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RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

The Mass General Brigham Gene and Cell Therapy Institute (GCTI) today announced it has launched the RNA Therapeutics Core, a first-of-its-kind, state-of-the-art facility and resource to advance the use of RNA technologies within and beyond the Mass General Brigham research ecosystem.

3 Sep 2024

NSF AIRFoundry to advance RNA technology and nanoparticle design

In a typical foundry, raw materials like steel and copper are melted down and poured into molds to assume new shapes and functions.

3 Sep 2024

Study shows beta cells can function independently for glycemic control

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, and diabetes develops.

3 Sep 2024

Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

Researchers developed a global catalog of nearly one billion small open reading frames (smORFs) from microbial genomes, revealing significant protein diversity, particularly in archaea, and providing new tools for microbiome research.

2 Sep 2024

MYO1D mutation identified as a key factor in sperm defects and congenital conditions

The research uncovers a novel variant in the MYO1D gene that is linked to laterality defects, congenital heart diseases, and sperm defects in humans.

2 Sep 2024

Extraordinary cell division mechanism discovered in common dental plaque bacteria

One of the most diverse ecosystems on the planet is closer than you think - right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms.

2 Sep 2024

Alternative splicing may influence gene expression more than protein diversity

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA).

2 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

New method revolutionizes DNA-encoded chemical libraries

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.

2 Sep 2024

Scientists map food microbes and their gut microbiome impact

Researchers unveiled the curatedFoodMetagenomicData (cFMD) resource, revealing extensive microbial diversity in food and its impact on the human microbiome, with significant overlap found in infants.

1 Sep 2024

New method accelerates drug discovery from years to months

Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery.

30 Aug 2024

High temperatures affect bumblebee sense of smell and pollination efficiency

Climate change is affecting ecosystems in many different ways. One of its consequences are increasingly longer and more intense periods of heat, which affect essential natural processes – such as pollination. A team of researchers from Julius-Maximilians-Universität Würzburg (JMU) has now investigated in more detail how heat affects one particular player in these processes: The bumblebee.

30 Aug 2024

Innovative nickel tool enhances organic chemical reactions for drug creation

The invention of a tool capable of unlocking previously impossible organic chemical reactions has opened new pathways in the pharmaceutical industry to create effective drugs more quickly.

30 Aug 2024

Mosquito males’ visual and auditory cues reveal new insights for malaria control

A high-pitched buzzing sound in your ear is an unmistakable sign that a female mosquito is out on the hunt - for they, not males, drink blood. Hearing that tone might make you turn to try to swat the pest. But for a male mosquito, that tone means it's time to mate.

30 Aug 2024

Life Science News

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

NSF AIRFoundry to advance RNA technology and nanoparticle design

Study shows beta cells can function independently for glycemic control

Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

MYO1D mutation identified as a key factor in sperm defects and congenital conditions

Extraordinary cell division mechanism discovered in common dental plaque bacteria

Alternative splicing may influence gene expression more than protein diversity

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

New method revolutionizes DNA-encoded chemical libraries

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

Scientists map food microbes and their gut microbiome impact

New method accelerates drug discovery from years to months

High temperatures affect bumblebee sense of smell and pollination efficiency

Innovative nickel tool enhances organic chemical reactions for drug creation

Mosquito males’ visual and auditory cues reveal new insights for malaria control

Rare genetic mutation tied to increased risk of tuberculosis

EU-funded MASTER project develops first comprehensive database of food metagenomes

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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