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Pfizer-BioNTech and Sinovac vaccines boost SARS-CoV-2 neutralizing responses

Researchers in the United States and Chile have provided preliminary evidence that individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – mount a robust neutralizing antibody response against the virus that can be significantly boosted by two doses of Sinovac Biotech’s CoronaVac vaccine or one dose of Pfizer-BioNTech’s BNT162b2 vaccine.

21 May 2021

North America has 87% of all unique SARS-CoV-2 S protein variants in the NCBI database among six continents

Recently, a team of researchers from various countries analyzed the unique variants of S proteins across six continents, including Africa, Asia, Oceania, Europe, South America, and North America. They wanted to characterize the unique S protein variants embedded in SARS-CoV-2 genomes infecting millions of people globally.

20 May 2021

Swiss study suggests very low prevalence of long COVID in pediatric population

Researchers from Switzerland recently analyzed long COVID symptoms in children and adolescents with a 6-month follow-up based on their SARS-CoV-2 serology. A longitudinal cohort analysis, the Ciao Corona study investigated SARS-CoV-2 seroprevalence and case clustering among ~2500 children from 55 primary and secondary schools in Zurich, Switzerland.

20 May 2021

Intranasal COVID-19 therapeutic shows promise in preclinical trials

Researchers from the US and Denmark recently described a novel therapeutic option that targets the SARS-CoV-2 ribonucleic acid (RNA) using locked nucleic acid antisense oligonucleotides (LNA ASOs). They identified an LNA ASO that binds to the 5’ leader sequence of SARS-CoV-2 ORF1a/b. This disrupts a highly conserved stem-loop structure with nanomolar efficacy and inhibits viral replication in host cells.

20 May 2021

Plastic chemicals can induce changes in gene that is vital for neurological development

The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden.

20 May 2021

Researchers speculate the low prevalence of COVID-19 in Japan

Protective immune memory--through B cells, which make antibodies, and/or T cells, which in the case of CD8+ T cells can kill virus-infected cells--can be induced by identical but also by related viruses.

20 May 2021

Scientists discover key component to repair the molecular motor of human heart

A team of scientists from Loyola University Chicago's Stritch School of Medicine have discovered a critical component for renewing the heart's molecular motor, which breaks down in heart failure.

20 May 2021

Changes in brain regions can predict the progression of epilepsy, lead to better treatment

Scientists have discovered that the way in which neurons are connected within regions of the brain, can be a better indicator of disease progression and treatment outcomes for people with brain disorders such as epilepsy.

20 May 2021

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease's high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) stem and progenitor cells (HSPC).

20 May 2021

COVID-19 death rate for people with IDD is higher across the U.S.

The COVID-19 death rate for people with intellectual and developmental disabilities (IDD) is higher than the general population in several states across the U.S., according to a new study published in Disability and Health Journal.

20 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Medicare negotiation could save billions of dollars in lower commercial health insurance costs by 2030

As Congress considers legislation to reform prescription drug pricing, a new analysis conducted by the West Health Policy Center and released by its Council for Informed Drug Spending Analysis (CIDSA) estimates that the Elijah E. Cummings Lower Drug Costs Now Act (H.R. 3) could result in hundreds of billions of dollars in lower commercial health insurance costs by 2030.

20 May 2021

Resuming global childhood vaccination campaigns during the COVID-19 pandemic

New research published on the medRxiv* preprint server suggests childhood vaccination to prevent other infectious diseases has plummeted during the pandemic. The decrease appears to stem from the suspension of health campaigns promoting immunization and the risk of catching the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

20 May 2021

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

In spite of decades of research, cancer remains an enigma. Conventional wisdom holds that cancer is driven by random mutations that create aberrant cells that run amok in the body.

20 May 2021

COVID-19 cases in summer 2020 was not as low as previously thought, new genome-based model suggests

Many have attributed the low number of coronavirus disease 2019 (COVID-19) cases in the summer of 2020 to hot weather or increased outdoor activities. But a new study from researchers in Germany suggests this might not have been the case.

20 May 2021

WHO’s new guidance sets essential standards to fight malaria, other vector-borne diseases

New guidance from the World Health Organization (WHO) sets essential standards to inform future research and development on genetically modified mosquitoes, particularly in addressing issues relating to ethics, safety, affordability and effectiveness.

20 May 2021

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference.

20 May 2021

World Health Assembly highlights the urgency to end COVID-19 pandemic and prevent the next one

In a year when COVID-19 threatens the health and well-being of everyone on the planet, the seventy-fourth session of the World Health Assembly (WHA) will stress the urgency of ending the current pandemic and preventing the next one by building a healthier, safer and fairer world.

20 May 2021

Seniors enrolled in both Medicare and Medicaid can experience worse outcomes after ICU hospitalization

Seniors who are enrolled in both Medicare and Medicaid are at risk for experiencing greater worsening of functional status following ICU hospitalization, according to research presented at the ATS 2021 International Conference.

20 May 2021

Medical News

Pfizer-BioNTech and Sinovac vaccines boost SARS-CoV-2 neutralizing responses

North America has 87% of all unique SARS-CoV-2 S protein variants in the NCBI database among six continents

Swiss study suggests very low prevalence of long COVID in pediatric population

Intranasal COVID-19 therapeutic shows promise in preclinical trials

Plastic chemicals can induce changes in gene that is vital for neurological development

Researchers speculate the low prevalence of COVID-19 in Japan

Scientists discover key component to repair the molecular motor of human heart

Changes in brain regions can predict the progression of epilepsy, lead to better treatment

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

COVID-19 death rate for people with IDD is higher across the U.S.

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Medicare negotiation could save billions of dollars in lower commercial health insurance costs by 2030

Resuming global childhood vaccination campaigns during the COVID-19 pandemic

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

COVID-19 cases in summer 2020 was not as low as previously thought, new genome-based model suggests

WHO’s new guidance sets essential standards to fight malaria, other vector-borne diseases

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

World Health Assembly highlights the urgency to end COVID-19 pandemic and prevent the next one

Seniors enrolled in both Medicare and Medicaid can experience worse outcomes after ICU hospitalization

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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