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Novel vectors reduce the risks associated with ocular gene therapies

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.

22 Feb 2021

Study illuminates the role of HAND2 gene in timing of human labor

A new study illuminates how a gene called HAND2 may have a hand in the timing of human labor.

22 Feb 2021

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Long-term sleep deprivation is detrimental to health, increasing the risk of psychiatric and somatic disorders, such as depression and cardiovascular diseases.

22 Feb 2021

Human monoclonal antibodies can act as a substitute for traditional antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The

22 Feb 2021

Cancer cell vulnerability could be a potential target for interrupting tumor growth

Unraveling the unique characteristics of cancer cells and finding less-harmful ways to stop their growth have long been a focus for cancer researchers worldwide.

22 Feb 2021

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.

22 Feb 2021

Researchers study how the methylation of proteins affects different mitochondrial processes

Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to aging.

20 Feb 2021

Researchers use functional test to measure the effect of inherited variants in BRCA2 cancer gene

Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS).

20 Feb 2021

Scientists describe genetic mechanisms behind mating process of ciliates

Conjugation (or mating) of ciliates is a unique phenomenon among living beings. They have sex not for reproduction or pleasure — they seek to increase genetic variation.

20 Feb 2021

Study provides new information about the structure of prion proteins

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

20 Feb 2021

Direct cloning method aims to accelerate large-scale discovery of novel natural products

Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications.

20 Feb 2021

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

20 Feb 2021

Study: Longevity gene protects brain stem cells from the harmful effects of stress

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

20 Feb 2021

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells -- like drops of oil in water.

20 Feb 2021

Meta-study provides an overall picture of the neural basis of sign language

The ability to speak is one of the essential characteristics that distinguishes humans from other animals. Many people would probably intuitively equate speech and language.

20 Feb 2021

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Creating "super soldiers" of specific white blood cells to boost an anti-tumour response has been shown in a series of elegant experiments by Princess Margaret researchers.

20 Feb 2021

Researchers find new way to enhance the sensitivity of electrochemical micro-sensors

A team led by researchers at the New York University Tandon School of Engineering have found a new way of enhancing the performance of electrochemical micro-sensors.

20 Feb 2021

Researchers seek to develop new cell culture technique to replace animal testing

While many studies take place in a petri glass in toxicology research, for some processes there is still a need for animal components such as serum or liver cell tissue.

20 Feb 2021

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Researchers at the Institut de Neurociències obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis

19 Feb 2021

Uninherited genetic mutations can cause spina bifida

Genetic mutations which occur naturally during the earliest stages of an embryo's development can cause the severe birth defect spina bifida, finds a new experimental study in mice led by UCL scientists.

19 Feb 2021

Life Science News

Novel vectors reduce the risks associated with ocular gene therapies

Study illuminates the role of HAND2 gene in timing of human labor

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Human monoclonal antibodies can act as a substitute for traditional antibiotics

Cancer cell vulnerability could be a potential target for interrupting tumor growth

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Researchers study how the methylation of proteins affects different mitochondrial processes

Researchers use functional test to measure the effect of inherited variants in BRCA2 cancer gene

Scientists describe genetic mechanisms behind mating process of ciliates

Study provides new information about the structure of prion proteins

Direct cloning method aims to accelerate large-scale discovery of novel natural products

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

Study: Longevity gene protects brain stem cells from the harmful effects of stress

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Meta-study provides an overall picture of the neural basis of sign language

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Researchers find new way to enhance the sensitivity of electrochemical micro-sensors

Researchers seek to develop new cell culture technique to replace animal testing

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Uninherited genetic mutations can cause spina bifida

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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