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Researchers create random versions of human genomes to study disease

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

31 Jan 2025

Breakthrough model simulates human bone marrow function in the lab

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

31 Jan 2025

INTEGRA Biosciences' reagent dispenser now supports SiLA-2 integration

INTEGRA Biosciences’ WELLJET reagent dispenser now supports API commands based on the SiLA-2 standardized communication protocol for lab automation. This new functionality will make it even easier to integrate the WELLJET into automated laboratory workflows, helping labs to enhance their productivity and reproducibility.

30 Jan 2025

New light-controlled tools offer real-time protein control in living cells

A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells.

30 Jan 2025

Study identifies six genetic regions associated with anterior uveitis

An international study led by the University of Oulu and Oulu University Hospital has identified six genetic regions associated with the inflammation of the eye's iris, also known as anterior uveitis.

30 Jan 2025

New research shines light on position-specific hallmarks of cancer

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol Research Institute shows, for the first time, that within a tumor, the expression of the different hallmarks of cancer is not cell-specific, but rather position-specific.

30 Jan 2025

Study reveals how glial cells respond to damage in neuron dendrites

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and protect neurons from harm.

29 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

High-speed in-line force mapping unveils E. coli cell division dynamics

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples must be meticulously prepared, killing any live specimens.

29 Jan 2025

Genetic predisposition plays a role in how coffee tastes bitter to some more than others

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

29 Jan 2025

New approach unveiled to accurately predict and engineer protein metalation

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life.

29 Jan 2025

Study identifies potential gain of function mutation in retinoblastoma

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation."

29 Jan 2025

Exploring the interaction between cell death and cellular senescence in cancer

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

29 Jan 2025

DNA profiling could identify key players in illegal drug trade

DNA profiling technologies are rapidly advancing, creating the potential to identify individuals involved in making, packing and transporting illegal capsules by analyzing the exterior of the illicit drugs and the ziplock plastic bag in which they are carried.

29 Jan 2025

Bruker launches infrared imaging microscope for pharma and life science research

Bruker Corporation announced the launch of the LUMOS™ II ILIM , a quantum cascade laser (QCL) based infrared imaging microscope. The new LUMOS II ILIM redefines performance standards, enabling pharma and life science researchers to capture ultrafast IR images of expansive areas with enhanced spatial resolution.

From Bruker Optics 29 Jan 2025

Genetic fingerprint could help predict antibiotic resistance in bacteria

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization estimates it could surpass cancer and heart disease as the leading cause of death as more bacteria develop defenses to the drugs designed to combat them.

29 Jan 2025

Bio-Rad launches TrailBlazer Tag and TrailBlazer StarBright Dye Label Kits for antibody conjugation to StarBright Dyes

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today announced the launch of its TrailBlazer™ Tag and TrailBlazer StarBright™ Dye Label Kits.

29 Jan 2025

Schrödinger selects Sapio Sciences to enhance in silico drug discovery from plasmid to structure

Sapio Sciences, the science-aware™ lab informatics platform, today announced that Schrödinger, a global leader in computational chemistry, has adopted the Sapio Platform to improve data management, enhance lab efficiency, and accelerate the discovery of novel molecules.

From Sapio Sciences 29 Jan 2025

Trilobio introduces whole-laboratory automation platform at SLAS2025

Trilobio, developer of whole lab automation solutions for advancing biology research, today introduced the first version of its comprehensive robotics, lab equipment and software platform at the Society for Laboratory Automation and Screening conference, SLAS2025, alongside pilot customer data, demonstrating the platform's abilities in advancing research workflows.

From Trilobio 28 Jan 2025

AI technology uncovers genetic factors and treatment options for Parkinson's

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

28 Jan 2025