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Anti-cancer Properties of Silver Nanoparticles

The small size of silver nanoparticles and ability to induce cell death through multiple mechanisms makes them fantastic candidates for anti-cancer therapies.

9 Oct 2018

Features of Anaplastic Cells

Anaplasia describes cells which are undifferentiated, or a poorly differentiated. This means that they lose characteristics associated with a certain tissue.

8 Oct 2018

Nanostar Applications in Biomedicine

Nanostars are currently being researched as diagnostic agents for human disease and therapeutic agents such as cancer therapies.

8 Oct 2018

What is Astro Microbiology?

Astro microbiology (also called exo microbiology) is the study of microorganisms in space, or under space conditions.

8 Oct 2018

What are Bacterial Nanowires?

Some bacteria utilize electrically conductive protrusions to transfer electrons for various purposes. These are known as bacterial nanowires.

5 Oct 2018

What is Circular RNA (CircRNA)?

This article describes the structure and function of circular RNA (circRNA), its biological function and role in research.

5 Oct 2018

Single Particle Tracking in Biology

Single-particle tracking (SPT) is used to define the diffusion dynamics of nanoparticles and biomolecules, through the use of fluorescent probes.

3 Oct 2018

Common Problems in Cell Culture

Contamination is a common problem in cell culture. Sources of contamination include mycoplasma, yeast, bacteria, and chemicals.

3 Oct 2018

DNA Labelling Using DAPI: Methodology

DAPI, or 4,6-diamidino2-phenylindole, is a fluorescent nucleic acid dye used to preferentially stain double-stranded DNA. It is commonly used in flow cytometry

1 Oct 2018

Carbon Nanodots for Protein Biology

Carbon nanodots are carbon nanoparticles which are less than 10 microns (µm) in size. They are used in drug delivery and protein studies.

1 Oct 2018

What are Nanostars?

Nanostars are a type of nanoparticle consisting of a spherical core and multiple branches, resembling a ‘star’.

1 Oct 2018

How to Read LC-MS Chromatograms

Liquid chromatography - mass spectrometry (LC-MS) combines two approaches to separate and identify molecules or compounds present in a sample. High performance liquid chromatography (HPLC) separates components of a mixture, whereas mass spectrometry (MS) offers the detection tools to identify them. LC-MS, as a method for understanding biological molecules, has applications in both research and clinical diagnosis.

19 Sep 2018

Hybrid Capture-Based Human Papillomavirus Detection Versus PCR

High-risk types of human papilloma virus (HPV) are one of the most important risk factor for cervical carcinomas in women. Conventionally, pap smear cytology and PCR have been used to screen for the presence of HPV. Recently, a new commercial HPV test has been proposed for diagnosis of HPV-Hybrid capture assay.

19 Sep 2018

Applications of Thin Layer Chromatography

Thin layer chromatography has wide field of applications that include pharmaceuticals, food, cosmetics and phytochemistry.

18 Sep 2018

Flash Column Chromatography Methodology

Flash column chromatography was developed in 1978 as an alternative method to long column chromatography.

18 Sep 2018

High Performance Liquid Chromatography (HPLC) Applications

High performance liquid chromatography, more commonly known by the acronym HPLC, is a method used to identify substances in a mixture. There are several types of HPLC, such as reversed-phase, denaturing, and immobilized enzyme reactor (IMER) HPLC.

18 Sep 2018

MicroRNA Profiling Methods and Applications

MicroRNAs (miRNAs) are small, short non-coding RNAs that bind to specific messenger RNAs (mRNAs) and regulate gene expression either by degradation or by translational inhibition of the mRNA.

18 Sep 2018

Tissue Nanotransfection Methodology

The application of nanotechnology to the field of medicine and healthcare offers the possibility to produce innovative nanoengineering techniques in the repair and regeneration of tissues and organs.

17 Sep 2018

Analyzing Mitohormesis

When ingested by humans, micro-doses of toxins result in a positive adaptive immune response in cells and organs, whereas higher-doses have detrimental effects. This biphasic response is known as hormesis and comes from the Greek word which translates as ‘to impel’.

17 Sep 2018

What is Methylation-Specific PCR?

DNA methylation is an important epigenetic process which has diverse roles to regulate gene expression, imprinted genes, inactivation of X chromosomes, and the dysregulation of these patterns in diseases.

17 Sep 2018