Life Science Articles

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Single Plane Illumination Microscopy (SPIM) in Cell Biology

Visualising cell behaviour has been the goal of many techniques developed in the 20th and 21st century. Cells were initially visualized after removing from the organism after death.

23 Aug 2018

Essential Amino Acids

Amino acids are the monomeric compounds that combine to form proteins. Essential amino acids cannot be made by the body, so must come from our diet.

23 Aug 2018

Single Cell RNA-Sequencing

Single cell RNA-sequencing measures the distribution levels of each gene across of population of cells. This can be used to study the development and physiology of cells, as well as disease.

22 Aug 2018

Opsonization is the mechanism by which targeting of particles for destruction through phagocytosis becomes enhanced. Opsonins are molecules that mark foreign particles for phagocytosis. Phagocytosis is the cellular process for removes pathogens and dead or dying cells.

22 Aug 2018

Wnt Signalling Pathway

Wnt signalling is an important, evolutionarily conserved signalling pathway that determines cell fate decisions and tissue patterning during embryonic development and later development.

20 Aug 2018

Photoactivated Localization Microscopy in Research

Photoactivated Localization Microscopy (PALM) is a form of super resolution fluorescence microscopy (SR) which enables highly resolved imaging to be produced through the selective targeting of fluorescent markers within a specimen.

20 Aug 2018

Importance of Particle Size Analysis in Industry

Particle size analysis gives information on the size distribution of particles. This can be used to calculate different properties of a particle and how they will act under certain conditions. This information is critical in industries to achieve different goals.

20 Aug 2018

Phosphoproteomics in Research

Phosphoproteomics is an important tool in the life sciences, allowing for the study of regulatory changes with variation in conditions and time.

20 Aug 2018

Nanoparticle Tracking Analysis

Nanoparticle tracking analysis (NTA) is a method for visualizing and analyzing particles in liquids. NTA suspends small particles (~10-1000 nm) in a liquid, this allows for the determination of a size distribution profile.

19 Aug 2018

Importance of Studying the Interactome

Interactome refers to all sets of molecular interactions inside a cell. Although an interactome usually used for protein-protein interactions, they may also refer to metabolic networks or gene regulatory networks.

16 Aug 2018

Stimulated Emission Depletion (STED) Microscopy in Research

Stimulated emission depletion (STED) microscopy relies on the controlled excitation of a series of emitters followed by their subsequent depletion for super-resolved imaging.

16 Aug 2018

Scattering-Assisted Localization Microscopy

Scattering-Assisted Localization Microscopy (SALM) is a super-resolution microscopy tool where high resolution is obtained based on the size of the grain in the speckle pattern on the sample.

16 Aug 2018

Real-Time/Quantitative PCR in Industry

Polymerase Chain Reaction (PCR) is a method which utilizes the mechanism of DNA replication to amplify a specific part of DNA. This involves the use of DNA polymerase, which makes new strands of DNA using free nucleotides.

15 Aug 2018

What is the Interactome?

An interactome network refers to all the protein-protein interactions which take place inside a cell. Such interactome maps have been created for yeast, worms, flies, and are beginning to be created for humans.

15 Aug 2018

Electrochemical Impedance Spectroscopy Applications

Electrochemical impedance spectroscopy (EIS) is an analysis method used for studies of surfaces, batteries, photovoltaic systems, and some life science applications.

14 Aug 2018

Surface Localized Antimicrobial Display Applications

With a rise in antibiotic resistance towards the existing range of antibiotics, there is a need to discover a new class of previously unknown antibiotic peptides.

14 Aug 2018

Microfluidic Enrichment in Single-Cell Analysis

In certain cancers, there can be cells which disseminate from the tumor into the blood. These are known as “circulating tumor cells”, and can metastasize to secondary sites.

14 Aug 2018

Karl Fischer versus Loss-On-Drying

Several methods are available to determine the water content of a substance, among which, loss-on-drying (LOD) and Karl Fischer titration are commonly used to determine the moisture content in pharmaceuticals.

14 Aug 2018

Single-Cell Chromatin Modification Profiling

Modifications of the chromatin are crucial for the regulation of nearly all DNA-templated biological processes. Single-cell chromatin modification profiling can be used to assess chromatin modifications, which can provide relationships between epigenetic changes and physiological changes.

13 Aug 2018

Particle Size Analysis Techniques

Particle size analysis is used to characterize the size distribution of particles in a sample. This analysis can also be used to measure the particle size of solid materials, suspensions, emulsions, and aerosols

13 Aug 2018