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Pick's Disease History

Pick’s disease is a complex neurodegenerative disorder characterized by dementia due to damage and shrinkage within the frontal and temporal lobes of the brain. These areas of the brain are responsible for controlling speech and emotion, and as a result, patients with Pick’s disease often have difficulty speaking, understanding vocabulary, and controlling their emotions, especially in social settings.

21 Nov 2009

What is Pick's Disease?

Pick’s disease, also known as Pick disease or PiD, is a rare neurodegenerative disorder involving the progressive destruction of brain cells. It is a type of frontotemporal dementia and is characterized by symptoms of dementia and aphasia.

21 Nov 2009

Motor Neurone Disease Etymology

Motor neurone disease is a rare progressive disorder that affects special nerves in the brain and spinal cord called motorneurons.

21 Nov 2009

Motor Neurone Disease Epidemiology

Motor neurone disease affects about 2 in every 100,000 people each year in the UK and about 5,000 people are living with the disease at any given time.

21 Nov 2009

Motor Neurone Disease Complications

Motor neurone disease is a progressive condition, with symptoms gradually worsening after onset and eventually causing severe disability.

21 Nov 2009

Motor Neurone Disease Prognosis

Motor neurone disease is a progressive neurodegenerative disorder that leads to decreased control of muscle movement and eventually paralysis. Symptoms can be mild at first and a tendency to drop things is often one of the first signs of the condition to develop.

21 Nov 2009

Motor Neurone Disease Treatment

There is currently no known cure for motor neurone disease and treatment is aimed at easing symptoms and helping patients to cope with problems such as difficulty speaking, swallowing or moving about.

21 Nov 2009

Motor Neurone Disease Diagnosis

Motor neurone disease is diagnosed based on a patient’s symptoms, any family history of the disease, a physical examination and a battery of tests to rule out other conditions.

21 Nov 2009

Motor Neurone Disease Symptoms

Motor neurone disease is a progressive neurodegenerative disorder that leads to loss of muscle control and eventually disability and paralysis.

21 Nov 2009

Motor Neurone Disease Pathophysiology

Motor neurone disease is a progressive degenerative disorder affecting specialist nerve cells called motor neurons that control muscle movement.

21 Nov 2009

Motor Neurone Disease Causes

Motor neurone disease is a debilitating condition caused by degeneration of the nerve cells that control muscle movement.

21 Nov 2009

What is Motor Neurone Disease?

Motor neurone disease is a rare condition of the nervous system that leads to loss of muscle control. The disease leads to progressive weakness, muscle wastage and eventually disability.

21 Nov 2009

Huntington's Disease Research Directions

Huntington’s disease is currently the subject of extensive research which is being carried out to understand the mechanism of the huntingtin (Htt) protein and how exactly its mutation causes brain damage.

21 Nov 2009

Huntington's Disease History

Huntington’s disease has been acknowledged as a disorder for hundreds of years but the cause was only established recently. Over the years, Huntington’s disease has been named differently, according to what was understood of the condition. Terms have ranged from “chorea” which refers to the jerky, uncontrolled movements that occur, through to “chronic progressive chorea,” which reflected the observed progressive course of the disease.

21 Nov 2009

Huntington's Disease Society and Culture

Huntington’s disease is an incurable genetic disorder that is inherited in an autosomal dominant manner. A diagnosis of Huntington’s disease can be very distressing for a patient and their family to receive. There is no cure for Huntington’s disease and eventually patients require full-time palliative care.

21 Nov 2009

Huntington's Disease Prognosis

Huntington’s disease is caused by a mutation that occurs in the Huntingtin (HTT) gene, which is located on chromosome 4. The mutation exists as an expansion mutation of the trinucelotide cytosine-adenine-guanine (CAG).

21 Nov 2009

Huntington's Disease Diagnosis

A diagnosis of Huntington’s disease is suspected based on the appearance of specific symptoms. In most cases, these symptoms appear around middle age, when a person is between 35 and 45 years of age.

21 Nov 2009

Huntington's Disease Genetics

All humans possess two alleles for the Huntingtin (HTT) gene. This gene provides instructions for making the protein huntingtin (Htt). Part of the HTT gene contains repeats of the trinucelotide cytosine-adenine-guanine (CAG).

21 Nov 2009

Huntington's Disease Symptoms

Huntington's disease is a genetic condition that affects certain nerve cells in the brain and causes brain damage. This can lead to disorders in movement, cognition and behavior. Although symptoms of the disease can develop at almost any age, they usually begin when a person is aged between 35 and 55 years old.

21 Nov 2009

What is Huntington's Disease?

Huntington’s disease is an incurable neurodegenerative disease that affects muscle coordination and cognitive function. Symptoms of the disease usually start to develop around middle age. Huntington’s disease used to be called Huntington’s chorea because it is the most commonly inherited condition to lead to the involuntary movements referred to as chorea.

21 Nov 2009