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Making the nanobody big again for Cryo-EM

Researchers describe the method that allows high-resolution structure determination of small proteins by single-particle cryo-EM using a Legobody.

17 Aug 2021

In UK's 1st wave, 10% of COVID infections were acquired in hospitals

Their study published in The Lancet journal involved assessing the magnitude of hospital-acquired COVID-19 in the case of acute and long-term National Health Service (NHS) hospital facilities in the UK during the first wave of the pandemic.

17 Aug 2021

Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

A study, available on the pre-print server bioRxiv*, evaluated the neutralizing capacity of a fully human polyclonal antibody (SAB-185) against the Delta, Kappa, and Lambda variants using a lentiviral-based pseudovirus assay.

17 Aug 2021

How delta and kappa variants of SARS-CoV-2 evade the immune system

A new study, available on the bioRxiv* preprint server, describes the neutralizing ability of the monoclonal antibodies against the variants and the difference of the ACE2 binding affinity found in the variants.

17 Aug 2021

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Now, a new study posted to the bioRxiv* preprint server focuses on functional immune memory to SARS-CoV-2, up to nine months in a Southeast Asian cohort, in the absence of re-infection.

16 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

The safety, immunogenicity, and efficacy of the vaccines in adolescents are largely unknown. Now, a new study published in the New England Journal of Medicine evaluates the safety and efficacy of the mRNA-1273 vaccine in adolescents (12-17 years of age).

16 Aug 2021

Sighted and blind individuals have similar understanding of color

People born blind have never seen that bananas are yellow but Johns Hopkins University researchers find that like any sighted person, they understand two bananas are likely to be the same color and why.

16 Aug 2021

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

In a recent study, a group of researchers determined the degree to which Pango lineages are distinguishable using spike-only nucleotide sequences.

16 Aug 2021

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

A recent study discusses how New Zealand rapidly employed real-time genomics to contain new COVID-19 cases.

16 Aug 2021

Sphingolipid profile could predict severity of heart disease in African American patients with lupus

A team of researchers at the Medical University of South Carolina report in Frontiers in Immunology that they have identified a type of fat known as a sphingolipid that could predict the severity of heart disease in African American patients with lupus.

16 Aug 2021

Regional policies not sufficient to comprehensively tackle covid-19 infection risk, study suggests

In a new paper published in the The Lancet Regional Health - Europe, Mr Gabriele Guaitoli and Dr Roberto Pancrazi from the Department of Economics at Warwick University investigate whether region-wide non-pharmaceutical interventions introduced in Italy during the second wave of Covid-19 in Fall 2020 have been effective at eliminating local risk factors.

16 Aug 2021

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

It was wartime and food was scarce. Leaders of England's effort to wage war and help the public survive during World War II needed to know: Were the rations in lifeboats adequate for survival at sea? And, among several experiments important for public as well as military heath, how much vitamin C did a person need to avoid the deadly disease scurvy?

16 Aug 2021

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

A form of cell communication called hedgehog signaling is vital for embryonic development in mammals.

16 Aug 2021

Structured daily schedule, passive screen time can promote youth mental health during the pandemic

There are a number of simple, practical steps that families can take - including reducing passive screen time and news consumption, having a structured daily schedule and getting enough sleep - that can promote resilience against mental health problems in youth during the COVID-19 pandemic, according to a new study published this week in the open-access journal PLOS ONE by Maya Rosen of Harvard University, US, and colleagues.

16 Aug 2021

Viral load could not predict transmissibility of SARS-CoV-2, study finds

The transmission of SARS-CoV-2 virus is dependent on many factors. Although some in vitro studies indicate that the amount of virus isolated from infected individuals affects the successful rate of virus transmission, whether the viral load carried at the individual level can determine transmissibility was unknown.

16 Aug 2021

Beneficial and protective effects of SARS-CoV-2 vaccines far outweigh the risk of Bell's palsy

The first large-scale population-based study on the association between the SARS-CoV-2 vaccines and Bell's palsy confirms that the beneficial and protective effects of the vaccines far outweigh the risk of this rare adverse event.

16 Aug 2021

Local perceptions of COVID-19 risk do not correlate with the infection rate, survey finds

Superspreading events have proven to be the primary mode of infection driving the COVID-19 pandemic, which has led to an inaccurate perception of risk.

16 Aug 2021

Treating trauma survivors early may help avoid complicated grief years later

Among individuals who survive a trauma that resulted in the loss of a close friend or loved one, symptoms of post-traumatic stress disorder can predict complicated grief—a sense of persistent sadness and an inability to cope—years after the trauma, according to research published by the American Psychological Association.

16 Aug 2021

Soft, low-cost neuroprosthetic hand offers amputees real-time tactile control

For the more than 5 million people in the world who have undergone an upper-limb amputation, prosthetics have come a long way.

16 Aug 2021

Medical News

Making the nanobody big again for Cryo-EM

In UK's 1st wave, 10% of COVID infections were acquired in hospitals

Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

How delta and kappa variants of SARS-CoV-2 evade the immune system

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

Sighted and blind individuals have similar understanding of color

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

Sphingolipid profile could predict severity of heart disease in African American patients with lupus

Regional policies not sufficient to comprehensively tackle covid-19 infection risk, study suggests

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

Structured daily schedule, passive screen time can promote youth mental health during the pandemic

Viral load could not predict transmissibility of SARS-CoV-2, study finds

Beneficial and protective effects of SARS-CoV-2 vaccines far outweigh the risk of Bell's palsy

Local perceptions of COVID-19 risk do not correlate with the infection rate, survey finds

Treating trauma survivors early may help avoid complicated grief years later

Soft, low-cost neuroprosthetic hand offers amputees real-time tactile control

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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