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Change in liver clock could affect synchronization of the circadian cycle

Organisms rely on a biological clock known as the 'circadian' clock to regulate their activity according to the time of day.

17 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Using synthetic peptides for inflammatory disease diagnosis

Scientists have developed a peptide that binds to the protein calprotectin, a marker of major inflammatory disorders, and shown that it is suitable for diagnostic tests.

17 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Owlstone Medical Wins Contract from U.S. Department of Defense to Develop Handheld Breath Biopsy Device for Early Infectious Disease Detection

Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that it had won an award from the U.S. Defense Innovation Unit for ‘Exhaled Breath Diagnostics’.

From Owlstone Medical Ltd 17 May 2023

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Research discusses the activity spectrum of nourseothricin and its components, S-F and S-D, against drug-resistant, gram-negative pathogens. S-F showed promising activity against NDM-1-expressing Klebsiella pneumoniae Nevada strain with minimal toxicity, and it probes the A-decoding site potentially accounting for its miscoding activity.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Machine learning reveals sex-specific Alzheimer's risk genes

Research explores sex-specific gene associations in Alzheimer's disease using a machine-learning approach. It reveals immune response pathways in both sexes and stress-response pathways in males, highlighting potential biomarkers and therapeutic targets for personalized treatments.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

Life Science News

Change in liver clock could affect synchronization of the circadian cycle

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Using synthetic peptides for inflammatory disease diagnosis

Democratizing RNA sequencing: A breakthrough in cost and efficiency

Owlstone Medical Wins Contract from U.S. Department of Defense to Develop Handheld Breath Biopsy Device for Early Infectious Disease Detection

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Study establishes a mechanistic link between obesity and oral cancer immune escape

Glycosylation enzyme plays a crucial role in brain development, study shows

Machine learning reveals sex-specific Alzheimer's risk genes

Molecular mechanism behind a DNA repair pathway revealed

New process for automated and highly accurate reporting of NGS-based clonality testing

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

Researchers discover how the A. baumannii can survive harsh environments

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

Advancing Precision Medicine in Argentina, Brazil and Chile – BGI Update

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

New study reveals a revolutionary approach to studying airborne genetic material

Novel tool paves the way for automated identification and localization of proteins in cells

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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