Autoimmune Disease Development Of Therapies

Treatment of autoimmune disorders involves three major approaches:-

  • therapies to improve signs and symptoms
  • therapies to modify the natural course and progression of disease
  • therapies directed at complications that arise from organ damage caused by the disease

Medications used to treat autoimmune diseases

Several groups of medications are used to treat autoimmune disorders. Some of these include:-

  • Those that relieve symptoms like pain and inflammation including non steroidal anti-inflammatory agents (NSAIDs) or pain killers.
  • Corticosteroids are used to suppress the immunity and prevent the exaggerated response.
  • Those agents useful for replacement for a deficient hormone or agent in the body. For example, thyroid hormone is provided as pills in autoimmune or Hashimoto thyroiditis and insulin is given as injections in Type 1 diabetics.
  • Immunosuppressant drugs are used to inhibit the activity of the immune system.
  • Anti-TNF medications are used to block the inflammation and are used in autoimmune arthritis and psoriasis.
  • Physical therapy is advocated to encourage and maintain optimum mobility.
  • Surgery may be opted to replace the damaged joint or to treat intestinal blockage in the case of Crohn's disease.

New approaches

There are several new approaches to the treatment of autoimmune disorders. The number of new approaches is on the rise due to ongoing stem cell research and genetic research.

More biological agents similar to existing anti-TNF agents, monoclonal antibodies, gene-based delivery systems, modulators of the immune system and cell-based treatments, tissue and organ engineering procedures are on their way to treating autoimmune diseases.

Therapies based on complementary and alternative medicine are also being explored for their efficacy and safety.

Stem cell transplantation

Stem cell transplantation is a new and promising strategy. It aims to reconstitute the immune system.

Several strategies that are antigen specific are also being developed that could help in disease like multiple sclerosis, rheumatoid arthritis, scleroderma, systemic lupus erythematosus, and psoriatic arthritis.


In addition to the development of new therapeutic targets, are studies to develop new biomarkers for the diseases. These biomarkers can help determine the stage, activity, and progression of disease and help to assess response to therapy.

These biomarkers would also enable physicians treating the diseases to choose from available therapies to provide the best suited treatment.



Further Reading

Last Updated: Jul 7, 2023

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Mandal, Ananya. (2023, July 07). Autoimmune Disease Development Of Therapies. News-Medical. Retrieved on July 19, 2024 from

  • MLA

    Mandal, Ananya. "Autoimmune Disease Development Of Therapies". News-Medical. 19 July 2024. <>.

  • Chicago

    Mandal, Ananya. "Autoimmune Disease Development Of Therapies". News-Medical. (accessed July 19, 2024).

  • Harvard

    Mandal, Ananya. 2023. Autoimmune Disease Development Of Therapies. News-Medical, viewed 19 July 2024,


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk