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Study finds cell-free RNA can be used to predict preeclampsia

Preeclampsia is a serious pregnancy disorder, marked by high blood pressure and the presence of proteins in urine, affecting between 2% and 4% of pregnant women worldwide, leading to about 46,000 maternal deaths and about 500,000 fetal and newborn deaths each year.

20 Jul 2023

New mRNA-based malaria vaccine shows promise in preclinical trials

Trans-Tasman research collaborators from Te Herenga Waka - Victoria University of Wellington's Ferrier Research Institute and the Malaghan Institute of Medical Research in New Zealand, and the Peter Doherty Institute for Infection and Immunity in Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasite Plasmodium in preclinical models.

20 Jul 2023

Research illuminates the genetic basis of human skeletal proportions

Combining data from full-body x-ray images and associated genomic data from more than 30,000 UK Biobank participants, researchers have helped illuminate the genetic basis of human skeletal proportions.

20 Jul 2023

Cells communicate in waves to coordinate movement

Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move.

20 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve.

20 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

New cellular atlas of the kidney sheds light on disease

Research is shedding light on kidneys, their critical functions, and predictors of disease.

19 Jul 2023

Study explores how ultraviolet radiation can alter the microstructure of human skin

Received wisdom says that staying out in the sun too long can make your skin tougher over time. Think about the "leathery" complexions of farmers, road crews and others who work long hours outdoors, or someone who spends too much time in tanning booths, or too much time on the beach during the summer.

19 Jul 2023

New refget version improves reliability of genomic data analysis

A widely-used tool that finds the exact references needed to pinpoint differences in our DNA just got a refresh.

19 Jul 2023

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva, have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial DNA and RNA in a single-celled, disease-causing parasite called Trypanosoma brucei.

19 Jul 2023

Neuroscientists discover new brain cells that help correct navigational errors

During routine navigation in daily life, our brains use spatial mapping and memory to guide us from point A to point B. Just as routine: making a mistake in navigation that requires a course correction.

19 Jul 2023

New kidney tissue atlas could advance understanding of kidney injury and disease

Researchers at Washington University School of Medicine in St. Louis helped lead a major study, funded by the National Institutes of Health (NIH), that uncovered rich cellular and molecular diversity in healthy and diseased kidneys, creating a kidney tissue atlas that will help further understanding of kidney injury and disease.

19 Jul 2023

Study provides new insights into the mechanism of Dmc1 filament assembly

Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction.

19 Jul 2023

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

The discovery of antibiotics in 1928 was a major turning point in the history of medicine. For the first time since the dawn of human civilization, doctors had gained access to an extremely powerful and effective tool to fight against a wide variety of bacterial infections.

19 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

AI-based analysis method accelerates study of cell structures

BESSY II's high-brilliance X-rays can be used to produce microscopic images with spatial resolution down to a few tens of nanometers.

18 Jul 2023

Tight junctions between cells may play a critical role in gastrulation in human embryos

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo.

18 Jul 2023

Gene Therapy Contract Development and Manufacturing: Challenges and Future Perspectives

In this interview conducted at the Cell and Gene Therapy Summit Tour London, we speak to Ramin Baghirzade, Global Head of Commercial at Charles River for Gene Therapy, about the Gene Therapy CDMO solutions that Charles River Laboratories offers and more.

From Charles Rivers Laboratories Cell and Gene Therapy 18 Jul 2023

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Study evaluated genes with copy number alterations to identify biomarkers for ovarian cancer prognosis.

18 Jul 2023

Life Science News

Study finds cell-free RNA can be used to predict preeclampsia

New mRNA-based malaria vaccine shows promise in preclinical trials

Research illuminates the genetic basis of human skeletal proportions

Cells communicate in waves to coordinate movement

Researchers discover new way to target bacterial cell wall

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

Using single-cell mass spectrometry to study antimicrobial treatment failure

New cellular atlas of the kidney sheds light on disease

Study explores how ultraviolet radiation can alter the microstructure of human skin

New refget version improves reliability of genomic data analysis

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

Neuroscientists discover new brain cells that help correct navigational errors

New kidney tissue atlas could advance understanding of kidney injury and disease

Study provides new insights into the mechanism of Dmc1 filament assembly

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

Eternal youth? Chemical cocktails prove effective in cell age reversal

AI-based analysis method accelerates study of cell structures

Tight junctions between cells may play a critical role in gastrulation in human embryos

Gene Therapy Contract Development and Manufacturing: Challenges and Future Perspectives

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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