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Researchers decipher deadly bacterial infection in pigs

The Clostridium perfringens bacterium is part of the large Clostridium genus which can cause various fatal illnesses in animals and humans.

4 Jun 2020

Human protein plays key role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome

4 Jun 2020

Small protein has a large impact on bacterial gene regulation

Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding protein ProQ is involved in the activation of more than 250 bacterial genes.

4 Jun 2020

Immune responsive nanoparticles for COVID-19 vaccine delivery

Analytik reports how the renowned Quadram Institute has invested in a ZetaView Nanoparticle Tracking Analyser to help them develop a new approach for vaccine delivery based on engineering the natural ability of resident gut bacteria to generate nanoparticle sized Outer Membrane Vesicles.

From Analytik Ltd 4 Jun 2020

Protein markers could help predict how ill a COVID-19 patient will become

Researchers at the Francis Crick Institute and Charité – Universitätsmedizin Berlin have identified 27 protein biomarkers that could be used to predict whether a patient with COVID-19 is likely to become severely ill with the disease.

4 Jun 2020

Diet and gut microbiome affect outcomes of chemotherapy

What we eat can affect the outcome of chemotherapy – and likely many other medical treatments – because of ripple effects that begin in our gut, new research from the University of Virginia suggests.

4 Jun 2020

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Hesperos Inc., pioneers of the Human-on-a-Chip in vitro system, today announced the publication of a new peer-reviewed publication that describes how the company’s technology can be used to investigate immune responses following treatment with biological therapeutics for multi-organ systemic diseases, including cancer, infectious diseases and inflammatory disorders.

4 Jun 2020

Beckman Coulter Life Sciences’ RNAdvance Viral XP kit listed for use in EUA-authorized COVID-19 testing

Beckman Coulter Life Sciences today announced RNAdvance Viral XP has been added to the list of acceptable extraction methods for use in the Centers for Disease Control’s EUA-authorized COVID-19 test referenced in the FDA’s FAQ on testing for SARS-CoV-2. Laboratories are now permitted to independently validate RNAdvance Viral XP for use.

From Beckman Coulter Life Sciences 4 Jun 2020

Base Genomics launches and raises $11 million USD to progress development of its TAPS technology

Epigenetics company Base Genomics has launched with a team of leading scientists and clinicians to set a new gold standard in DNA methylation detection.

4 Jun 2020

Using advanced microscopy techniques to see single molecules of telomerase in living cells

Canadian scientists have achieved a first in the study of telomerase, an essential enzyme implicated in aging and cancer.

3 Jun 2020

Scientists uncover why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

3 Jun 2020

Study sheds new light on how respiratory virus breaks into cells to cause infection

New research from University of Alberta microbiologists has shed new light on how the respiratory syncytial virus (RSV)--one of the most common viral infections--breaks into our cells to cause infection.

3 Jun 2020

Artificial red blood cells mimic the favorable properties of natural ones

Scientists have tried to develop synthetic red blood cells that mimic the favorable properties of natural ones, such as flexibility, oxygen transport and long circulation times.

3 Jun 2020

‘Terminator’ protein suppresses tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

3 Jun 2020

Despite landscape obstacles, pronghorn exhibit little genetic variation

A University of Wyoming researcher led a study that showed Wyoming pronghorn exhibit little-to-no population genetic differentiation even though their range spans hundreds of kilometers, multiple mountain ranges, and three major interstate highways.

3 Jun 2020

Bacteria that live in soil and on people have extensive antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

Study maps genes essential for metabolic function of two common bacteria

A study in Cell Reports maps genes essential for the metabolic function of M. agalactiae and M. pneumoniae, two common bacteria that infect livestock and humans respectively.

2 Jun 2020

Bacteria lurking in cancer cells may affect treatment

Cancer cells are comfy havens for bacteria. That conclusion arises from a rigorous study of over 1,000 tumor samples of different human cancers.

2 Jun 2020

New advance addresses a big challenge with using CRISPR in cancer patients

A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to a new study from ChristianaCare's Gene Editing Institute in the journal Molecular Cancer Research.

2 Jun 2020

Human waste could be used to create nitrogen-rich fertilizer

Researchers from Cornell University's College of Agriculture and Life Sciences and the Canadian Light Source at the University of Saskatchewan have proven it is possible to create nitrogen-rich fertilizer by combining the solid and liquid components of human waste.

2 Jun 2020