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Energy drain from antibiotics spurs bacteria to resist treatment faster

Antibiotics are supposed to wipe out bacteria, yet the drugs can sometimes hand microbes an unexpected advantage.

9 Jun 2025

Shift Bioscience identifies novel single-gene target for safer cellular rejuvenation therapeutics

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the publication of new research identifying a novel, single-gene target for cellular rejuvenation.

9 Jun 2025

New study maps how cells allocate space to organelles during growth

Picture a living cell as if it were a city. If you were the urban planner for this (very little, very alive) city, one of the things you would have to decide is how to allocate space for different functional uses.

6 Jun 2025

Electron microscopy study shows how two enzymes work in tandem to process proteins

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, because they unravel proteins tagged for destruction or recycling.

6 Jun 2025

Mitochondrial DNA variant predicts resistance to melanoma immunotherapy

Results from a new study help resolve the decade-long mystery of why many patients with the deadliest form of skin cancer do not respond to the latest cancer treatments.

6 Jun 2025

Genetic study reveals why some children respond better to myopia lenses

Myopia, or nearsightedness, has reached epidemic levels worldwide, particularly in East and Southeast Asia.

5 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

New anti-aging compounds found hidden beneath the skin

People go to great lengths to maintain youthful-looking skin with masks, creams and serums. Now, researchers have discovered compounds with anti-aging properties hidden beneath our own skin.

5 Jun 2025

Krakencoder reveals neural connections behind brain function

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain's wiring supports the way we think and act.

5 Jun 2025

Loss of Y chromosome in male immune cells linked to poorer cancer outcomes

A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune system function, which may explain why loss of Y is associated with lower cancer survival rates.

5 Jun 2025

Innovative method reveals how titin disruption triggers muscular diseases

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an innovative method, called TEVs-TTN, for studying the specific mechanical functions of proteins through their controlled cleavage, a process that renders the proteins unable to sense and transmit mechanical force.

5 Jun 2025

Unveiling the biological frontier: CRAIC Technologies Circular Dichroism Microspectrometers pioneer molecular insights

CRAIC Technologies is proud to introduce Circular Dichroism Microspectroscopy. The field of biology is witnessing a transformative leap forward with the advent of Circular Dichroism (CD) Microspectroscopy, an innovative analytical technique that bridges micron-scale precision with biological applications.

From CRAIC Technologies, Inc. 5 Jun 2025

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

5 Jun 2025

Understanding how base editing tools work at the molecular level

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

New family of antibiotics derived from the body's own proteins

A team of scientists led by the UAB has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.

4 Jun 2025

Researchers map DNA regions that activate liver regeneration

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection.

4 Jun 2025

LabGenius Therapeutics appoints Dr. Angus Sinclair as Chief Scientific Officer

LabGenius Therapeutics (“LabGenius”) is a drug discovery company combining machine learning (ML) and high-throughput experimentation to optimize complex therapeutic antibodies, including those with multispecific designs.

4 Jun 2025

Early brain wiring holds clues to infant emotional development

In a comprehensive Genomic Press research article, scientists have uncovered remarkable insights into how the earliest brain connections shape infant emotional development, potentially offering new ways to identify children at risk for future behavioral and emotional challenges.

3 Jun 2025

Fruit fly model sheds light on genetic roots of cocaine addiction

In a new JNeurosci paper, Adrian Rothenfluh and colleagues from the University of Utah developed a fruit fly model of cocaine self-administration that can be used to explore the genetic underpinnings of cocaine addiction.

3 Jun 2025