Consumer Medicine Information (CMI)
What is in this leaflet
This leaflet answers some common questions about this medicine.
It does not contain all of the available information. It does not take the place of
talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking
Klacid against the benefits they expect it will have on you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
What Klacid is used for
Klacid is used to treat certain bacterial infections, including the following:
respiratory tract infections
Klacid is also used to prevent a specific bacterial infection associated with HIV
Your doctor, however, may have prescribed Klacid for another purpose. Ask your doctor
if you have any questions about why Klacid has been prescribed for you.
Klacid is an antibiotic that belongs to the group of medicines called macrolides.
These medicines work by killing or stopping the growth of bacteria which cause infections.
Klacid will not work against infections caused by viruses, such as colds or flu.
Klacid is available only with a doctor's prescription.
Klacid to treat peptic ulcer
Peptic ulcers are associated with an infection in the intestine and stomach by a bacteria
called Helicobacter pylori (H. pylori). Nearly all patients with peptic ulcers are
infected with this bacteria.
The H. pylori infection can be treated with a combination of Klacid (clarithromycin)
and other appropriate antibiotic and stomach acid control treatments. However, the
best combination of tablets to treat H. pylori infection is yet to be determined.
Your doctor will determine the best combination for you.
If your symptoms return, consult your doctor. It is possible that Klacid may no longer
be effective in killing the H. pylori infection and a different antibiotic may be
Before you take Klacid
When you must not take Klacid
Do not take Klacid if you have ever had an allergic reaction to:
medicines containing clarithromycin
other antibiotics from the macrolide family. These may include:
erythromycin (EES, Erythrocin, Eryc, E-mycin, EMU-V)
roxithromycin (Rulide, Biaxsig, Roxar)
azithromycin (Zithromax, Azith, Zedd)
any of the ingredients listed at the end of this leaflet
Some symptoms of an allergic reaction include skin rash, itching, shortness of breath
or swelling of the face, lips or tongue, which may cause difficulty in swallowing
Do not take Klacid if you have severe liver problems or poor kidney function.
Do not take Klacid if you have an irregular heartbeat.
Do not take Klacid if you have ever had a heart condition called long QT syndrome
(or QT prolongation).
Do not take Klacid if you have low potassium.
Do not take Klacid if the packaging is torn or shows any signs of tampering.
Do not take Klacid if the use by date (Exp.) printed on the pack has passed.
If it has expired or is damaged return it to your pharmacist for disposal.
Do not take Klacid if you are taking the following medicines:
astemizole or terfenadine (commonly used to treat allergy symptoms - these medicines
may be available without prescription)
cisapride (used to relieve certain stomach problems)
pimozide (used to treat schizophrenia)
ergotamine or dihydroergotamine (used to treat headaches)
lovastatin or simvastatin (used to treat high cholesterol)
ticagrelor or ranolazine (used to prevent blood clotting)
colchicine (used to treat gout)
midazolam tablets or syrup (used to produce drowsiness before certain procedures or
Before you start to take or are given Klacid:
Tell your doctor if you are pregnant or plan to become pregnant.
Your doctor will discuss the risks and benefits of taking Klacid when pregnant.
Tell your doctor if you are breastfeeding or wish to breastfeed.
Your doctor will discuss the risks and benefits of taking Klacid when breastfeeding.
Tell your doctor if you have, or have ever had, any other health problems or medical
conditions, including heart problems, liver problems or poor kidney function.
Tell your doctor if you have a slow heart rate (bradycardia) or any other heart condition.
Tell your doctor if you have low magnesium or any other electrolyte imbalances.
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you have intolerance to sugars. Tell your doctor before Klacid
oral liquid is given.
Tell your doctor if you have myasthenia gravis, a condition in which the muscles become
weak and tire easily.
If you have not told your doctor or pharmacist about any of the above, tell them before
you start taking or are given Klacid.
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you buy without a prescription from your pharmacy, supermarket or health food
Some medicines may affect the way Klacid works or may be affected by Klacid. These
include the medicines already listed under "When you must not take Klacid" (see above)
and the following medicines:
digoxin, quinidine, disopyramide (used to treat heart failure)
warfarin and other anticoagulants (used to prevent blood clotting)
phenytoin, carbamazepine, phenobarbital (phenobarbitone), sodium valproate (used to
theophylline (used to treat asthma)
triazolam, alprazolam, midazolam (used to treat sleeplessness and anxiety)
cilostazol (used to treat poor circulation)
statins such as rosuvastatin, atorvastatin (used to treat high cholesterol)
methylprednisolone (a corticosteroid)
vinblastine (used to treat cancer)
sildenafil, tadalafil, vardenafil (used to treat erectile dysfunction in adult males)
ciclosporin, tacrolimus (medicines affecting the immune system)
medicines used to treat HIV infection
rifabutin, rifampicin (used to treat some infections)
repaglinide, nateglinide, pioglitazone, rosiglitazone (used to treat diabetes)
insulin (used to treat diabetes)
calcium channel blockers such as verapamil, amlodipine, diltiazem (used to treat high
fluoxetine (used to treat depression)
omeprazole (used to treat stomach problems)
aminoglycosides (used to treat infections)
fluconazole and itraconazole (used to treat fungal infections)
tolterodine (used to treat bladder problems)
herbal medicines such as St John's Wort
These medicines may be affected by Klacid or may affect how well Klacid works. Your
doctor or pharmacist can tell you what to do if you are taking any of these medicines.
They also have a more complete list of medicines to be careful with or avoid while
How to take Klacid
Your doctor will tell you how much to take and when to take it. Take Klacid exactly
as directed by your doctor.
This may differ from the information contained in this leaflet.
How much to take
The dose of Klacid will depend on the infection to be treated.
For respiratory tract infections and skin infections, the usual adult dose is one
Klacid 250 mg tablet twice a day.
For more severe infections, the dose can be increased to one Klacid 500 mg tablet
twice a day.
For respiratory tract infections the usual dose for children is 7.5mg/kg twice a day
or as directed by your doctor. For children under 12 years of age Klacid Powder for
Oral Liquid should be used.
Your doctor will adjust the amount or frequency of your doses according to the infection
being treated and the severity of your condition.
If you do not understand the instructions on the box/bottle, ask your doctor or pharmacist
How to take Klacid
Klacid tablets should be swallowed whole with a glass of water.
Klacid Powder for Oral Liquid
Shake the bottle well and accurately measure the dose with a medicine measure.
Shaking the bottle before use
and using a medicine measure will make sure that you get the correct dose.
How long to take Klacid for
Keep taking Klacid until you finish the pack or bottle, or for as long as your doctor
If you are being treated for an infection, Klacid is usually taken for one or two
Do not stop taking Klacid, even if you feel better after a few days, unless advised
by your doctor. Your infection may not clear completely if you stop taking your medicine
Check with your doctor if you are not sure how long you should be taking Klacid.
If you forget to take it
If it is almost time for you to take your next dose, skip the dose you missed and
take your next dose when you are meant to. Otherwise, take it as soon as you remember,
and then continue taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed.
If you miss more than one dose, or are not sure what to do, check with your doctor
If you take too much (overdose)
Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26)
for advice, or go to casualty at your nearest hospital if you think that you or anyone
else may have taken too much Klacid. Do this even if there are no signs of discomfort
or poisoning. You may need urgent medical attention. Keep telephone numbers for
these places/services handy.
If you take too much Klacid, you may develop severe gastrointestinal symptoms, liver
problems, or allergic reactions.
While you are taking Klacid
Things you must do
If you are taking Klacid for an infection and your symptoms do not improve within
a few days, or if they become worse, tell your doctor.
Tell your doctor if you become pregnant while taking Klacid.
If you get severe diarrhoea, tell your doctor or pharmacist immediately.
Do this even if it occurs several weeks after stopping Klacid. Diarrhoea may mean
that you have a serious condition affecting your bowel. You may need urgent medical
care. Do not take any medicine to stop your diarrhoea without first checking with
Tell your doctor immediately if you experience any heart palpitations, changes in
heartbeat, dizziness or fainting while taking Klacid.
If you have to have any urine tests, tell your doctor you are taking Klacid as it
may affect the results of some laboratory tests.
If you are about to start taking a new medicine, tell your doctor or pharmacist that
you are taking Klacid.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking
Things you must not do
Do not use Klacid to treat any other complaints unless your doctor says so.
Do not give this medicine to anyone else, even if their symptoms seem similar to yours.
Things to be careful of
Be careful driving or operating machinery until you know how Klacid affects you.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking Klacid.
Klacid treats infections in most people, but it may have unwanted side effects in
All medicines can have side effects. Sometimes they are serious; most of the time
they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by this list of possible side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
While you are taking Klacid
Tell your doctor if you experience any of the following:
stomach cramps and pains
nausea, vomiting and severe diarrhoea
oral thrush or vaginal thrush
change in taste sensation
asthma, shortness of breath
Tell your doctor immediately if you notice any of the following as you may need urgent
yellowing of the eyes or skin (jaundice)
feeling generally unwell and having poor appetite
dizziness, confusion, hallucinations, convulsions
fainting, irregular heart beat
any type of skin rash, itching, hives
severe diarrhoea, especially if bloody
severe upper stomach pain, with nausea and vomiting (pancreatitis)
Stop taking Klacid and tell your doctor immediately or go to casualty at your nearest
hospital if any of the following happen:
swelling to the face, lips, mouth, throat or neck which may cause difficulty in swallowing
or breathing or sudden collapse
After you have finished taking Klacid
Tell your doctor immediately if you notice any of the following side effects, even
if they occur several weeks after stopping treatment with Klacid:
severe stomach or abdominal cramps
watery and severe diarrhoea, which may also be bloody
fever, in combination with one or both of the above
These are rare but serious side effects. You may have a serious condition affecting
your bowel and you may need urgent medical care.
Do not take any diarrhoea medicine without first checking with your doctor.
Other side effects not listed above may also occur in some patients. Ask your doctor
or pharmacist for more information about side effects, as they have a more complete
list of side effects. Inform your doctor promptly about these or any other symptoms.
If the condition persists or worsens, seek medical attention.
Do not be alarmed by this list of possible side effects. You may not experience any
of them or only some of them.
Tell your doctor if you notice anything that is making you feel unwell while you are
taking, or soon after you have finished taking Klacid, even if it is not on this list.
After using Klacid
Keep your medicine where children cannot reach them.
A locked cupboard at least 1.5 metres above the ground is a good place to store medicines.
Keep Klacid tablets in a cool dry place, protected from light, where the temperature
stays below 25°C.
Powder for Oral Liquid:
Klacid Powder for Oral Liquid should be kept in a cool dry place, protected from light,
where the temperature stays below 30°C.
The reconstituted suspension can be used for up to 14 days when stored below 30°C.
DO NOT REFRIGERATE.
Do not keep Klacid or any other medicine in the bathroom or near a sink. Do not leave
Klacid in the car or on window sills. Heat and dampness can destroy some medicines.
If your doctor tells you to stop taking Klacid, or your medicine has passed its expiry
date, ask your pharmacist what to do with any medicine that is left over.
What it looks like
Klacid 250mg tablets are yellow, oval, film-coated tablets. Each blister pack contains
Klacid 500mg tablets are pale yellow, oval, film-coated tablets.
Klacid Powder for Oral Liquid 250mg/5mL has a white to pale yellow colour with a fruit
punch aroma. The reconstituted suspension has a tendency towards grittiness.
The active ingredient in Klacid is clarithromycin.
Each Klacid 250 mg tablet contains 250mg of clarithromycin.
Each Klacid 500 mg tablet contains 500mg of clarithromycin.
The tablets also contain:
Colours are titanium dioxide and quinoline yellow
Klacid 250mg tablets also contain pregelatinised maize starch
Klacid tablets do not contain lactose or gluten.
Klacid Powder for Oral Liquid 250mg/5mL:
Each 5mL of Klacid Powder for Oral Liquid contains 250mg of clarithromycin (the active
It also contains:
fruit punch flavour
Klacid 250mg and 500mg tablets and Klacid Powder for Oral Liquid are supplied in Australia
Mylan Health Pty Ltd
Level 1, 30-34 Hickson Road
Millers Point, NSW 2000
Phone: 1800 314 527
Australian registration numbers:
Klacid 250mg Tablets: AUST R 79576 (bottle) & 79564 (blister)
Klacid 500mg Tablets: AUST R 50682 (bottle) & 52473 (blister)
Klacid Powder for Oral Liquid 250mg/5mL: AUST R 56729
Date of information:
30 August 2017