What is Vitamin E?

Vitamin E is a term that encompasses several subtypes of tocopherols, which are fat-soluble and exhibit antioxidant properties.  Therefore, vitamin E can inhibit free radicals in the body from reacting and causing damage to the genetic makeup of natural cells in the body.

It has been suggested that vitamin E may be linked to a number of potentially fatal diseases, such as heart disease and cancer, by offering a protective effect. The outcomes of research examining these effects vary; thus, the complete role of vitamin E in the body remains unclear.

Image Credit: Evan Lorne / Shutterstock.com

Risk of heart disease

Early studies suggesting a preventative effect of vitamin E supplements for heart disease held promising results, although follow-up studies failed to support this notion. As a result, the currently available scientific evidence is conflicting.

Some research has indicated a risk reduction of 20-40% for those patients who supplemented vitamin E for at least two years. However, other studies have not found a significant difference from the control group, with one study that associated vitamin E with a slightly increased risk of heart failure.

As a result, the supplementation of vitamin E is not justified for the prevention of heart disease at this point in time, although it may offer some benefit.

Risk of cancer

Theoretically, the antioxidant effect of vitamin E should help to minimize the effect of free radicals in the body, thus reducing the risk of cancer. However, when put to the test in scientific trials, this has not been shown to be the case.

Observational studies of vitamin E intake through supplementation or dietary sources have not found a protective effect against general or specific cancers. Some studies suggest that supplementation may lower risk of prostate cancer in male smokers; although, when a larger trial of 18,000 men tested this hypothesis, the study was halted due to early results showing an increased risk of cancer in those men taking vitamin E.

To date, no conclusive evidence has been able to enlighten the situation in regards to the effect of vitamin E. It is possible there is a preventative effect, although the data to demonstrate this is weak.

Ocular diseases

When vitamin E is taken in combination with vitamin C, beta-carotene, and zinc, a protective effect against age-related macular degeneration has been shown. However, when vitamin E is taken as a stand-alone supplement, this benefit is not evident, thereby suggesting that the other vitamins supplemented may be responsible for this effect.


There have been mixed results of studies determining the benefit of vitamin E, often in combination with vitamin C, in the prevention of Alzheimer’s disease and dementia.

Free radicals are believed to play a large role in the degeneration of cognitive function; therefore, from a theoretical perspective, a benefit is likely. Small improvements in cognitive function may be seen in those affected by the disease, as well as a preventative effect, although not all studies have demonstrated these benefits.

Parkinson’s disease

A higher dietary intake of vitamin E has been associated with a risk reduction of Parkinson’s disease. However, for those who are affected by the disease, supplementation does not appear to slow progression of the disease or ease symptoms.

As the link between vitamin E and Parkinson's disease is based on dietary sources and not supplementation, it is possible that the results may be due to other vitamins and minerals present in the food sources.

Food sources

Vitamin E is available in several natural food sources, some of which include:

  • Asparagus
  • Avocado
  • Egg
  • Leafy greens
  • Milk
  • Nuts
  • Seeds
  • Vegetable oils
  • Wheat germ

Additionally, supplementation of vitamin E is available if the individual is likely to benefit from a higher intake of the vitamin.


Further Reading

Last Updated: Apr 26, 2021

Yolanda Smith

Written by

Yolanda Smith

Yolanda graduated with a Bachelor of Pharmacy at the University of South Australia and has experience working in both Australia and Italy. She is passionate about how medicine, diet and lifestyle affect our health and enjoys helping people understand this. In her spare time she loves to explore the world and learn about new cultures and languages.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Smith, Yolanda. (2021, April 26). What is Vitamin E?. News-Medical. Retrieved on June 17, 2024 from https://www.news-medical.net/health/What-is-Vitamin-E.aspx.

  • MLA

    Smith, Yolanda. "What is Vitamin E?". News-Medical. 17 June 2024. <https://www.news-medical.net/health/What-is-Vitamin-E.aspx>.

  • Chicago

    Smith, Yolanda. "What is Vitamin E?". News-Medical. https://www.news-medical.net/health/What-is-Vitamin-E.aspx. (accessed June 17, 2024).

  • Harvard

    Smith, Yolanda. 2021. What is Vitamin E?. News-Medical, viewed 17 June 2024, https://www.news-medical.net/health/What-is-Vitamin-E.aspx.


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Concordia researchers link vaping additives to lung damage