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Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

New DNA test identifies men at highest risk of prostate cancer

A major new study of more than 140,000 men has identified 63 new genetic variations in the DNA code that increase the risk of prostate cancer.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Genetic mutation shown to cause bipolar disorder

Researchers have discovered a mutation that may increase the risk of bipolar disorder through a complex interplay between serotonin and mitochondrial signaling.

11 Jun 2018

Researchers identify new form of depression

In a new study, researchers from Hiroshima University have identified a new form of depression that could be used to inform a new generation of treatments.

11 Jun 2018

Research drug may one day be novel treatment for systemic inflammatory response syndrome

When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection.

11 Jun 2018

Researchers identify enzyme that controls cell’s collagen secretion

Researchers at Tokyo Institute of Technology have identified an enzyme that controls how much our cells secrete collagen.

11 Jun 2018

Study: Small RNA chains could regulate the genes involved in salmonella's virulence

A series of small RNA fragments are the regulator factors involved in a new control mechanism for salmonella virulence, a pathogenic bacterium which causes bacterial gastroenteritis with a high incidence -more than 100,000 cases per year- in Europe

8 Jun 2018

Researchers identify oldest bubonic plague genome

An international team of researchers led by the Max Planck Institute for the Science of Human History has analyzed two 3,800-year-old Y. pestis genomes that suggest a Bronze Age origin for bubonic plague.

8 Jun 2018

Using Nanomechanical Testing to Understand the Mechanical Efficiency of Biomaterials

Biological materials exhibit superior mechanical properties relative to their weight when compared to the majority of all man-made materials. In addition to this, organisms can construct these materials using a very limited palette.

From Bruker Nano Surfaces and Metrology 8 Jun 2018

International research team develops simplified CRISPR

Details of an advanced form of CRISPR technology have been published in Nature Communications.

8 Jun 2018

Scientists find role of schizophrenia gene in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

8 Jun 2018

International experts agree on need for human-relevant research to improve drug discovery

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

8 Jun 2018

Study reveals new genetic causes of non-syndromic cleft lip and palate

A study conducted by an international research team, which included investigators from Seattle Children's Research Institute, implicates variants in four genes as a primary cause of non-syndromic cleft lip and palate in humans.

8 Jun 2018

Researchers discover protein responsible for X chromosome inactivation

Researchers have discovered that the structural protein SMCHD1 is required to prevent genes from both X chromosomes being expressed in female mammals.

7 Jun 2018

Study reveals mechanism behind eye loss in blind cavefish

Blind cavefish lose critical eye tissues within a few days after their eyes begin to develop.

7 Jun 2018

Researchers find identity of stem-cell niche of the colon

Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible for its continuous renewal.

7 Jun 2018

Ralph N. Adams Award in Bioanalytical Chemistry to be presented at Pittcon 2019

The Ralph N. Adams Award in Bioanalytical Chemistry will be presented at Pittcon 2019, and includes a cash award and travel expenses.

From Pittcon 7 Jun 2018

Fluence Analytics announces distribution agreement with Nihon Rufuto in Japan

Fluence Analytics, a manufacturer of industrial and laboratory analytics products, today announced it has signed a distribution agreement with Nihon Rufuto, a Japanese company specializing in the import and domestic sales of scientific instruments.

From Yokogawa Fluence Analytics 7 Jun 2018