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NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Newly developed spheroidal structure reproduces the microenvironment of tumors

Every tumor is different, every patient is different. So how do we know which treatment will work best for the patient and eradicate the cancer? In order to offer a personalised treatment that best suits the case being treated, a team of scientists led by the University of Geneva (UNIGE), Switzerland, had already developed a spheroidal reproduction of tumors that integrates the tumor cells, but also their microenvironment.

3 Jun 2021

Single mutation to bat virus spike protein allows cell entry using human ACE2

In a paper recently uploaded to the preprint server bioRxiv by Kirchhoff et al. (May 31st, 2021) it is demonstrated that a single mutation to the RaTG13 spike protein results in significantly greater affinity towards the human receptor, indicating that the presence of a positively charged amino group at this position better facilitates interaction with the human ACE2 receptor, and helping to identify other viruses with zoonotic potential.

3 Jun 2021

European Virtual Institute receives award to explore brain circuits that underlie emotional behavior

A Marie Sklodowska-Curie Innovative Training Network will explore the brain circuits that underlie emotional behavior thanks to funding of 4.5 million euros by the European Research Council.

3 Jun 2021

Experts offer plausible solutions to mitigate zoonotic risk associated with intensive animal agriculture

As early as the Neolithic period (circa 3900 BC), the domestication of animals likely led to the development of diseases including measles and smallpox. Since then, zoonotic disease has led to other major transnational outbreaks including HIV, Ebola, SARS, MERS, and H1N1 swine flu, among others.

3 Jun 2021

Opioid Agonist Therapy can reduce mortality risk in people with opioid dependence

A new global review has found that receiving Opioid Agonist Therapy (OAT) is associated with lower risk of multiple causes of death among people with opioid dependence.

3 Jun 2021

A study of the COVID fatality rates in India during waves 1 and 2

A team of researchers at the Department of Biostatistics, University of Michigan estimated the underreporting factor for infections using publicly available data released by the Indian Council of Medical Research on the reported number of cases and national seroprevalence surveys.

3 Jun 2021

New research sheds light on the origins of synovial sarcoma

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

3 Jun 2021

New study will help design better antibodies for potential treatments

Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright X-ray light to determine how specific types of antibodies can tell the difference between different forms of a cancer-linked molecule.

3 Jun 2021

Tiny implant reverses diabetes in mice without requiring drugs

A team of researchers led by diabetes specialists and biomedical engineers at Washington University School of Medicine in St. Louis and Cornell University has demonstrated that, using a miniscule device, they can implant insulin-secreting cells into diabetic mice.

3 Jun 2021

COVID-19 mortality in Israel and Europe after vaccination

The study, which appeared on the pre-print server, medRxiv*, confirms the potent efficacy of COVID-19 vaccination based on real-life public data in terms of protection against death.

2 Jun 2021

Number of specialty behavioral health establishments have increased but more work needs to be done

The number of specialty behavioral health establishments, their workforce and their wages have increased steadily between 2011 and 2019, according to a new study by Indiana University and University of Michigan researchers.

2 Jun 2021

Ethnic minorities are twice as likely to die after traumatic brain injury

People of color are more than twice as likely to die after a traumatic brain injury as white people, according to a new retrospective review from Oregon Health & Science University.

2 Jun 2021

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

However, a fascinating new study posted to the medRxiv* preprint server suggests that such disappointment may have been both premature and unwarranted, based on a re-analysis of over 250 patients on invasive mechanical ventilation (IMV) during the first two months of the pandemic.

2 Jun 2021

Nanopore sequencing contradicts human genome integration of SARS-CoV-2

Now a new preprint research paper posted to the bioRxiv* server dismisses the possibility, raised by that study, that the virus inserts its genetic material into the host cell’s genome.

2 Jun 2021

Predictors of COVID vaccination uptake in the U.S.

A recent preprint research paper posted to the medRxiv server describes the changing patterns of vaccine uptake in the USA and offers short-term forecasts to help create strategies of vaccine supply as required.

2 Jun 2021

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows.

2 Jun 2021

Long COVID patients at higher risk of small airway disease

The preprint discussed herein describes the effects of SARS-CoV-2 on lung structure and function in patients with long COVID.

2 Jun 2021

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

A new medRxiv* preprint reports the immunomodulatory effect of the E484K mutation newly acquired by the United Kingdom (U.K.) variant.

2 Jun 2021

Partners can directly influence pregnant woman's likelihood of drinking alcohol, study finds

A new study by a team of University of Rochester psychologists and other researchers in the Collaborative Initiative on Fetal Alcohol Spectrum Disorders finds that partners of mothers-to-be can directly influence a pregnant woman's likelihood of drinking alcohol and feeling depressed, which affects their babies' development.

2 Jun 2021

Medical News

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Newly developed spheroidal structure reproduces the microenvironment of tumors

Single mutation to bat virus spike protein allows cell entry using human ACE2

European Virtual Institute receives award to explore brain circuits that underlie emotional behavior

Experts offer plausible solutions to mitigate zoonotic risk associated with intensive animal agriculture

Opioid Agonist Therapy can reduce mortality risk in people with opioid dependence

A study of the COVID fatality rates in India during waves 1 and 2

New research sheds light on the origins of synovial sarcoma

New study will help design better antibodies for potential treatments

Tiny implant reverses diabetes in mice without requiring drugs

COVID-19 mortality in Israel and Europe after vaccination

Number of specialty behavioral health establishments have increased but more work needs to be done

Ethnic minorities are twice as likely to die after traumatic brain injury

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

Nanopore sequencing contradicts human genome integration of SARS-CoV-2

Predictors of COVID vaccination uptake in the U.S.

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

Long COVID patients at higher risk of small airway disease

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

Partners can directly influence pregnant woman's likelihood of drinking alcohol, study finds

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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