Life Science Articles

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What is the Interactome?

An interactome network refers to all the protein-protein interactions which take place inside a cell. Such interactome maps have been created for yeast, worms, flies, and are beginning to be created for humans.

15 Aug 2018

Electrochemical Impedance Spectroscopy Applications

Electrochemical impedance spectroscopy (EIS) is an analysis method used for studies of surfaces, batteries, photovoltaic systems, and some life science applications.

14 Aug 2018

Surface Localized Antimicrobial Display Applications

With a rise in antibiotic resistance towards the existing range of antibiotics, there is a need to discover a new class of previously unknown antibiotic peptides.

14 Aug 2018

Microfluidic Enrichment in Single-Cell Analysis

In certain cancers, there can be cells which disseminate from the tumor into the blood. These are known as “circulating tumor cells”, and can metastasize to secondary sites.

14 Aug 2018

Karl Fischer versus Loss-On-Drying

Several methods are available to determine the water content of a substance, among which, loss-on-drying (LOD) and Karl Fischer titration are commonly used to determine the moisture content in pharmaceuticals.

14 Aug 2018

Single-Cell Chromatin Modification Profiling

Modifications of the chromatin are crucial for the regulation of nearly all DNA-templated biological processes. Single-cell chromatin modification profiling can be used to assess chromatin modifications, which can provide relationships between epigenetic changes and physiological changes.

13 Aug 2018

Particle Size Analysis Techniques

Particle size analysis is used to characterize the size distribution of particles in a sample. This analysis can also be used to measure the particle size of solid materials, suspensions, emulsions, and aerosols

13 Aug 2018

Super-Resolution Fluorescence Microscopy

Super-resolution (SR) fluorescence microscopy encompasses a variety of techniques that can exceed the diffraction limit – the point at which molecular nanostructures can be distinguished from one another.

13 Aug 2018

What is an Enzyme Cofactor?

In living organisms, there are many chemical reactions taking place. These reactions have many different functions, including breaking down the food we eat and getting energy from the broken down food. To facilitate this, there are a group of proteins known as enzymes.

12 Aug 2018

What is Biocatalysis?

Biocatalysis is “the use of natural substances to speed up (catalyze) chemical reactions”. In most cases, a group of proteins called enzymes will be carrying out the catalysis, but a combination of enzymes as well as cells can be used.

12 Aug 2018

Applications of Adipo-Clear

Humans have three types of fat cells – white, beige and brown – that work in concert to maintain, store, and use energy.

6 Aug 2018

Moisture Analysis Techniques

Many industries, including the food, chemical, and pharmaceutical product industries, depend heavily on exact knowledge of the moisture content of their products as part of quality control. Such measurements need to be rapid and reproducible in order to allow for immediate correction of the workflow if any flaw appears in the final product.

6 Aug 2018

Cell-to-Cell Communication in Fungi

To communicate with its neighbors, animal cells use gap junctions which are symplasmic connections through which molecules can diffuse from one cell to another.

3 Aug 2018

Missing Self Hypothesis for Natural Killer Cells

Natural killer cells are an integral part of the human immune system, representing the front line of defence against tumor-forming cells and pathogens. These cells utilise several different methods to differentiate between abnormal cells and the host’s own cells, and are coordinated by biochemical signals derived from the activation of their own cell-surface receptors.

3 Aug 2018

Bioactive Microbial Metabolites

Bioactivity or biological activity of the metabolite may be in vitro, in vivo, or at the level of whole organism.

2 Aug 2018

Nucleic Acid Labeling Applications

Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids labeled with enzymes, radioactive phosphates, or fluorophores.

2 Aug 2018