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Developing software for cell and gene therapy supply chain tracking

The first thing is, to always remember that we're dealing with a living drug, cells, which are very sensitive to environmental conditions, such as temperature and humidity etc. All of those things can impact on the viability of the drug and its effectiveness.

18 Jul 2017

Study provides insights into intergenerational inheritance of epigenetic information

We are more than the sum of our genes. Epigenetic mechanisms modulated by environmental cues such as diet, disease or our lifestyle take a major role in regulating the DNA by switching genes on and off.

18 Jul 2017

Dietary shift from high-fat foods to low-fat diet causes withdrawal-like symptoms in mice

Researchers have found that mice fed a palatable high-fat diet experience stress responses that resemble drug withdrawal when their food is switched to a low-fat diet.

18 Jul 2017

Language development may start in utero, study suggests

A month before they are born, fetuses carried by American mothers-to-be can distinguish between someone speaking to them in English and Japanese.

18 Jul 2017

Scientists find simple way to raise accuracy of diagnostic tests and common assays

Scientists at the University of Washington have discovered a simple way to raise the accuracy of diagnostic tests for medicine and common assays for laboratory research.

18 Jul 2017

New technique physically expands tissues to improve breast cancer diagnosis

A Ludwig Cancer Research study offers pathologists a quick, cheap and reliable tool to diagnose diseases such as early breast cancer with a conventional optical microscope.

18 Jul 2017

Researcher models heart attack in petri dishes to gain insights into cardiac diseases

In petri dishes in her campus laboratory at New Jersey Institute of Technology, Alice Lee is developing colonies of cardiac cells, formed into chambers, that pump and contract like a human heart.

18 Jul 2017

Scientists uncover new genetic markers that predispose individuals to lupus

Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

18 Jul 2017

New analysis compares emerging algorithms that look for cancer mutations

Sanford Burnham Prebys Medical Discovery Institute has undertaken the first-ever comparative analysis of a newly emerging category of algorithms that mine genetic information in cancer databases by focusing on internal gene structure (subgene resolution algorithms), in contrast to classical approaches that focus on genes treated as single units.

17 Jul 2017

New bioanalytical method could pave way for personalized drug therapy

Personalized drug therapy, adjusting the dose, dosage intervals, and the duration of treatment to fit individual patients' needs, are getting more and more important.

17 Jul 2017

NIH researchers show how investigational drug works against rare, fatal genetic disease

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).

17 Jul 2017

Researchers develop simple method for capturing proteins implicated in Alzheimer's, other conditions

A simple methodology for capturing proteins implicated in the development of Alzheimer's disease and other conditions has been developed by researchers at the University of Bradford and University of Dundee.

17 Jul 2017

New optical clearing method helps analyze 3D structure of dangerous blood clots

A new technique that makes blood clots optically clear is allowing researchers to use powerful optical microscopy techniques to study the 3D structure of dangerous clots for the first time.

17 Jul 2017

Study identifies new gene involved in Fanconi anemia

Researchers from the group led by UAB Chair Professor Dr Jordi Surrallés at the Hospital de la Santa Creu i Sant Pau, Barcelona, the Universitat Autònoma de Barcelona and the CIBER of Rare Diseases participated in a study which has led to the identification of a new gene involved in Fanconi anemia, a rare genetic disease.

17 Jul 2017

Scientists develop portable device for detecting circulating tumor cells

Researchers at the URV's Department of Physical and Inorganic Chemistry, led by the ICREA researcher, Ramon Álvarez Puebla, and the professor of Applied Physics, Francesc Díaz, and the Department of Clinical Oncology of the HM Torrelodones University Hospital, have patented a portable device that can detect tumor cells in blood.

17 Jul 2017

Researchers spot two genes that influence person's risk of Alzheimer's disease

A team of researchers led by Cardiff University has identified two genes that influence a person's risk of developing Alzheimer's disease.

17 Jul 2017

Mutations arising after conception may play vital role in autism

A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism.

17 Jul 2017

Black light helps determine disease extent of melasma in pregnant women

Researchers at Boston Medical Center and Boston University School of Medicine have found that using a black light, or Wood's light, helps dermatologists determine disease extent of melasma, a hyperpigmentation condition that causes brown and gray patches to appear on the face.

17 Jul 2017

Subjective well-being can influence physical health

A new review indicates that subjective well-being—factors such as life satisfaction and enjoyment of life—can influence physical health. The review's investigators also examine why this is so and conditions where it is most likely to occur.

17 Jul 2017

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

The placenta, a transient organ that links the developing embryo to its mother, is responsible for nutrient, waste and gas exchange between the fetus and the mother.

17 Jul 2017