Cabergoline 500 microgram
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Dostinex. It does not contain all
the available information. It does not take the place of talking to your doctor or
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
Dostinex against the expected benefits.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Dostinex is used for
Dostinex may be prescribed by your doctor to reduce your body's level of a hormone
known as prolactin. Dostinex may be needed if your levels of prolactin are abnormally
Abnormally high prolactin may cause menstrual changes in women, impotence in men and
breast changes in both sexes.
Dostinex can also be prescribed to prevent the production of milk in women after birth,
if breast-feeding is to be prevented for medical reasons.
Ask your doctor if you have any questions about why this medicine has been prescribed
Your doctor may have prescribed it for another reason.
Dostinex is available only with a doctor's prescription.
Before you start to take Dostinex
Before starting treatment with Dostinex, your doctor will need to do some tests to
detect any underlying heart, lung or kidney disease.
These tests include chest x-rays, physical examinations, blood tests and heart monitoring.
Your doctor will repeat these tests regularly if you are taking Dostinex for a long
period of time.
While you are taking Dostinex report anything unusual to your doctor such as difficulty
in breathing, chest pain, swelling of your hands or feet, or anything else that is
making you feel unwell.
When you must not take it
Do not take Dostinex if you have an allergy to:
any medicine containing cabergoline
any of the ingredients listed at the end of this leaflet
ergot alkaloids (medicines used to treat migraine).
Some of the symptoms of an allergic reaction may include shortness of breath, wheezing
or difficulty breathing; swelling of the face, lips, tongue or other parts of the
body; rash, itching or hives on the skin.
Do not take Dostinex if you have or have had:
any scarring or thickening of the lungs with shortness of breath
heart valve disorder
any swelling or inflammation around the heart or lungs
any abnormal formation of tissue outside the stomach wall.
Do not take this medicine if you are pregnant.
It may affect your developing baby if you take it during pregnancy.
Do not give this medicine to a child under the age of 16 years.
The safety and effectiveness in children has not been established.
Do not take this medicine after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you have or have had any of the following medical conditions:
kidney, heart and liver problems
lung disease or problems with your breathing
Raynaud's syndrome (associated with extreme numbness, tingling and colour changes
in the fingers due to cold)
ulcer or bleeding in the stomach or intestines
low blood pressure
high blood pressure after childbirth
history of severe mental illness.
Tell your doctor if you are pregnant or plan to become pregnant.
Your doctor can discuss with you the risks and benefits involved. It is recommended
that women who plan to become pregnant stop taking Dostinex at least one month before
Tell your doctor if you are breast-feeding or intend to breastfeed.
This medicine prevents the flow of breast milk.
If you have not told your doctor or pharmacist about any of the above, tell them before
you start to take Dostinex.
Taking other medicines
Tell your doctor if you are taking any other medicines, including medicines you buy
without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and Dostinex may interfere with each other. These include:
medicines used to treat mental illness, e.g. antipsychotic medicines for schizophrenia
medicines used to treat high blood pressure
ergot alkaloids, medicines used to treat migraine
medicines used to prevent nausea and vomiting (e.g. metoclopramide)
medicines called macrolide antibiotics which are used to treat bacterial infections
These medicines may be affected by Dostinex or may affect how well it works. You
may need different amounts of your medicine or you may need to take different medicines.
Your doctor or pharmacist has more information on medicines to be careful with or
avoid while taking Dostinex.
How to take Dostinex
Follow all directions given to you by your doctor or pharmacist carefully.
The directions given to you by your doctor or pharmacist on how to take Dostinex may
differ from the information contained in this leaflet. You may be given a different
dosage depending on your condition or how you react to the medicine.
If you do not understand the instructions on the label, ask your doctor or pharmacist
How much to take
To treat high levels of prolactin (hyperprolactinaemia), the recommended starting
dose is half a tablet taken twice a week. Your doctor will generally start you on
a low dose and may gradually increase your dose.
To prevent the production of breast milk, the recommended dose is two tablets taken
as a single dose, on the first day after delivery of your baby.
How to take it
Swallow Dostinex tablets with a glass of water.
When to take it
Take your medicine with food or a meal.
How long to take it
Continue taking Dostinex until your doctor tells you to stop.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to.
Otherwise, take it as soon as you remember, then go back to taking your medicine as
you normally would.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, speak to your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some
If you take too much (overdose)
Immediately telephone your doctor or the Poisons Information Centre for advice (in
Australia telephone 13 11 26, in New Zealand telephone 0800 POISON or 0800 764 766)
or go to the Accident and Emergency department (Casualty) at your nearest hospital
if you think you or anyone else may have taken too much Dostinex. Do this even if
there are no signs of discomfort or poisoning.
You may need urgent medical attention. Keep telephone numbers for these services
handy. Have the medicine or this leaflet available to give details if needed.
The symptoms of taking too much Dostinex may include nausea, vomiting, stomach pains
While you are taking Dostinex
Things you must do
Follow your doctor's requests for tests and report anything unusual to your doctor
such as difficulty in breathing, chest pain or swelling of your hands or feet.
Keep all of your doctor's appointments while taking Dostinex so that your progress
can be checked.
It is important that your doctor carries out some regular tests if you are taking
Dostinex for a long period of time to make sure the medicine is working and to prevent
unwanted side effects. These tests may include chest x-rays, physical examinations,
blood tests and heart monitoring.
If you are about to be started on any new medicine, remind your doctor and pharmacist
that you are taking Dostinex.
Tell any other doctors, dentists, and pharmacists who treat you that you are taking
Use barrier methods of contraception, such as condoms, to prevent pregnancy during
and for at least one month after taking Dostinex.
Your doctor may recommend routine pregnancy tests during long periods of treatment.
Stop taking Dostinex immediately if you become pregnant and consult your doctor.
Things you must not do
Do not use Dostinex to treat any other medical complaints unless your doctor tells
Do not stop taking your medicine until your doctor tells you to, even if you are feeling
Do not give Dostinex to anyone else, even if they have the same condition as you.
Things to be careful of
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get
Be careful driving or operating machinery until you know how Dostinex affects you.
Dostinex may cause dizziness or affect your ability to respond quickly.
If you feel sleepy while taking Dostinex, do not drive or operate machinery.
See your doctor if you notice changes in your behaviour that result in a strong desire
to either gamble, shop, eat or use medicines to excess, or you notice an increase
in your sex drive.
Such compulsive behaviours have been seen with this class of medicine, including cabergoline.
Tell your doctor as soon as possible if you do not feel well while taking Dostinex,
even if you do not think the problems are connected with the medicine or they are
not listed in this leaflet.
Like many medicines, Dostinex may cause side effects. If they occur, they are likely
to be minor and temporary. However, some may be serious and need medical attention.
It can be difficult to tell whether side effects are the result of taking Dostinex,
effects of your condition or side effects of other medicines you may be taking. For
this reason it is important to tell your doctor of any change in your condition.
Do not be alarmed by the following list of possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist about any questions you may have.
Tell your doctor if...
Tell your doctor if you notice any of the following and they worry you:
nausea or vomiting
abdominal pain, or heartburn or pain in the stomach
weakness or tiredness
temporary impairment of vision
The side effects listed above are usually mild and short lived.
Tell your doctor as soon as possible if...
Tell your doctor as soon as possible if you notice any of the following:
irregular heart beat
leg cramps or pain in the fingers or toes
depression, feelings of deep sadness
changes in behaviour such as increased sex drive, a compelling desire to gamble, shop,
eat or take medicines
any breathing problems.
The above list includes serious side effects, which may require medical attention.
Go to hospital if...
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital,
if you notice any of the following:
chest pain with shortness of breath
sudden signs of allergy such as rash, itching or hives, swelling of the face, lips,
tongue or other parts of the body, shortness of breath, wheezing or difficulty breathing.
The above list includes very serious side effects. You may need urgent medical attention
or hospitalisation. These side effects are very rare.
Tell your doctor if you notice anything else that is making you feel unwell when you
are taking, or soon after you have finished taking Dostinex.
Other side effects not listed above may also occur in some patients.
Some of these side effects (e.g. changes in liver function) can only be found when
your doctor does tests from time to time to check your progress.
After taking Dostinex
Keep Dostinex in its container until it is time to take it.
Keep Dostinex in a cool dry place, where the temperature stays below 25 °C.
Do not store Dostinex, or any medicines, in a bathroom or near the sink. Do not leave
Dostinex in the car or on window sills.
Heat and dampness can destroy some medicines.
Keep Dostinex where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
Ask your pharmacist what to do with any Dostinex which is left over, or if the medicine
has passed its expiry date.
What it looks like
Dostinex comes as capsule-shaped, flat, white tablets. One side is marked with the
letter 'P' on a side of the score and the letter 'U' on the other. The other side
of the tablet is marked '700' with a short score on the top and bottom of the tablet
Dostinex is available in bottles of 2 and 8 tablets.
The active ingredient is cabergoline 500 microgram.
Each tablet also contains: lactose and leucine.
Dostinex tablets are supplied in Australia by:
Pfizer Australia Pty Ltd
Toll Free number: 1800 675 229
Dostinex tablets are supplied in New Zealand by:
Pfizer New Zealand Limited
PO Box 3998
Toll free number: 0800 736 363
Australian Registration Number
AUST R 52158
This leaflet was revised in October 2019.
© Pfizer Australia Pty Ltd
® Registered Trademark