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Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

Pheochromocytoma is a rare tumor, with an incidence of three to eight cases per million population per year.

28 Feb 2023

New funding to accelerate development of potential anti-cancer compound into the clinic

For the past few decades, Dr. Iwao Ojima has been working in his Stony Brook University Department of Chemistry Laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) to develop next-generation anti-cancer agents.

28 Feb 2023

Gut-on-a-chip devices can bridge lab models and human biology

The gut is one of the most complex organs in the body. Inside, it teems with a diverse microbial population that interacts and cooperates with intestinal cells to digest food and drugs.

28 Feb 2023

New purification approach could help make protein drugs more affordable and accessible

One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it.

28 Feb 2023

Extended parental provisioning may have played a key role in evolution of larger brains

A review of evidence from prior research provides new support for the possibility that the evolution of larger brains in some species was enabled through increased energy investment by parents in their offspring.

28 Feb 2023

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.

28 Feb 2023

First small molecules designed to stimulate immune cells against neuroblastoma

An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer.

28 Feb 2023

St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance.

28 Feb 2023

Scientists working to create revolutionary biocomputers powered by brain organoids

Artificial intelligence (AI) has long been inspired by the human brain. This approach proved highly successful: AI boasts impressive achievements – from diagnosing medical conditions to composing poetry.

28 Feb 2023

Mutation in a single non-coding gene found to be the source of multisystemic smooth muscle dysfunction syndrome

A team of investigators from Massachusetts General Hospital, a founding member of Mass General Brigham and Mass General for Children has identified - for the first time - the mutation in a single non-coding gene of a young patient responsible for the extremely rare disease known as multisystemic smooth muscle dysfunction syndrome, which causes profound cerebrovascular, gastrointestinal and urologic impairment.

28 Feb 2023

Life Science News

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Key 'traffic light' mechanism controlling genetic activity within cells revealed

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

New funding to accelerate development of potential anti-cancer compound into the clinic

Gut-on-a-chip devices can bridge lab models and human biology

New purification approach could help make protein drugs more affordable and accessible

Extended parental provisioning may have played a key role in evolution of larger brains

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

First small molecules designed to stimulate immune cells against neuroblastoma

St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists working to create revolutionary biocomputers powered by brain organoids

Mutation in a single non-coding gene found to be the source of multisystemic smooth muscle dysfunction syndrome

Study finds unique epigenetic biosignature in individuals with post-COVID syndrome

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Study reveals new mechanism in the arms race between bacteria and viruses

Using the origami technique to design RNA nanostructures

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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