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SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Results from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of patients with rare cancers, are being reported for five cohorts of patients who had rare gynecologic cancers.

18 Apr 2023

Green Mediterranean diet substantially regresses proximal aortic stiffness

The green Mediterranean – high polyphenols diet substantially regresses proximal aortic stiffness (PAS), a marker of vascular aging and increased cardiovascular risk.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit.

18 Apr 2023

Novel score identifies the heart failure patients who benefit most from atrial fibrillation ablation

A score based on four readily available clinical and imaging parameters identifies the heart failure patients who benefit most from atrial fibrillation ablation, according to late-breaking science presented at EHRA 2023, a scientific congress of the European Society of Cardiology.

18 Apr 2023

New software tool set to improve the management of elderly atrial fibrillation patients with comorbidities

A novel software tool set to improve the management of elderly atrial fibrillation patients with multiple conditions is being designed by the EU-funded and ESC-coordinated EHRA-PATHS consortium. The latest updates on this clinical innovation will be presented at EHRA 2023, a scientific congress of the European Society of Cardiology.

18 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Innovative three-step ablation approach holds promise for patients with persistent atrial fibrillation

An innovative three-step ablation approach including ethanol infusion of the vein of Marshall improves freedom from arrhythmias in patients with persistent atrial fibrillation compared to pulmonary vein isolation (PVI) alone, according to late-breaking science presented at EHRA 2023, a scientific congress of the European Society of Cardiology.

18 Apr 2023

Using electric stimulation to make wounds heal three times faster

Chronic wounds are a major health problem for diabetic patients and the elderly – in extreme cases they can even lead to amputation. Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the healing process, making wounds heal three times faster.

18 Apr 2023

Revolutionary new social platform offers a lifeline for Parkinson’s patients

People affected by Parkinson's Disease (PD) are being offered a lifeline in the form of a revolutionary new social platform.

18 Apr 2023

Severe COVID-19 patients 16 times more likely to develop ventricular tachycardia within six months

Patients with severe COVID-19 requiring mechanical ventilation are 16 times more likely to develop ventricular tachycardia within six months compared to their peers without severe infection, according to research presented at EHRA 2023, a scientific congress of the European Society of Cardiology.

18 Apr 2023

Computer-assisted method accurately recognizes the severity of ataxia-related speech disturbances

Researchers at DZNE and the University Hospital Bonn, together with the Berlin-based company PeakProfiling GmbH, have developed a computer-assisted method that recognizes the severity of speech disturbances resulting from ataxia, a brain disease, with great accuracy.

18 Apr 2023

Diagnosing, treating depression can be critical to breast cancer patient’s care and survival

In a recent study, having depression before or after a breast cancer diagnosis was associated with a lower likelihood of survival. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

18 Apr 2023

UVA launches a new center to improve care, health equity

The School of Medicine has launched a new Center for Health Equity and Precision Public Health to improve the health and well-being of rural residents, the economically challenged and minority groups across Virginia and beyond.

18 Apr 2023

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient's cancer-fighting immune cells, thereby allowing tumors to grow freely.

18 Apr 2023

UWaterloo expert helps develop database repository to manage treatment for hemophilia patients

Today is World Hemophilia Day under the theme ‘Access for all: prevention of bleeds as the global standard of care’. Dr. Andrea Edginton, Hallman Director at the University of Waterloo School of Pharmacy, uses her research to help pharmacists, doctors and nurses manage treatment for hemophilia patients that has, in turn, helped these patients lead a better quality of life.

18 Apr 2023

Study shows effectiveness, safety of stereotactic radiosurgery for NF2-related vestibular schwannomas

Vestibular schwannomas related to neurofibromatosis type 2 (NF2) are difficult to manage and are sometimes treated with a noninvasive option, stereotactic radiosurgery.

18 Apr 2023

Newly discovered gene plays crucial role in determining the risk for vascular conditions

University of School of Medicine researchers have identified a gene that plays a crucial role in determining our risk for heart attacks, deadly aneurysms, coronary artery disease and other dangerous vascular conditions.

18 Apr 2023

Fewer resources associated with lower chances of survival after a cardiac arrest

Hospital inpatients have better prospects of surviving a cardiac arrest in large hospitals and well-resourced wards, and daytime cardiac arrests are also associated with better chances of survival, a University of Gothenburg thesis shows.

18 Apr 2023

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a study published in today's issue of Blood.

18 Apr 2023

Medical News

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Green Mediterranean diet substantially regresses proximal aortic stiffness

Researchers discover the molecule responsible for guiding T cells toward tumors

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Novel score identifies the heart failure patients who benefit most from atrial fibrillation ablation

New software tool set to improve the management of elderly atrial fibrillation patients with comorbidities

Precise genome editing approach can correct mutation that causes sickle cell disease

Innovative three-step ablation approach holds promise for patients with persistent atrial fibrillation

Using electric stimulation to make wounds heal three times faster

Revolutionary new social platform offers a lifeline for Parkinson’s patients

Severe COVID-19 patients 16 times more likely to develop ventricular tachycardia within six months

Computer-assisted method accurately recognizes the severity of ataxia-related speech disturbances

Diagnosing, treating depression can be critical to breast cancer patient’s care and survival

UVA launches a new center to improve care, health equity

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

UWaterloo expert helps develop database repository to manage treatment for hemophilia patients

Study shows effectiveness, safety of stereotactic radiosurgery for NF2-related vestibular schwannomas

Newly discovered gene plays crucial role in determining the risk for vascular conditions

Fewer resources associated with lower chances of survival after a cardiac arrest

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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