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SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Researchers from Switzerland recently investigated humoral and cell-mediated immune responses to mRNA-based vaccines in patients undergoing treatment with CD20-B-cell depleting agents for autoimmune diseases, transplantation, or malignancy.

12 Jul 2021

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

A recent perspective article published in the prestigious journal Science highlights how the use of network-driven strategies for adequately informing rapidly emergent epidemic responses is not only evidence-based but also an equitable way forward for the current coronavirus disease (COVID-19) pandemic and future respiratory pandemics.

12 Jul 2021

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Multivalent protein-based minibinders hold great promise as potential prophylactic and treatment agents, as they can retain their activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern. This was revealed in a recent tour-de-force research study currently available on the bioRxiv* preprint server while the article undergoes the peer review process.

11 Jul 2021

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

The drugmaker Pfizer, one of the companies behind the Pfizer-BioNTech vaccine, or BNT162b2, awaits the green light to develop a COVID-19 booster shot that can protect against emerging variants. Pfizer’s COVID-19 vaccine has been shown to be 95% effective in an ongoing large-scale clinical trial against the original SARS-CoV-2 strain.

11 Jul 2021

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Researchers in Israel have conducted a study showing that the use of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine appears to be safe and effective among patients with cancer.

11 Jul 2021

Novel monoclonal antibody could pave way for future COVID-19 treatments and vaccines

Researchers in the United States have shown that targeting the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral spike protein could achieve broad neutralization of variants of concern.

11 Jul 2021

SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

A new study finds that the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection is low following one episode of the infection.

11 Jul 2021

Antigen testing identifies PCR-positive children with live SARS-CoV-2

A recent study finds that antigen-based testing can reliably identify children who are infectious for SARS-CoV-2.

11 Jul 2021

Initial SARS-CoV-2 vaccination response may predict BNT162b2 booster response, but not AZD1222

A new study finds that the antibody titer values prior to the booster dose of the BNT162b2 vaccine can predict the final antibody response after two doses.

11 Jul 2021

Study examines SARS-CoV-2's inactivation across a range of UVC wavelengths

A recent study published on the preprint server medRxiv* describes the disinfection of SARS-CoV-2 using UVC irradiation at different wavelengths.

11 Jul 2021

New draft guidance addresses FDA’s oversight of foods covered by Systems Recognition Arrangement

In order to fulfill our public health mission and enhance the safety of imported foods in a global world, we must embrace new approaches that take into account the entire supply chain and its complexity.

9 Jul 2021

Mice study identifies pathways that link high-fat diet to atherosclerosis

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments to keep arteries open and flowing.

9 Jul 2021

New project aims to improve early detection of cancer and save lives

The Health Innovation Campus at Lancaster University has brought together a taskforce of experts for a major investigation into the prevalence of cancer in the region, to help improve early detection and save lives.

9 Jul 2021

New stroke rehabilitation pattern based on brain-computer interface and robot technology

Strokes, which occur when the blood supply to part of our brain is interrupted or reduced, are the leading cause of death and disability in the adult population.

9 Jul 2021

MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer

Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by half.

9 Jul 2021

New Brigham–Wyss Diagnostic Accelerator could enable fast creation of diagnostic technologies

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston's Brigham and Women Hospital (Brigham) announce their newly founded Diagnostic Accelerator (Brigham-Wyss DxA).

9 Jul 2021

Three new guidelines released for treatment and management of systemic vasculitis

The American College of Rheumatology, in partnership with the Vasculitis Foundation (VF), released three new guidelines for the treatment and management of systemic vasculitis.

9 Jul 2021

Researchers address ethical decisions related to split liver transplantation

Split liver transplantation (SLT) provides an opportunity to divide a donor liver and offer transplants to two small patients, one or both of whom could be a child. SLT, which is underused in the United States, could be used more widely to decrease the number of deaths of people on transplant waiting lists.

9 Jul 2021

Restructuring SNAP is a straightforward way to eliminate food insecurity in the U.S.

Food insecurity is a major problem in the U.S., and it worsened during the COVID-19 pandemic. The Supplemental Nutrition Assistance Program provides some relief, but millions of Americans still lack adequate access to healthy food. A new study from the University of Illinois proposes a potential solution.

9 Jul 2021

Researchers develop normalized brain growth curve charts for children

In the United States, nearly every pediatric doctor's visit begins with three measurements: weight, height and head circumference. Compared to average growth charts of children across the country, established in the 1970s, a child's numbers can confirm typical development or provide a diagnostic baseline to assess deviations from the curve.

9 Jul 2021

Medical News

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Novel monoclonal antibody could pave way for future COVID-19 treatments and vaccines

SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

Antigen testing identifies PCR-positive children with live SARS-CoV-2

Initial SARS-CoV-2 vaccination response may predict BNT162b2 booster response, but not AZD1222

Study examines SARS-CoV-2's inactivation across a range of UVC wavelengths

New draft guidance addresses FDA’s oversight of foods covered by Systems Recognition Arrangement

Mice study identifies pathways that link high-fat diet to atherosclerosis

New project aims to improve early detection of cancer and save lives

New stroke rehabilitation pattern based on brain-computer interface and robot technology

MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer

New Brigham–Wyss Diagnostic Accelerator could enable fast creation of diagnostic technologies

Three new guidelines released for treatment and management of systemic vasculitis

Researchers address ethical decisions related to split liver transplantation

Restructuring SNAP is a straightforward way to eliminate food insecurity in the U.S.

Researchers develop normalized brain growth curve charts for children

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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