scalp
feeling tired or weak
loss of taste
aches or pains
red, raised or itchy skin rash
sore mouth or mouth ulcers
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Speak to your doctor if you have any of these less serious side effects and they worry
you.
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abnormal paleness, or lack of colour of the skin
shaking or tremors, foot spasms, muscle cramps or twitching
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Speak to your doctor as soon as possible if you notice any of these side effects.
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signs of an allergic reaction such as shortness of breath, wheezing or difficulty
breathing; flushing; swelling of the face, lips, tongue or other parts of the body;
rash, itching or hives on the skin; dizziness or light-headedness
signs of an infection such as a fever, fatigue, chills, a sore throat, aches and pains
or coughing
pain, swelling, or redness around the injection site
bursts of pain that run down the back into the arms and legs
severe nausea and vomiting,
reduced urination, joint pain, swelling of feet or lower legs, pain in the lower back
or side,
headache, seizures, slurred speech and loss of memory, confusion
problems hearing or ringing or abnormal sounds in the ears
eye pain, blurring or other changes in your vision
problems with movement or reduced reflexes, and leg weakness
paralysis or numbness of the face, arm or leg, tingling or a loss of sensation in
the hands or feet
unusual bleeding such as bleeding gums, blood in urine or stools, unusual bruising
or pinpoint red spots on the skin
changes in the rhythm or rate of the heartbeat, tightness or pain of the chest, neck,
back or arms
shortness of breath, chest pain or coughing
yellowing of the skin, eyes or mouth, dark urine/wee
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Call your doctor straight away, or go straight to the Emergency Department at your
nearest hospital if you notice any of these serious side effects.
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Tell your doctor or pharmacist if you notice anything else that may be making you
feel unwell.
Other side effects not listed here may occur in some people.
Some of these side effects can only be found when your doctor does tests from time
to time to check your progress.
Reporting side effects
By reporting side effects, you can help provide more information on the safety of
this medicine.
Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.
7. Product details
This medicine is only available with a doctor's prescription.
What DBL Cisplatin Injection contains
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Active ingredient
(main ingredient)
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Cisplatin
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Other ingredients
(inactive ingredients)
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Mannitol
Sodium chloride
Water for injections
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This medicine should not be used if you are allergic to any of these ingredients.
DBL Cisplatin Injection does not contain lactose, sucrose, gluten, tartrazine or other
azo dyes.
What DBL Cisplatin Injection looks like
DBL Cisplatin Injection is a clear colourless to pale yellow solution (AUST R 47275
and AUST R 47276).
Who distributes DBL Cisplatin Injection
Pfizer Australia Pty Ltd
Sydney NSW
Toll Free Number: 1800 675 229
This leaflet was prepared in September 2025.