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Researchers identify novel gene involved in familial breast cancer

An international research consortium led by Dr Jordi Surrallés, director of the Genetics Service at the Hospital de Sant Pau and professor of Genetics at the UAB, and by Dr Miquel Àngel Pujana, director of the ProCURE Research Programme of the Catalan Institute of Oncology, has identified a novel gene involved in this type of cancer, known as EDC4.

14 Mar 2018

Common genetic variation shown to increase Alzheimer’s risk

A recent study has found that African Americans with a common genetic variation are at an increased risk for developing Alzheimer’s disease.

14 Mar 2018

Medical University of Vienna to partner with bio.logis GIM in pharmacogenetics

Within the framework of U-PGx, an EU project for promoting the use of pharmacogenetic insights in healthcare, the Medical University of Vienna will implement the Genetic Information Management Suite developed by bio.logis Genetic Information Management GmbH.

14 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

ACEA goes live with exhaustive, searchable library of NovoCyte publications

With the 2014 release of its NovoCyte flow cytometer ACEA Biosciences delivered a highly innovative instrument at an extremely competitive price point. In the ensuing three years features such as automated fluidics protocols, a highly flexible and upgradable optical platform, autosampling, direct volumetric cell counting, and the industry leading NovoExpress software have enabled the NovoCyte to quickly gain broad market penetrance.

13 Mar 2018

ACEA launches comprehensive and searchable online library of xCELLigence papers

In 2002 ACEA Biosciences pioneered real-time cellular impedance as a tool for dynamically tracking cell number, cell size, cell-substrate attachment strength, and cell invasion/migration.

13 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

Scientists develop novel assay for studying molecular determinants of bronchoconstriction/dilation

Contraction and relaxation of smooth muscle cells and fibroblasts within the bronchial airways dramatically affects airflow, and being able to modulate these processes is critical for treating asthma and allergic responses.

13 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

ACEA Biosciences enhances NovoCyte Flow Cytometer with multi-option configuration capabilities

The NovoCyte system with its updated software and firmware provides broader versatility and flexibility with its multi-option optical configuration capabilities.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

New imaging technology could significantly improve the accuracy of cancer diagnosis

A new cutting-edge imaging technology can grade cancer tumors, thereby eliminating human subjectivity and variability in the grading of cancer severity.

13 Mar 2018

Study sheds new light on viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine showed how a common virus hijacks a host cell's protein to help assemble new viruses before they are released.

13 Mar 2018

Scientists link 110 genes to increased risk of breast cancer

Scientists have linked 110 genes to an increased risk of breast cancer in the most comprehensive study ever to unpick the genetics of the disease.

13 Mar 2018

Sartorius Stedim Biotech introduces new versions of data analytics software solutions

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry, has introduced a new version of its SIMCA and SIMCA-online data analytical solutions, which are offered by its subsidiary Sartorius Stedim Data Analytics, formerly known as Umetrics.

From Sartorius 13 Mar 2018

Pittcon announces finalists in annual Pittcon Today Excellence Awards

Pittcon, the world’s leading conference and exposition for laboratory science, is pleased to announce the selection of ten finalists in the annual Pittcon Today Excellence Awards conducted by CE Communications, the official publishers of Pittcon Today and the Pittcon Buzz.

From Pittcon 12 Mar 2018

Researchers report genomic sequencing of 250,000 developmental cells

Researchers from the global Human Cell Atlas Consortium report that they have sequenced a quarter of a million separate cells that are of importance for early development of organs such as the liver, skin and kidneys. Sten Linnarsson at Karolinska Institutet is participating in the project.

9 Mar 2018

Aging and lung tissue stiffness contribute to function decline

New research suggests that certain areas of the lungs are more likely than others to show age-related damage that compromises respiratory function. The paper is published ahead of print in the American Journal of Physiology-;Lung Cellular and Molecular Physiology.

9 Mar 2018

Life Science News

Researchers identify novel gene involved in familial breast cancer

Common genetic variation shown to increase Alzheimer’s risk

Medical University of Vienna to partner with bio.logis GIM in pharmacogenetics

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

ACEA goes live with exhaustive, searchable library of NovoCyte publications

ACEA launches comprehensive and searchable online library of xCELLigence papers

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

Scientists develop novel assay for studying molecular determinants of bronchoconstriction/dilation

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

ACEA Biosciences enhances NovoCyte Flow Cytometer with multi-option configuration capabilities

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

New imaging technology could significantly improve the accuracy of cancer diagnosis

Study sheds new light on viral replication

Scientists link 110 genes to increased risk of breast cancer

Sartorius Stedim Biotech introduces new versions of data analytics software solutions

Pittcon announces finalists in annual Pittcon Today Excellence Awards

Researchers report genomic sequencing of 250,000 developmental cells

Aging and lung tissue stiffness contribute to function decline

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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