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Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens.

11 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

First patient-derived stem cell model developed for studying oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

11 Jan 2022

Study reveals genomic regions that could help understand obesity

A new study has helped to shine light on the genetic pathways underlying obesity. The findings could help develop more personalized ways to help people maintain a healthy weight.

11 Jan 2022

Modular super-enhancer regulates gene expression involved in retina development

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell identity.

11 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

A team of researchers recently analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 patients.

11 Jan 2022

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Researchers at Université de Montréal have created a nanoantenna to monitor the motions of proteins. Reported this week in Nature Methods, the device is a new method to monitor the structural change of proteins over time – and may go a long way to helping scientists better understand natural and human-designed nanotechnologies.

10 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

Hybrid incompatibilities can be dependent on the environment, fish study suggests

You're likely familiar with the idea of the sterile mule: a hybrid animal born of a horse and a donkey that is unable to breed.

10 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Locust study reveals a ‘surprisingly simple’ approach to recognize an odor

Smell a cup of coffee. Smell it inside or outside; summer or winter; in a coffee shop with a scone; in a pizza parlor with pepperoni -; even at a pizza parlor with a scone! -; coffee smells like coffee.

10 Jan 2022

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

Researchers conducted a computational analysis of the furin cleavage domain (FCD) of SARS-CoV-2 and its variants, as well as several other viruses.

10 Jan 2022

Researchers develop new biopsy technology for profiling multiple tumor microenvironment biomarkers

A team led by University of California, Irvine researchers has developed a new biopsy technology that can profile multiple tumor microenvironment biomarkers simultaneously, revealing cellular spatial organization and interactions that will help advance personalized disease diagnosis and treatment.

10 Jan 2022

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of lipids to the signaling dynamics of RAS, a family of proteins whose mutations are linked to numerous cancers.

10 Jan 2022

Researchers identify gene expression signatures linked to suicide risk

Is risk of suicide in our genes? Findings of an international scientific team led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that gene expression studies could offer insights into the underlying causes of suicide, a highly complex public health problem that takes the lives of more than 800,000 people each year worldwide.

10 Jan 2022

Life Science News

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

First patient-derived stem cell model developed for studying oculocutaneous albinism

Study reveals genomic regions that could help understand obesity

Modular super-enhancer regulates gene expression involved in retina development

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Hybrid incompatibilities can be dependent on the environment, fish study suggests

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Locust study reveals a ‘surprisingly simple’ approach to recognize an odor

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

Researchers develop new biopsy technology for profiling multiple tumor microenvironment biomarkers

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

Researchers identify gene expression signatures linked to suicide risk

Scientists unravel how blood cells mount the first line of defense against viruses

Mice study shows how an antimicrobial found in toothpaste can trigger gut inflammation

Rising temperatures lead to increased prevalence of Vibrio bacteria in UK waters

Therapeutic in vivo synthetic chemistry used to make anticancer drugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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