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New study provides promising results for metformin in periodontitis

Periodontitis, a prevalent global health concern, results in the gradual destruction of tooth-supporting tissues and is often exacerbated by oxidative stress conditions and bacterial changes. Current treatment methodologies include mechanical debridement, anti-inflammatory drugs, and regenerative surgery.

4 Aug 2023

Racial disparities in mortality rates persist in the United States

An analysis of 19 causes of death in the United States revealed persistent disparities and a familiar pattern across five racial-ethnic groups and 3,110 counties from 2000 to 2019. That's according to the most comprehensive peer-reviewed research published today in The Lancet.

4 Aug 2023

New technique enables high-resolution analysis of DNA

Function and form are deeply intertwined in biology. Knowing how organisms grow, adapt and reproduce requires understanding their physical structures. Hence the transformative power of the microscope across the past four centuries of science.

4 Aug 2023

New study finds more effective way to coach and inspire

What if there was a more effective way to coach and inspire your employees? Athletes? Students? Even your kids?

4 Aug 2023

Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

3 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Researchers discover how aging can lead to chronic metabolic disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

3 Aug 2023

Deep learning improves protein design by 10x

The key to understanding proteins - such as those that govern cancer, COVID-19, and other diseases - is quite simple. Identify their chemical structure and find which other proteins can bind to them. But there's a catch.

3 Aug 2023

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

An accepted manuscript published in the American Journal of Roentgenology (AJR) found that deploying a radiomic-based model with T2-weighted MRI data could increase diagnostic accuracy for pediatric Crohn disease (CD).

3 Aug 2023

Fatal coronary heart disease may rise again unless Americans modify three key risk factors

After decades of decline, fatal coronary heart disease may rise again unless Americans modify three major risk factors: smoking, drinking, and obesity.

3 Aug 2023

Peppermint oil may be new option for pain relief after open heart surgery

The use of essential peppermint oil aromatherapy may ease pain severity after open heart surgery and enhance sleep quality as well, suggest the results of a small comparative clinical trial, published online in the journal BMJ Supportive & Palliative Care.

3 Aug 2023

Independent sector to help cut NHS waiting lists

Thirteen new community diagnostic centres (CDCs) - including eight independently run CDCs - are being launched across the country as part of government plans to use the independent sector to cut NHS waiting lists, Health and Social Care Secretary Steve Barclay will announce today.

3 Aug 2023

Expression of two key genes influences cancer progression

Tissues, blood vessels, cells: tumours develop in a complex ecosystem known as the tumour microenvironment.

3 Aug 2023

Childhood trauma may increase risk of complications during pregnancy

A study led by University of Queensland researchers has found women who have experienced maltreatment, domestic violence or household substance abuse as children have a higher risk of complications during pregnancy.

3 Aug 2023

Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

Study reveals mechanism through which insulin-like growth factors facilitate brain plasticity

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity.

3 Aug 2023

Air pollution linked to increased risk of non-lung cancers in older adults

Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a study led by Harvard T.H. Chan School of Public Health.

3 Aug 2023

Mothers' diet during pregnancy can protect brain health of children and grandchildren

Mothers who eat apples and herbs in early pregnancy could be protecting the brain health of their children and grandchildren, a Monash University study using genetic models has found.

3 Aug 2023

Simple interview technique could help detect early signs of dementia

Research at the Florida State University College of Medicine has identified a potential low-cost method for predicting if a person is at risk of developing dementia.

3 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023