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Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Metatranscriptomics analysis reveals the existence of over ten thousand viroids and viroid-like RNAs.

1 Feb 2023

Commonly prescribed antidepressants can increase bacteria's resistance to antibiotics

University of Queensland researchers have found a range of commonly prescribed antidepressants can increase bacteria's resistance to antibiotic medications.

1 Feb 2023

Cochlear avatars provide a platform for deciphering the mechanisms of sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

New discovery about "killer torpedoes" may be the next breakthrough in cancer treatment

In our body, we have both an innate immune system and an immune system that is developed throughout life. Part of the innate immune system consists of so-called NK cells.

31 Jan 2023

New technique offers a two-prong approach to attacking cancers

When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall "cloak," the treatment exposes cancer cell markers that had previously been hidden from the body's defenses, researchers at the University of Michigan have shown.

31 Jan 2023

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers determine whether protein expression in nasal fluid samples could assist in the diagnosis of severe asthma subtypes.

31 Jan 2023

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

A research team, led by Professor Sung Ho Park in the Department of Biological Sciences at UNIST announced the results of a study on osteoblasts that damage joint bones in patients with rheumatoid arthritis.

31 Jan 2023

Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

Cornell research provides new insight into chemotherapy agent's effect on DNA

New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.

30 Jan 2023

Structure and function of the first FDA-approved treatment for Ebola virus discovered

Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus).

30 Jan 2023

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

30 Jan 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

Study focuses on plasticity of the synapses between the hypothalamus and hippocampus

The complexity of the human brain is unparalleled. Fortunately, thanks to constant progress in neuroscience over the past decades, we have started to make some sense of the human brain.

30 Jan 2023

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

Medications like dextromethorphan, used to treat coughs caused by cold and flu, could potentially be repurposed to help people quit smoking cigarettes, according to a study by Penn State College of Medicine and University of Minnesota researchers.

30 Jan 2023

$1 million grant will help University of Utah chemists to speed up the drug development process

Michael Grünwald, Ryan Looper and Rodrigo Noriega, of the University of Utah Department of Chemistry, received a $1 million grant from the W.M. Keck Foundation funding studies of currently unpredictable aspects of the process of crystallization.

30 Jan 2023

Novel class of sulfonamides to block malaria transmission

Malaria is a devastating disease, with 247 million cases and 619,000 deaths reported in 2021 alone. Malaria causes fever and a flu-like illness that occurs when people are infected with the parasite Plasmodium falciparum, which is spread by mosquitoes.

30 Jan 2023

Novel mathematical model simulates how an average person's body regulates potassium

Having levels of potassium that are too high or too low can be fatal. A new mathematical model sheds light on the often mysterious ways the body regulates this important electrolyte.

30 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

The vital role of oxytocin - the "love hormone" - for social attachments is being called into question. More than forty years of pharmacological and behavioral research has pointed to oxytocin receptor signaling as an essential pathway for the development of social behaviors in prairie voles, humans, and other species, but a genetic study publishing in the journal Neuron on January 27 shows that voles can form enduring attachments with mates and provide parental care without oxytocin receptor signaling.

29 Jan 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

Life Science News

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Commonly prescribed antidepressants can increase bacteria's resistance to antibiotics

Cochlear avatars provide a platform for deciphering the mechanisms of sensorineural hearing loss

New discovery about "killer torpedoes" may be the next breakthrough in cancer treatment

New technique offers a two-prong approach to attacking cancers

A machine-learning approach to identify asthma subtypes based on molecular signatures

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

Actin influences cancer metastases in many ways

Cornell research provides new insight into chemotherapy agent's effect on DNA

Structure and function of the first FDA-approved treatment for Ebola virus discovered

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

New candidate molecule could become an effective non-hormonal male contraceptive

Study focuses on plasticity of the synapses between the hypothalamus and hippocampus

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

$1 million grant will help University of Utah chemists to speed up the drug development process

Novel class of sulfonamides to block malaria transmission

Novel mathematical model simulates how an average person's body regulates potassium

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Latest Life Science News