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Researchers uncover differences in itch mechanisms

Chronic skin itching drives more people to the dermatologist than any other condition. In fact, the latest science literature finds that 7% of U.S. adults, and between 10 and 20% of people in developed countries, suffer from dermatitis, a common skin inflammatory condition that causes itching.

21 May 2021

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

21 May 2021

Campylobacter infection can also be spread through sexual contact

Campylobacter infection, one of the most common foodborne illnesses in the Western world, can also be spread through sexual contact, according to a new research discovery by an OU Hudson College of Public Health faculty member, working in conjunction with colleagues in Denmark.

21 May 2021

Trial results show upadacitinib to be the most effective treatment for atopic dermatitis

The findings of a clinical trial by Trinity College Dublin researchers of treatment for atopic dermatitis have been published today in The Lancet journal (Friday, 21st May, 2021).

21 May 2021

Study could lead to new antibiotics to fight bacterial infections

One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows.

21 May 2021

Distribution of lithium in the brain plays key role in depressive disorders

Depressive disorders are among the most frequent illnesses worldwide. The causes are complex and to date only partially understood. The trace element lithium appears to play a role.

21 May 2021

If you are vaccinated, you can dance the night away

Marissa Castrigno was walking through downtown Wilmington, North Carolina, when she spotted the sign in the window of one of her favorite dance clubs.

21 May 2021

Parents and young adults urged to get HPV vaccination back on track

Sanford Burnham Prebys has joined doctors and scientists across America at National Cancer Institute (NCI)-designated cancer centers and other organizations to issue a joint statement urging the nation's physicians, parents and young adults to get the human papillomavirus (HPV) vaccination back on track.

21 May 2021

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Penn University more than doubles the percentage of Black patients in cancer clinical trials

A five-year community outreach and engagement effort by the Abramson Cancer Center at the University of Pennsylvania (ACC) to increase enrollment of Black patients into cancer clinical trials more than doubled the percentage of participants, improving access and treatment for a group with historically low representation in cancer research.

21 May 2021

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

A research team at the University of Alberta, Canada, led by Dr. Daniel Limonta, has described two novel molecules with broad antiviral properties that are effective against a range of virus types, including SARS-CoV-2.

21 May 2021

How do common mutations in SARS-CoV-2’s spike affect its binding affinity with host cell receptors?

Antibodies produced during a previous case of COVID-19 or vaccine-induced immunity are targeted towards S protein, where the neutralizing antibodies attach to the Spike RBD domain. Some of the variants have mutations in their RBD domain, causing resistance to the neutralizing antibodies. However, the effect of these mutations on the affinity and kinetics of the binding of Spike RBD to ACE2 is not clear. A new study has been published on the bioRxiv* preprint server, which deals with the study of affinity and kinetic analysis of the interface between Spike RBD and ACE2 at physiological temperatures.

21 May 2021

Prenatal exposure to air pollution can cause asthma in children

Women who were highly exposed to ultra-fine particles in air pollution during their pregnancy were more likely to have children who developed asthma, according to a study published in the American Journal of Respiratory and Critical Care Medicine in May.

21 May 2021

Pfizer-BioNTech vaccination not associated with platelet activation in new study

Among the devastating complications of severe or critical coronavirus disease 2019 (COVID-19), clot formation ranks high in the adverse impact it creates. An important question is whether SARS-CoV-2-spike-based vaccines also cause such coagulopathies. A new study, released as a preprint on the medRxiv* server, examines this risk for the first time.

21 May 2021

Risk factors for rare COVID-19 complications in children (MIS-C)

While the earlier waves of COVID-19 relatively spared children, some of the affected children have developed a systemic inflammatory condition, with occasionally fatal outcomes. Called multisystem inflammatory syndrome in children (MIS-C), its pathogenesis and risk factors are the subject of a new study on the medRxiv* preprint server.

21 May 2021

Can SARS-CoV-2 trigger amyloidosis?

A new study, released as a preprint on the bioRxiv* server, describes the results of an analysis of the role played by the virus in amyloid formation, with its subsequent effects on the health of various organs and of the whole organism.

21 May 2021

New device detects signs of sudden cardiac death

Scientists of Tomsk Polytechnic University have developed a nanosensor-based hardware and software complex for measurement of cardiac micropotential energies without filtering and averaging-out cardiac cycles in real time.

21 May 2021

Scientists discover novel defensive response to SARS-CoV-2

Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients.

21 May 2021

Electrospun nanofibrous filters capture 99.9 percent of coronavirus aerosols, study finds

Researchers at The George Washington University and the University of California in the U.S. compared the efficacy of surgical and cotton masks, a neck gaiter, and electrospun nanofiber membranes to capture coronavirus aerosols and prevent airborne transmission.

21 May 2021

Should colorectal cancer screening start at age 45?

Colorectal cancer rates among young adults are steadily increasing over the years. The United States Task Force has long recommended that people aged 50 to 75 get screened. Now, the U.S. Preventive Services Task Force updated its 2016 recommendation of colorectal screening for people aged 50, down to 45 years old. The five-year earlier screening can save many lives by allowing earlier diagnosis and treatment of the condition.

21 May 2021