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Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

JAX researcher awarded federal grant for genomic studies of healthy aging and Alzheimer's disease

A grant totaling $2,668,127 over five years will fund studies of the complex processes involved in both healthy aging and Alzheimer's disease, in the laboratory of Jackson Laboratory (JAX) Assistant Professor Catherine Kaczorowski, Ph.D.

16 May 2017

New gene variant linked to Lou Gehrig's disease

For the first time, a variant in UBQLN4 gene has been associated with Lou Gehrig's disease or amyotrophic lateral sclerosis (ALS) - a progressive disease resulting in the loss of nerve cells that control muscle movement, which eventually leads to paralysis and death.

15 May 2017

New research explores small fly’s amazing sense of directional hearing

Ormia ochracea's sense of directional hearing is second to none in the animal kingdom. But, according to new University of Toronto Scarborough research, what makes its hearing so incredible may also complicate efforts in using it as a model for new technology, including hearing aids.

15 May 2017

New type of eye drop could potentially revolutionize treatment of AMD

Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionize the treatment of one of the leading causes of blindness in the UK.

15 May 2017

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

A new study shows cells in the initial stage of cancer change their metabolism before getting eliminated by the surrounding normal cells, providing a novel target for developing cancer prevention drugs.

15 May 2017

Research networks focus on investigating spread of antimicrobial resistance in humans, animals

"Antimicrobial-resistant bacteria pose a complex challenge. This is why Germany, with its German Antimicrobial Resistance Strategy DART2020, is making sustained efforts to protect the health of humans and animals", says BfR President Professor Dr. Dr. Andreas Hensel.

12 May 2017

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Analyzing single-cell RNA data in pre-malignant tumors

RNA sequencing is basically the isolation of RNA from cells and the use of reverse transcriptase to turn the RNA into DNA. You can then use your standard DNA sequencing technologies to quantify the cDNA that you obtained from the reverse transcription reaction.

12 May 2017

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That's why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.

12 May 2017

Mayo Clinic research advances understanding of DNA repair mechanisms

We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.

12 May 2017

Study identifies first genetic locus for anorexia nervosa

A landmark study led by UNC School of Medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also be metabolic underpinnings to this potentially deadly illness.

12 May 2017

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

12 May 2017

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Solid Biosciences announced today that new data from two preclinical studies reinforce the potential of its investigational microdystrophin gene therapy, SGT-001, to be an effective treatment approach for Duchenne muscular dystrophy.

11 May 2017

Scientists shed light on evolutionary history of multidrug-resistant enterococci bacteria

Enterococci bacteria are the bane of hospitals, causing thousands of multidrug-resistant infections in patients each year.

11 May 2017

New research sheds light on inner mechanisms underlying learning and memory

New research published online in The FASEB Journal sheds important light on the inner workings of learning and memory.

11 May 2017

New organoid ‘fusion’ technique helps observe complex interactions between diverse brain regions

In 2013 researchers led by IMBA scientist Jürgen Knoblich flabbergasted the scientific community. Starting from human stem cells, researchers in his lab managed to grow living three dimensional models of basic units of human brain in a dish.

11 May 2017

Chemical stimuli by small molecule can improve production of cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage.

11 May 2017

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

11 May 2017

Life Science News

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Study unravels new clues to cause and treatment of spinal muscular atrophy

JAX researcher awarded federal grant for genomic studies of healthy aging and Alzheimer's disease

New gene variant linked to Lou Gehrig's disease

New research explores small fly’s amazing sense of directional hearing

New type of eye drop could potentially revolutionize treatment of AMD

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

Research networks focus on investigating spread of antimicrobial resistance in humans, animals

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Analyzing single-cell RNA data in pre-malignant tumors

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

Mayo Clinic research advances understanding of DNA repair mechanisms

Study identifies first genetic locus for anorexia nervosa

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Scientists shed light on evolutionary history of multidrug-resistant enterococci bacteria

New research sheds light on inner mechanisms underlying learning and memory

New organoid ‘fusion’ technique helps observe complex interactions between diverse brain regions

Chemical stimuli by small molecule can improve production of cartilage cells

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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