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Researchers uncover mechanism critical to keeping blood stem cells functional

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function - and defective regulation of protein production is common in certain types of aggressive human blood cancers.

6 Apr 2018

New research could pave way for better influenza vaccines

Influenza vaccines that better target the influenza surface protein called neuraminidase (NA) could offer broad protection against various influenza virus strains and lessen the severity of illness, according to new research published in Cell.

6 Apr 2018

Research reveals how bacteria prepare sticky adhesion protein

Researchers at Harvard Medical School, the University of California, San Francisco, and the University of Georgia have described how the protein that allows strep and staph bacteria to stick to human cells is prepared and packaged.

6 Apr 2018

Largest genomic analysis supports additional classification of tumors

University of North Carolina Lineberger Comprehensive Cancer Center researchers are reporting the concluding findings from a major analysis of nearly 10,000 different tumor samples that focused on identifying similarities between cancers based on changes in their genes, and the way their genes are expressed.

6 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

Scientists identify key genetic events responsible for initiating childhood leukemia

The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of new targeted drugs.

6 Apr 2018

Agilent and BioTek announce new integrated metabolic analysis and imaging solution

Agilent Technologies Inc. and BioTek Instruments, Inc., today announced a new, integrated solution that combines cellular metabolic analysis and imaging technologies.

From Agilent Technologies 6 Apr 2018

DrySyn OCTO parallel synthesizer helps improve workflow in early stage discovery chemistry

Asynt reports on how a DrySyn OCTO 8-position parallel synthesizer has benefited early stage discovery chemistry at Cancer Research UK.

From Asynt 6 Apr 2018

Waking up “sleeping” stem cells in the brain could improve its ability to repair injury

Researchers have identified a new type of stem cell that could boost the brain’s ability to repair damage caused by brain injury or disease.

6 Apr 2018

Scientists create organoids that could help guide bladder cancer treatment

Researchers have created patient-specific bladder cancer organoids that imitate many of the features of real tumors and may therefore be used to study how cancer evolves.

6 Apr 2018

Study provides systematic view of gene enhancer activity in diverse tumors

At the heart of any cancer diagnosis or treatment are cells. If one thinks of the cell components controlling gene activation as a Russian nesting-doll of gene regulatory layers, within those increasingly smaller tiers are short pieces of non-coding DNA called enhancers.

5 Apr 2018

New method simplifies genetic modification of T-cells in mice

A new method enables genes in living T-cells in mice to be modified quickly and efficiently. It makes use of plasmids, a tried-and-tested method of genetic engineering.

5 Apr 2018

Research links DNA variants to increased risk of IBS in women

New research coordinated by Karolinska Institutet in Sweden links certain DNA variants to increased risk of irritable bowel syndrome in women. The findings, published in the scientific journal Gastroenterology, might help explain why IBS is more common in women than in men.

5 Apr 2018